Core Facilities

Bioinformatics Core Facility: high-quality user support in bioinformatics analysis

Bioinformatics

The Bioinformatics Core Facility at the MPI for Biology of Ageing actively participates and supports the research staff in all areas of bioinformatics analysis. We are furthermore integrated in the Habermann lab and are thereby able to offer development of custom-based bioinformatics tools and in-depth analysis of datasets. [more...]

Selected publications

Cámara Y, Asin-Cayuela J, Park CB, Metodiev MD, Shi Y, Ruzzenente B, Kukat C, Habermann B, Wibom R, Hultenby K, Franz T, Erdjument-Bromage H, Tempst P, Hallberg BM, Gustafsson CM, Larsson NG. (2011). MTERF4 regulates translation by targeting the methyltransferase NSUN4 to the mammalian mitochondrial ribosome. Cell Metab 13, 527-539.

O'Donnell L, Panier S, Wildenhain J, Tkach JM, Al-Hakim A, Landry MC, Escribano-Diaz C, Szilard RK, Young JT, Munro M, Canny MD, Kolas NK, Zhang W, Harding SM, Ylanko J, Mendez M, Mullin M, Sun T, Habermann B, Datti A, Bristow RG, Gingras AC, Tyers MD, Brown GW, Durocher D. (2010). The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombination. Mol Cell 40, 619-631.

Collinet C, Stöter M, Bradshaw CR, Samusik N, Rink JC, Kenski D, Habermann B, Buchholz F, Henschel R, Mueller MS, Nagel WE, Fava E, Kalaidzidis Y, Zerial M.  (2010). Systems survey of endocytosis by multiparametric image analysis. Nature 464, 243-249.

Shevchenko, A., Roguev, A., Schaft, D., Buchanan, L., Habermann, B., Sakalar, C., Thomas, H., Krogan, N.J., and Stewart, A.F. (2008). Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment. Genome Biol 9, R167.

Schenck, A., Goto-Silva, L., Collinet, C., Rhinn, M., Giner, A., Habermann, B., Brand, M., and Zerial, M. (2008). The endosomal protein Appl1 mediates Akt substrate specificity and cell survival in vertebrate development. Cell 133, 486-497.

Our online tools and resources

DEQOR

RiDDLE

SeLOX

ProFAT (currently unavailable)

HMMerThread database

EST-databases (Axolotl, Worm, Dog)

The Bioinformatics service group of Bianca Habermann relocated to the MPI of Biochemistry in Martinsried from the 1st July 2013.