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February 2017

Date Event Place
06th February 2017
Monday,
03:00pm05:00pm
MPI

Automated Microscopy Workshop

Speaker: Frank Josten, Thomas Beetz (GER - ZEISS Microscopy)
Organizer: FACS & Imaging Core Facility (Max Planck Institute for Biology of Ageing)

Together with ZEISS, we host a workshop "Automated Microscopy" about their HCS microscope Celldiscoverer 7 and their slide scanner for brightfield and fluorescence Axio Scan.Z1. For both systems are hand-on demos possible. We will keep the HCS microscope until Feb 16 and the slide scanner until Feb 8.

Seminar room 2/3, Ground Floor
Joseph-Stelzmann-Str. 9b
D-50931 Cologne
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20th February 2017
Monday,
04:00pm05:00pm
CSA

Aging and rejuvenation of somatic stem cells

Speaker: Hartmut Geiger (GER)
Organizer: Adam Antebi (Max Planck Institut for biology of ageing)

There will be wine and cheese and the possibility for further discussion after the talk.

lecture hall
CECAD Research Center, ground floor
Joseph-Stelzmann-Str. 26
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22nd February 2017
Wednesday,
04:00pm05:00pm
MPI

Synthetic biochemistry in practice: RE3Volutionary Computational Design of symmetric protein building blocks

Speaker: Prof. Dr. Arnout Voet (Department of Chemistry, KU Leuven)
Organizer: Martin Graef (Max Planck Institute for Biology of Ageing)

The modular nature of the protein architectures suggests that proteins have evolved by the duplication and fusion of genetic fragments to give rise to modular, often symmetric protein architectures, which later diversified under the influence of evolutionary pressure. We have developed a computational protein design work-flow in which we REverse Engineer Evolution (hence RE3Volutionary) to create symmetrically self assembling functional protein building blocks.

Our computational protein design workflow has been successful for the design of different protein building blocks (Pizza with 6fold, Tako with 8 fold, Ika with 4fold and mitsuba with 3fold symmetry). These novel proteins are interesting synthetic proteins and serve multiple purposes. Using the Pizza protein we have demonstrated mathematical guided self-assembly according to the lowest common multiplier rule. Furthermore, Pizza-derived proteins are able to biomineralize nano crystals resulting in protein dimerization.

Other protein derivatives can be used as building blocks to create fibers, tubes and protein cages. These novel types of protein materials have a huge potential for applications in drug delivery, tissue engineering and biocatalysis.

 

Seminar room 2/3
Max Planck Institute for Biology of Ageing
Joseph-Stelzmann-Str. 9b
Cologne
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28th February 2017
Tuesday,
11:00am12:00pm
MPI

The human transcriptome across tissues and individuals

Speaker: Prof. Roderic Guigo (Center for Genomic Regulation (CRG))
Organizer: Jorge Boucas (Max Planck Institute for Biology of Ageing)

Roderic will talk about the pilot phase of the Genotype-Tissue Expression (GTEx) project which has produced RNASeq from 1,641 samples originated from up to 43 tissues from 175 post-mortem donors constituting therefore an unique resource to investigate the human transcriptome across tissues and individuals (of any age).

 

 

 

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Auditorium
Max Planck Institute for Biology of Ageing
Joseph-Stelzmann-Str., 9b
50931 Cologne
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