Research Group Habermann
- Bioinformatics @ MPI-AGE: understanding biology from single molecules to networks.
Bioinformatics
As Bioinformaticians, our mission is to make sense of biological data. We are active in several research areas of Bioinformatics. These include detection of remote sequence similarity, the interpretation of next-generation sequencing data, as well as interpreting large datasets using methods from network analysis. [more...]
Selected publications
Bradshaw, C.R., Surendranath, V., Henschel, R., Mueller, M.S., and Habermann, B.H. (2011). HMMerThread: detecting remote, functional conserved domains in entire genomes by combining relaxed sequence-database searches with fold recognition. PLoS One 6, e17568.
Surendranath, V., Chusainow, J., Hauber, J., Buchholz, F., and Habermann, B.H. (2010). SeLOX--a locus of recombination site search tool for the detection and directed evolution of site-specific recombination systems. Nucleic Acids Res 38, W293-298.
Collinet C, Stöter M, Bradshaw CR, Samusik N, Rink JC, Kenski D, Habermann B, Buchholz F, Henschel R, Mueller MS, Nagel WE, Fava E, Kalaidzidis Y, Zerial M. (2010). Systems survey of endocytosis by multiparametric image analysis. Nature 464, 243-249.
Kittler R*, Surendranath V*, Heninger AK, Slabicki M, Theis M, Putz G, Franke K, Caldarelli A, Grabner H, Kozak K, Wagner J, Rees E, Korn B, Frenzel C, Sachse C, Sönnichsen B, Guo J, Schelter J, Burchard J, Linsley PS, Jackson AL, Habermann B#, Buchholz F#. (2007). Genome-wide resources of endoribonuclease-prepared short interfering RNAs for specific loss-of-function studies. Nat Methods 4, 337-344. * - equal contribution; # - co-corresponding authors
Henschel, A., Buchholz, F., and Habermann, B. (2004). DEQOR: a web-based tool for the design and quality control of siRNAs. Nucleic Acids Res 32, W113-120.
Third-party funding
- 2010-2015 | BMBF
Virtual Liver Newtwork
- BMBF
SyBACol
- BMBF
NGS goes HPC
Our online tools and resources
ProFAT (currently unavailable)
EST-databases (Axolotl, Worm, Dog)
