SERVICEEINHEIT PHÄNOTYPISIERUNG

Publikationen

Reduced insulin signaling in neurons induces sex-specific health benefits

  • Baghdadi, M.
  • Nespital, T.
  • Mesaros, A.
  • Buschbaum, S.
  • Withers, D. J.
  • Gronke, S.
  • Partridge, L.
(2023) Sci Adv, 9, 8, eade8137

Heterogeneous effects of individual high-fat diet compositions on phenotype, metabolic outcome, and hepatic proteome signature in BL/6 male mice

  • Janoschek, R.
  • Handwerk, M.
  • Hucklenbruch-Rother, E.
  • Schmitz, L.
  • Bae-Gartz, I.
  • Kasper, P.
  • Lackmann, J. W.
  • Kretschmer, T.
  • Vohlen, C.
  • Mesaros, A.
  • Purrio, M.
  • Quaas, A.
  • Dotsch, J.
  • Appel, S.
(2023) Nutr Metab (Lond), 20, 1, 8

Cannabinoid CB1 Receptor Deletion from Catecholaminergic Neurons Protects from Diet-Induced Obesity

  • Srivastava, R. K.
  • Ruiz de Azua, I.
  • Conrad, A.
  • Purrio, M.
  • Lutz, B.
(2022) Int J Mol Sci, 23, 20

Hexosamine pathway activation improves memory but does not extend lifespan in mice

  • Allmeroth, K.
  • Hartman, M. D.
  • Purrio, M.
  • Mesaros, A.
  • Denzel, M. S.
(2022) Aging Cell, 21, 10, e13711

Brain-Restricted Inhibition of IL-6 Trans-Signaling Mildly Affects Metabolic Consequences of Maternal Obesity in Male Offspring

  • Breuer, S.
  • Kasper, P.
  • Vohlen, C.
  • Janoschek, R.
  • Hoffmann, T.
  • Appel, S.
  • Muller-Limberger, E.
  • Mesaros, A.
  • Rose-John, S.
  • Garbers, C.
  • Muller, S.
  • Lackmann, J. W.
  • Mahabir, E.
  • Dotsch, J.
  • Hucklenbruch-Rother, E.
  • Bae-Gartz, I.
(2021) Nutrients, 13, 11

Lithium can mildly increase health during ageing but not lifespan in mice

  • Nespital, T.
  • Neuhaus, B.
  • Mesaros, A.
  • Pahl, A.
  • Partridge, L.
(2021) Aging Cell, 10, 20, e13479

High levels of TFAM repress mammalian mitochondrial DNA transcription in vivo

  • Bonekamp, N. A.
  • Jiang, M.
  • Motori, E.
  • Garcia Villegas, R.
  • Koolmeister, C.
  • Atanassov, I.
  • Mesaros, A.
  • Park, C. B.
  • Larsson, N. G.
(2021) Life Sci Alliance, 4, 11, e202101034

Dnmt3a2/Dnmt3L Overexpression in the Dopaminergic System of Mice Increases Exercise Behavior through Signaling Changes in the Hypothalamus

  • Cui, D.
  • Mesaros, A.
  • Burdeos, G.
  • Voigt, I.
  • Giavalisco, P.
  • Hinze, Y.
  • Purrio, M.
  • Neumaier, B.
  • Drzezga, A.
  • Obata, Y.
  • Endepols, H.
  • Xu, X.
(2020) Int J Mol Sci, 21, 17, 6297

Hippocampal insulin resistance links maternal obesity with impaired neuronal plasticity in adult offspring

  • Schmitz, L.
  • Kuglin, R.
  • Bae-Gartz, I.
  • Janoschek, R.
  • Appel, S.
  • Mesaros, A.
  • Jakovcevski, I.
  • Vohlen, C.
  • Handwerk, M.
  • Ensenauer, R.
  • Dotsch, J.
  • Hucklenbruch-Rother, E.
(2017) Psychoneuroendocrinology, 89, 46-52

Matching Dietary Amino Acid Balance to the In Silico-Translated Exome Optimizes Growth and Reproduction without Cost to Lifespan

  • Piper, M. D.
  • Soultoukis, G. A.
  • Blanc, E.
  • Mesaros, A.
  • Herbert, S. L.
  • Juricic, P.
  • He, X.
  • Atanassov, I.
  • Salmonowicz, H.
  • Yang, M.
  • Simpson, S. J.
  • Ribeiro, C.
  • Partridge, L.
(2017) Cell Metab, 25, 3, 610-621

Cannabinoid receptor-interacting protein Crip1a modulates CB1 receptor signaling in mouse hippocampus

  • Guggenhuber, S.
  • Alpar, A.
  • Chen, R.
  • Schmitz, N.
  • Wickert, M.
  • Mattheus, T.
  • Harasta, A. E.
  • Purrio, M.
  • Kaiser, N.
  • Elphick, M. R.
  • Monory, K.
  • Kilb, W.
  • Luhmann, H. J.
  • Harkany, T.
  • Lutz, B.
  • Klugmann, M.
(2016) Brain Struct Funct, 221, 4, 2061-74

Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin

  • Mauer, J.
  • Chaurasia, B.
  • Goldau, J.
  • Vogt, M. C.
  • Ruud, J.
  • Nguyen, K. D.
  • Theurich, S.
  • Hausen, A. C.
  • Schmitz, J.
  • Bronneke, H. S.
  • Estevez, E.
  • Allen, T. L.
  • Mesaros, A.
  • Partridge, L.
  • Febbraio, M. A.
  • Chawla, A.
  • Wunderlich, F. T.
  • Bruning, J. C.
(2014) Nat Immunol, 15, 5, 423-30

Cannabinoid receptor 1 deficiency in a mouse model of Alzheimer's disease leads to enhanced cognitive impairment despite of a reduction in amyloid deposition

  • Stumm, C.
  • Hiebel, C.
  • Hanstein, R.
  • Purrio, M.
  • Nagel, H.
  • Conrad, A.
  • Lutz, B.
  • Behl, C.
  • Clement, A. B.
(2013) Neurobiol Aging, 34, 11, 2574-84

Biphasic effects of cannabinoids in anxiety responses: CB1 and GABA(B) receptors in the balance of GABAergic and glutamatergic neurotransmission

  • Rey, A. A.
  • Purrio, M.
  • Viveros, M. P.
  • Lutz, B.
(2012) Neuropsychopharmacology, 37, 12, 2624-34

Experimental analysis of risk factors for ulcerative dermatitis in mice

  • Neuhaus, B.
  • Niessen, C. M.
  • Mesaros, A.
  • Withers, D. J.
  • Krieg, T.
  • Partridge, L.
(2012) Exp Dermatol, 21, 9, 712-3

Role for insulin signaling in catecholaminergic neurons in control of energy homeostasis

  • Konner, A. C.
  • Hess, S.
  • Tovar, S.
  • Mesaros, A.
  • Sanchez-Lasheras, C.
  • Evers, N.
  • Verhagen, L. A.
  • Bronneke, H. S.
  • Kleinridders, A.
  • Hampel, B.
  • Kloppenburg, P.
  • Bruning, J. C.
(2011) Cell Metab, 13, 6, 720-8

Enhanced Stat3 activation in POMC neurons provokes negative feedback inhibition of leptin and insulin signaling in obesity

  • Ernst, M. B.
  • Wunderlich, C. M.
  • Hess, S.
  • Paehler, M.
  • Mesaros, A.
  • Koralov, S. B.
  • Kleinridders, A.
  • Husch, A.
  • Munzberg, H.
  • Hampel, B.
  • Alber, J.
  • Kloppenburg, P.
  • Bruning, J. C.
  • Wunderlich, F. T.
(2009) J Neurosci, 29, 37, 11582-93

Activation of Stat3 signaling in AgRP neurons promotes locomotor activity

  • Mesaros, A.
  • Koralov, S. B.
  • Rother, E.
  • Wunderlich, F. T.
  • Ernst, M. B.
  • Barsh, G. S.
  • Rajewsky, K.
  • Bruning, J. C.
(2008) Cell Metab, 7, 3, 236-48

Signal-dependent control of gluconeogenic key enzyme genes through coactivator-associated arginine methyltransferase 1

  • Krones-Herzig, A.
  • Mesaros, A.
  • Metzger, D.
  • Ziegler, A.
  • Lemke, U.
  • Bruning, J. C.
  • Herzig, S.
(2006) J Biol Chem, 281, 6, 3025-9