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August 14th, 2014

New Research Group "Epigenetic Regulation of Mammalian Ageing" at the MPI for Biology of Ageing


On August 1st Dr. Xiangru Xu officially started his lab at the Max Planck Institute for Biology of Ageing as a Research Group Leader in "Epigenetic Regulation of Mammalian Ageing". Recent studies indicate that epigenetics play a fundamental role both in the normal ageing process and in the pathogenesis of a number of age-related disorders. In epigenetics, scientists study heritable changes in the chromosomes that are not caused by changes in the DNA sequence: changes that occur in an individual's life time, caused by environmental factors.

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August 07th, 2014

Publication in Science: toxic proteins cause neurodegeneration in motor neuron disease and dementia


Recent findings in basic biomedical research might pave the way towards novel therapies: Scientists at the Max Planck Institute for Biology of Ageing in Cologne and University College London have now unearthed the way in which a specific genetic mutation leads to neuronal damage in two serious afflictions, that might even occur at once in a single person: Hitherto, it has been unknown what causes amyotrophic lateral sclerosis and frontotemporal dementia. Now, the scientists have uncovered that a specific genetic mutation entails the production of arginine-containing proteins that are highly neuro toxic.

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July 31st, 2014

Highly competitive EMBO Long-Term Fellowship won by postdoctoral researcher Yu-Xuan Lu of the MPI for Biology of Ageing


International exchange is a key feature in an EMBO Long-Term Fellowship. It supports postdoctoral researcher visits to laboratories throughout Europe and the world for up to two years. "Quite a lot of young scientists apply for this. That Yu-Xuan has won an EMBO fellowship for a full two years is an enormous success", says Linda Partridge, Director at at the MPI for Biology of Ageing and heading the Department "Biological Mechanisms of Ageing", where Yu-Xuan Lu persues his research. The EMBO fellowship is meant to support his project on the relationship between histone methylation and insulin pathway in ageing.

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