Publikationen Abteilung Antebi

Nucleolar fibrillarin is an evolutionarily conserved regulator of bacterial pathogen resistance

  • Tiku, V.
  • Kew, C.
  • Mehrotra, P.
  • Ganesan, R.
  • Robinson, N.
  • Antebi, A.
(2018) Nat Commun, 9, 1, 3607

Nucleolar Function in Lifespan Regulation

  • Tiku, V.
  • Antebi, A.
(2018) Trends Cell Biol

A novel EI-GC/MS method for the accurate quantification of anti-aging compound oleoylethanolamine in C. elegans

  • Annibal, A.
  • Karalay, o.
  • Latza, C.
  • Antebi, A.**
(2018) Analytical Methods, 22

LIN-28 balances longevity and germline stem cell number in Caenorhabditis elegans through let-7/AKT/DAF-16 axis

  • Wang, D.
  • Hou, L.
  • Nakamura, S.
  • Su, M.
  • Li, F.
  • Chen, W.
  • Yan, Y.
  • Green, C. D.
  • Chen, D.
  • Zhang, H.
  • Antebi, A.
  • Han, J. J.
(2017) Aging Cell, 2017 Feb, 16(1), 113-124

Role of the Max Planck Institute in Ageing Research in Germany

  • Valenzano, D. R.
  • Antebi, A.
(2017) Experimental Medicine (Japan), 35: 76-83

Small nucleoli are a cellular hallmark of longevity

  • Tiku, V.
  • Jain, C.
  • Raz, Y.
  • Nakamura, S.
  • Heestand, B.
  • Liu, W.
  • Spath, M.
  • Suchiman, H. E. D.
  • Muller, R. U.
  • Slagboom, P. E.
  • Partridge, L.
  • Antebi, A.
(2017) Nat Commun, 8, 16083

Larval crowding accelerates C. elegans development and reduces lifespan

  • Ludewig, A. H.
  • Gimond, C.
  • Judkins, J. C.
  • Thornton, S.
  • Pulido, D. C.
  • Micikas, R. J.
  • Doring, F.
  • Antebi, A.
  • Braendle, C.
  • Schroeder, F. C.
(2017) PLoS Genet, 13, 4, e1006717

Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an alpha-glucosidase inhibitor or a Nrf2-inducer

  • Strong, R.
  • Miller, R. A.
  • Antebi, A.
  • Astle, C. M.
  • Bogue, M.
  • Denzel, M. S.
  • Fernandez, E.
  • Flurkey, K.
  • Hamilton, K. L.
  • Lamming, D. W.
  • Javors, M. A.
  • de Magalhaes, J. P.
  • Martinez, P. A.
  • McCord, J. M.
  • Miller, B. F.
  • Muller, M.
  • Nelson, J. F.
  • Ndukum, J.
  • Rainger, G. E.
  • Richardson, A.
  • Sabatini, D. M.
  • Salmon, A. B.
  • Simpkins, J. W.
  • Steegenga, W. T.
  • Nadon, N. L.
  • Harrison, D. E.
(2016) Aging Cell, 15, 5, 872-84

Mondo complexes regulate TFEB via TOR inhibition to promote longevity in response to gonadal signals

  • Nakamura, S.
  • Karalay, O.
  • Jager, P. S.
  • Horikawa, M.
  • Klein, C.
  • Nakamura, K.
  • Latza, C.
  • Templer, S. E.
  • Dieterich, C.
  • Antebi, A.
(2016) Nat Commun, 7, 10944

Oral Supplementation of Glucosamine Fails to Alleviate Acute Kidney Injury in Renal Ischemia-Reperfusion Damage

  • Johnsen, M.
  • Spath, M. R.
  • Denzel, M. S.
  • Gobel, H.
  • Kubacki, T.
  • Hoyer, K. J.
  • Hinze, Y.
  • Benzing, T.
  • Schermer, B.
  • Antebi, A.
  • Burst, V.
  • Muller, R. U.
(2016) PLoS One, 11, 8, e0161315

Mutation of C. elegans demethylase spr-5 extends transgenerational longevity

  • Greer, E. L.
  • Becker, B.
  • Latza, C.
  • Antebi, A.
  • Shi, Y.
(2016) Cell Res, 26, 2, 229-38

Interventions to Slow Aging in Humans: Are We Ready?

  • Longo, V. D.
  • Antebi, A.
  • Bartke, A.
  • Barzilai, N.
  • Brown-Borg, H. M.
  • Caruso, C.
  • Curiel, T. J.
  • de Cabo, R.
  • Franceschi, C.
  • Gems, D.
  • Ingram, D. K.
  • Johnson, T. E.
  • Kennedy, B. K.
  • Kenyon, C.
  • Klein, S.
  • Kopchick, J. J.
  • Lepperdinger, G.
  • Madeo, F.
  • Mirisola, M. G.
  • Mitchell, J. R.
  • Passarino, G.
  • Rudolph, K. L.
  • Sedivy, J. M.
  • Shadel, G. S.
  • Sinclair, D. A.
  • Spindler, S. R.
  • Suh, Y.
  • Vijg, J.
  • Vinciguerra, M.
  • Fontana, L.
(2015) Aging Cell, 14, 4, 497-510

Co-chaperone p23 regulates C. elegans Lifespan in Response to Temperature

  • Horikawa, M.
  • Sural, S.
  • Hsu, A. L.
  • Antebi, A.
(2015) PLoS Genet, 11, 4, e1005023

Hexosamine pathway and (ER) protein quality control

  • Denzel, M. S.
  • Antebi, A.
(2015) Curr Opin Cell Biol, 33, 14-8

Nuclear receptor signal transduction in C. elegans

  • Antebi, A.
(2015) WormBook, 1-49

Comparative metabolomics reveals endogenous ligands of DAF-12, a nuclear hormone receptor, regulating C. elegans development and lifespan

  • Mahanti, P.
  • Bose, N.
  • Bethke, A.
  • Judkins, J. C.
  • Wollam, J.
  • Dumas, K. J.
  • Zimmerman, A. M.
  • Campbell, S. L.
  • Hu, P. J.
  • Antebi, A.
  • Schroeder, F. C.
(2014) Cell Metab, 19, 1, 73-83

A photocleavable masked nuclear-receptor ligand enables temporal control of C. elegans development

  • Judkins, J. C.
  • Mahanti, P.
  • Hoffman, J. B.
  • Yim, I.
  • Antebi, A.
  • Schroeder, F. C.
(2014) Angew Chem Int Ed Engl, 53, 8, 2110-3

DRE-1/FBXO11-dependent degradation of BLMP-1/BLIMP-1 governs C. elegans developmental timing and maturation

  • Horn, M.
  • Geisen, C.
  • Cermak, L.
  • Becker, B.
  • Nakamura, S.
  • Klein, C.
  • Pagano, M.
  • Antebi, A.
(2014) Dev Cell, 28, 6, 697-710

An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology

  • Fernandes de Abreu, D. A.
  • Caballero, A.
  • Fardel, P.
  • Stroustrup, N.
  • Chen, Z.
  • Lee, K.
  • Keyes, W. D.
  • Nash, Z. M.
  • Lopez-Moyado, I. F.
  • Vaggi, F.
  • Cornils, A.
  • Regenass, M.
  • Neagu, A.
  • Ostojic, I.
  • Liu, C.
  • Cho, Y.
  • Sifoglu, D.
  • Shen, Y.
  • Fontana, W.
  • Lu, H.
  • Csikasz-Nagy, A.
  • Murphy, C. T.
  • Antebi, A.
  • Blanc, E.
  • Apfeld, J.
  • Zhang, Y.
  • Alcedo, J.
  • Ch'ng, Q.
(2014) PLoS Genet, 10, 3, e1004225

Hexosamine pathway metabolites enhance protein quality control and prolong life

  • Denzel, M. S.
  • Storm, N. J.
  • Gutschmidt, A.
  • Baddi, R.
  • Hinze, Y.
  • Jarosch, E.
  • Sommer, T.
  • Hoppe, T.
  • Antebi, A.
(2014) Cell, 156, 6, 1167-78

Aging Cell: open access to all

  • Adams, P.
  • Antebi, A.
  • Cuervo, A. M.
  • Kennedy, B.
  • Sedivy, J.
(2014) Aging Cell, 13, 1, 1

Regulation of the CRL4(Cdt2) ubiquitin ligase and cell-cycle exit by the SCF(Fbxo11) ubiquitin ligase

  • Rossi, M.
  • Duan, S.
  • Jeong, Y. T.
  • Horn, M.
  • Saraf, A.
  • Florens, L.
  • Washburn, M. P.
  • Antebi, A.
  • Pagano, M.
(2013) Mol Cell, 49, 6, 1159-66

The NHR-8 nuclear receptor regulates cholesterol and bile acid homeostasis in C. elegans

  • Magner, D. B.
  • Wollam, J.
  • Shen, Y.
  • Hoppe, C.
  • Li, D.
  • Latza, C.
  • Rottiers, V.
  • Hutter, H.
  • Antebi, A.
(2013) Cell Metab, 18, 2, 212-24

Dietary restriction induced longevity is mediated by nuclear receptor NHR-62 in Caenorhabditis elegans

  • Heestand, B. N.
  • Shen, Y.
  • Liu, W.
  • Magner, D. B.
  • Storm, N.
  • Meharg, C.
  • Habermann, B.
  • Antebi, A.
(2013) PLoS Genet, 9, 7, e1003651

Regulation of longevity by the reproductive system

  • Antebi, A.
(2013) Exp Gerontol, 48, 7, 596-602

Steroid regulation of C. elegans diapause, developmental timing, and longevity

  • Antebi, A.
(2013) Curr Top Dev Biol, 105, 181-212

Aging Cell in 2012. Editorial

  • Adams, P.
  • Antebi, A.
  • Cuervo, A. M.
  • Kennedy, B.
  • Sedivy, J.
(2013) Aging Cell, 12, 1, 1

A novel 3-hydroxysteroid dehydrogenase that regulates reproductive development and longevity

  • Wollam, J.
  • Magner, D. B.
  • Magomedova, L.
  • Rass, E.
  • Shen, Y.
  • Rottiers, V.
  • Habermann, B.
  • Cummins, C. L.
  • Antebi, A.
(2012) PLoS Biol, 10, 4, e1001305

Regulation of neuronal APL-1 expression by cholesterol starvation

  • Wiese, M.
  • Antebi, A.
  • Zheng, H.
(2012) PLoS One, 7, 2, e32038

A steroid receptor-microRNA switch regulates life span in response to signals from the gonad

  • Shen, Y.
  • Wollam, J.
  • Magner, D.
  • Karalay, O.
  • Antebi, A.
(2012) Science, 338, 6113, 1472-6

Hormonal signal amplification mediates environmental conditions during development and controls an irreversible commitment to adulthood

  • Schaedel, O. N.
  • Gerisch, B.
  • Antebi, A.
  • Sternberg, P. W.
(2012) PLoS Biol, 10, 4, e1001306

The Rieske oxygenase DAF-36 functions as a cholesterol 7-desaturase in steroidogenic pathways governing longevity

  • Wollam, J.
  • Magomedova, L.
  • Magner, D. B.
  • Shen, Y.
  • Rottiers, V.
  • Motola, D. L.
  • Mangelsdorf, D. J.
  • Cummins, C. L.
  • Antebi, A.
(2011) Aging Cell, 10, 5, 879-84

Sterol regulation of metabolism, homeostasis, and development

  • Wollam, J.
  • Antebi, A.
(2011) Annu Rev Biochem, 80, 885-916

Molecular basis of life history regulation in C. Elegans and other organisms

  • Gerisch, B.
  • Antebi, A.
(2011) Mechanisms of Life History Evolution

Intracellular trafficking and synaptic function of APL-1 in Caenorhabditis elegans

  • Wiese, M.
  • Antebi, A.
  • Zheng, H.
(2010) PLoS One, 5, 9

A conserved endocrine mechanism controls the formation of dauer and infective larvae in nematodes

  • Ogawa, A.
  • Streit, A.
  • Antebi, A.
  • Sommer, R. J.
(2009) Curr Biol, 19, 1, 67-71

Mitochondrial DNA level, but not active replicase, is essential for Caenorhabditis elegans development

  • Bratic, I.
  • Hench, J.
  • Henriksson, J.
  • Antebi, A.
  • Burglin, T. R.
  • Trifunovic, A.
(2009) Nucleic Acids Res, 37, 6, 1817-28

Nuclear hormone receptor regulation of microRNAs controls developmental progression

  • Bethke, A.
  • Fielenbach, N.
  • Wang, Z.
  • Mangelsdorf, D. J.
  • Antebi, A.
(2009) Science, 324, 5923, 95-8

Announcements from your Editorial Team

  • Antebi, A.
  • Cuervo, A. M.
  • Miller, R.
  • Sedivy, J.
(2009) Aging Cell, 8, 1, 1-1

Caenorhabditis elegans nuclear receptors: insights into life traits

  • Magner, D. B.
  • Antebi, A.
(2008) Trends Endocrinol Metab, 19, 5, 153-60

Syntheses and biological evaluation of B-ring-modified analogues of dafachronic acid A

  • Giroux, S.
  • Bethke, A.
  • Fielenbach, N.
  • Antebi, A.
  • Corey, E. J.
(2008) Org Lett, 10, 16, 3643-5

C. elegans dauer formation and the molecular basis of plasticity

  • Fielenbach, N.
  • Antebi, A.
(2008) Genes Dev, 22, 16, 2149-65

A bile acid-like steroid modulates Caenorhabditis elegans lifespan through nuclear receptor signaling

  • Gerisch, B.
  • Rottiers, V.
  • Li, D.
  • Motola, D. L.
  • Cummins, C. L.
  • Lehrach, H.
  • Mangelsdorf, D. J.
  • Antebi, A.
(2007) Proc Natl Acad Sci U S A, 104, 12, 5014-9

DRE-1: an evolutionarily conserved F box protein that regulates C. elegans developmental age

  • Fielenbach, N.
  • Guardavaccaro, D.
  • Neubert, K.
  • Chan, T.
  • Li, D.
  • Feng, Q.
  • Hutter, H.
  • Pagano, M.
  • Antebi, A.
(2007) Dev Cell, 12, 3, 443-55

Model Organismen des Alterns

  • Antebi, A.
(2007) Die Zukunft des Alterns

Ageing: when less is more

  • Antebi, A.
(2007) Nature, 447, 7144, 536-7

Genetics of aging in Caenorhabditis elegans

  • Antebi, A.
(2007) PLoS Genet, 3, 9, 1565-71

Hormonal control of C. elegans dauer formation and life span by a Rieske-like oxygenase

  • Rottiers, V.
  • Motola, D. L.
  • Gerisch, B.
  • Cummins, C. L.
  • Nishiwaki, K.
  • Mangelsdorf, D. J.
  • Antebi, A.
(2006) Dev Cell, 10, 4, 473-82

Control of Caenorhabditis elegans life history by nuclear receptor signal transduction

  • Rottiers, V.
  • Antebi, A.
(2006) Exp Gerontol, 41, 10, 904-9

Identification of ligands for DAF-12 that govern dauer formation and reproduction in C. elegans

  • Motola, D. L.
  • Cummins, C. L.
  • Rottiers, V.
  • Sharma, K. K.
  • Li, T.
  • Li, Y.
  • Suino-Powell, K.
  • Xu, H. E.
  • Auchus, R. J.
  • Antebi, A.
  • Mangelsdorf, D. J.
(2006) Cell, 124, 6, 1209-23

Nuclear hormone receptors in C. elegans

  • Antebi, A.
(2006) WormBook, 1-13

mab-2 encodes RNT-1, a C. elegans Runx homologue essential for controlling cell proliferation in a stem cell-like developmental lineage

  • Nimmo, R.
  • Antebi, A.
  • Woollard, A.
(2005) Development, 132, 22, 5043-54

Caenorhabditis elegans as a Model Organism for Functional Genomics

  • Antebi, A.
(2005) Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine, pp.189-193

Physiology. The tick-tock of aging?

  • Antebi, A.
(2005) Science, 310, 5756, 1911-3

The prepared mind of the worm

  • Antebi, A.
(2005) Cell Metab, 1, 3, 157-8

Identification of C. elegans DAF-12-binding sites, response elements, and target genes

  • Shostak, Y.
  • Van Gilst, M. R.
  • Antebi, A.
  • Yamamoto, K. R.
(2004) Genes Dev, 18, 20, 2529-44

A novel nuclear receptor/coregulator complex controls C. elegans lipid metabolism, larval development, and aging

  • Ludewig, A. H.
  • Kober-Eisermann, C.
  • Weitzel, C.
  • Bethke, A.
  • Neubert, K.
  • Gerisch, B.
  • Hutter, H.
  • Antebi, A.
(2004) Genes Dev, 18, 17, 2120-33

Hormonal signals produced by DAF-9/cytochrome P450 regulate C. elegans dauer diapause in response to environmental cues

  • Gerisch, B.
  • Antebi, A.
(2004) Development, 131, 8, 1765-76

Tipping the balance toward longevity

  • Antebi, A.
(2004) Dev Cell, 6, 3, 315-6

Inside insulin signaling, communication is key to long life

  • Antebi, A.
(2004) Sci Aging Knowledge Environ, 2004, 23, pe25

Long life: a matter of taste (and smell)

  • Antebi, A.
(2004) Neuron, 41, 1, 1-3

The endocrine regulation of aging by insulin-like signals

  • Tatar, M.
  • Bartke, A.
  • Antebi, A.
(2003) Science, 299, 5611, 1346-51

A hormonal signaling pathway influencing C. elegans metabolism, reproductive development, and life span

  • Gerisch, B.
  • Weitzel, C.
  • Kober-Eisermann, C.
  • Rottiers, V.
  • Antebi, A.
(2001) Dev Cell, 1, 6, 841-51

daf-12 encodes a nuclear receptor that regulates the dauer diapause and developmental age in C. elegans

  • Antebi, A.
  • Yeh, W. H.
  • Tait, D.
  • Hedgecock, E. M.
  • Riddle, D. L.
(2000) Genes Dev, 14, 12, 1512-27

daf-12 regulates developmental age and the dauer alternative in Caenorhabditis elegans

  • Antebi, A.
  • Culotti, J. G.
  • Hedgecock, E. M.
(1998) Development, 125, 7, 1191-205

Cell and Growth Cone Migrations

  • Antebi, A.
  • Norris, C. R.
  • Hedgecock, E. M.
  • Garriga, G.
(1997) C. elegans II

PMR1

  • Antebi, A.
  • Fink, G.R.
(1994) Guidebook to the Secretory Pathway

The yeast Ca(2+)-ATPase homologue, PMR1, is required for normal Golgi function and localizes in a novel Golgi-like distribution

  • Antebi, A.
  • Fink, G. R.
(1992) Mol Biol Cell, 3, 6, 633-54

The yeast secretory pathway is perturbed by mutations in PMR1, a member of a Ca2+ ATPase family

  • Rudolph, H. K.
  • Antebi, A.
  • Fink, G. R.
  • Buckley, C. M.
  • Dorman, T. E.
  • LeVitre, J.
  • Davidow, L. S.
  • Mao, J. I.
  • Moir, D. T.
(1989) Cell, 58, 1, 133-45

Molecular complexes of nucleosides and nucleotides with a monomeric cationic porphyrin and some of its metal derivatives

  • Pasternack, R. F.
  • Gibbs, E. J.
  • Gaudemer, A.
  • Antebi, A.
  • Bassner, S.
  • De Poy, L.
  • Turner, D. H.
  • Williams, A.
  • Laplace, F.
  • Lansard, M. H.
  • Merienne, C.
  • Perree-Fauvet, M.
(1985) J Am Chem Soc, 107, 26, 8179-8186

*gleichwertiger Beitrag; **Korrespondenzautor