Publikationen

Serviceeinheit Phänotypisierung

Zeitschriftenartikel (27)

2026
Zeitschriftenartikel
Zhang, R.; Huetzen, M. A.; Binici, A.; Martín-Gago, P.; Gasper, R.; Rudashevskaya, E.; Liu, J.; Nagaraju, C.; Reckzeh, E. S.; Stuedle, A. S. T. et al.; Hopff, A.-S.; Mesaros, A.; Unger, A.; Thelen, M.; Janning, P.; Reinhardt, H. C.; Ziegler, S.; Jachimowicz, R. D.; Waldmann, H.: Targeting a Glutamic Acid in PDEδ with Fluoromethyl-Aryl Electrophiles Impairs K-Ras Signaling. Journal of Medicinal Chemistry 69, S. 964 - 981 (2026)
2025
Zeitschriftenartikel
Müller-Limberger, E.; Frederick, B.; Hansen, S.; Wohlfarth, M.; Kasper, P.; Janoschek, R.; Mahabir, E.; Fischer, P.; Mesaros, A.; Purrio, M. et al.; Quaas, A.; Alejandre Alcázar, M. A.; Dötsch, J.; Hucklenbruch-Rother, E.; Appel, S.: Metformin in Obese Pregnancy: Developmental Reprogramming of Offspring Liver and MASLD Risk by Age and Sex. Endocrinology (2025)
Zeitschriftenartikel
Malliou-Becher, M.-N.; Turnwald, E.-M.; Skupin, L.; Kretschmer, T.; Mesaros, A.; Purrio, M.; Wohlfarth, M.; Handwerk, M.; Kalis, S.; Gründermann, D. et al.; Dötsch, J.; Germeyer, A.; Appel, S.: Effect of metformin on the endometrial proteome of diet-induced obese mice. J Mol Endocrinol (2025)
Zeitschriftenartikel
Medeiros, T. C.; Ovciarikova, J.; Li, X.; Krüger, P.; Bartsch, T.; Reato, S.; Crow, J. C.; Tellez Sutterlin, M.; Martins Garcia, B.; Rais, I. et al.; Allmeroth, K.; Hartman, M. D.; Denzel, M.; Purrio, M.; Mesaros, A.; Leung, K.-Y.; Greene, N. D. E.; Sheiner, L.; Giavalisco, P.; Pernas, L.: Mitochondria protect against an intracellular pathogen by restricting access to folate. Science 389 (2025)
Zeitschriftenartikel
Miranda, M.; Mesaros, A.; Scrima, N.; Pérard, L.; Kuznetsova, I.; Purrio, M.; Atanassov, I.; Filipovska, A.; Mourier, A.; Larsson, N.-G. et al.; Kühl, I.: POLRMT overexpression increases mtDNA transcription without affecting steady-state mRNA levels. Life Science Alliance 8, S. e202302563 (2025)
2023
Zeitschriftenartikel
Baghdadi, M.; Mesaros, A.; Purrio, M.; Partridge, L.: Sex-specific effects of Cre expression in Syn1Cre mice. Scientific Reports 13, 10037 (2023)
Zeitschriftenartikel
Ripa, R.; Mesaros, A.; Symmons, O.; Ballhysa, E.; Dolfi, L.; Antebi, A.: Micro-CT Analysis of Fat in the Killifish Nothobranchius furzeri. Cold Spring Harb Protoc (2023)
Zeitschriftenartikel
Janoschek, R.; Handwerk, M.; Hucklenbruch-Rother, E.; Schmitz, L.; Bae-Gartz, I.; Kasper, P.; Lackmann, J.-W.; Kretschmer, T.; Vohlen, C.; Mesaros, A. et al.; Purrio, M.; Quaas, A.; Dötsch, J.; Appel, S.: Heterogeneous effects of individual high-fat diet compositions on phenotype, metabolic outcome, and hepatic proteome signature in BL/6 male mice. Nutr Metab (Lond) 20 (8) (2023)
Zeitschriftenartikel
Baghdadi, M.; Nespital, T.; Mesaros, A.; Buschbaum, S.; Withers, D. J.; Grönke, S.; Partridge, L.: Reduced insulin signaling in neurons induces sex-specific health benefits. Science Advances 9 (2023)
Zeitschriftenartikel
Milenkovic, D.; Misic, J.; Hevler, J. F.; Molinié, T.; Chung, I.; Atanassov, I.; Li, X.; Filograna, R.; Mesaros, A.; Mourier, A. et al.; Heck, A. J.R.; Hirst, J.; Larsson, N.-G.: Preserved respiratory chain capacity and physiology in mice with profoundly reduced levels of mitochondrial respirasomes. Cell Metabolism (2023)
2022
Zeitschriftenartikel
Srivastava, R. K.; Ruiz de Azua, I.; Conrad, A.; Purrio, M.; Lutz, B.: Cannabinoid CB1 Receptor Deletion from Catecholaminergic Neurons Protects from Diet-Induced Obesity. Int J Mol Sci 23 (20) (2022)
Zeitschriftenartikel
Allmeroth, K.; Hartman, M. D.; Purrio, M.; Mesaros, A.; Denzel, M. S.: Hexosamine pathway activation improves memory but does not extend lifespan in mice. Aging Cell, S. e13711 (2022)
2021
Zeitschriftenartikel
Breuer, S.; Kasper, P.; Vohlen, C.; Janoschek, R.; Hoffmann, T.; Appel, S.; Müller-Limberger, E.; Mesaros, A.; Rose-John, S.; Garbers, C. et al.; Müller, S.; Lackmann, J.-W.; Mahabir, E.; Dötsch, J.; Hucklenbruch-Rother, E.; Bae-Gartz, I.: Brain-Restricted Inhibition of IL-6 Trans-Signaling Mildly Affects Metabolic Consequences of Maternal Obesity in Male Offspring. Nutrients 13, S. 3735 (2021)
Zeitschriftenartikel
Nespital, T.; Neuhaus, B.; Mesaros, A.; Pahl, A.; Partridge, L.: Lithium can mildly increase health during ageing but not lifespan in mice. Aging Cell 10 (20), S. e13479 (2021)
Zeitschriftenartikel
Bonekamp, N.; Jiang, M.; Motori, E.; Garcia Villegas, R.; Koolmeister, C.; Atanassov, I.; Mesaros, A.; Park, C. B.; Larsson, N.G.: High levels of TFAM repress mammalian mitochondrial DNA transcription in vivo. Life Sci Alliance 4 (11), S. e202101034 (2021)
Zeitschriftenartikel
Pouikli, A.; Parekh, S.; Maleszewska, M.; Nikopoulou, C.; Baghdadi, M.; Tripodi, I.; Folz-Donahue, K.; Hinze, Y.; Mesaros, A.; Hoey, D. et al.; Giavalisco, P.; Dowell, R.; Partridge, L.; Tessarz, P.: Chromatin remodeling due to degradation of citrate carrier impairs osteogenesis of aged mesenchymal stem cells. Nature Aging 1 (9), S. 810 - 825 (2021)
2020
Zeitschriftenartikel
Cui, D.; Mesaros, A.; Burdeos, G.; Voigt, I.; Giavalisco, P.; Hinze, Y.; Purrio, M.; Neumaier, B.; Drzezga, A.; Obata, Y. et al.; Endepols, H.; Xu, X.: Dnmt3a2/Dnmt3L Overexpression in the Dopaminergic System of Mice Increases Exercise Behavior through Signaling Changes in the Hypothalamus. Int J Mol Sci 21 (17), S. 6297 (2020)
2017
Zeitschriftenartikel
Piper, M. D.; Soultoukis, G. A.; Blanc, E.; Mesaros, A.; Herbert, S. L.; Juricic, P.; He, X.; Atanassov, I.; Salmonowicz, H.; Yang, M. et al.; Simpson, S. J.; Ribeiro, C.; Partridge, L.: Matching Dietary Amino Acid Balance to the In Silico-Translated Exome Optimizes Growth and Reproduction without Cost to Lifespan. Cell Metab 25 (3), S. 610 - 621 (2017)
2016
Zeitschriftenartikel
Guggenhuber, S.; Alpar, A.; Chen, R.; Schmitz, N.; Wickert, M.; Mattheus, T.; Harasta, A. E.; Purrio, M.; Kaiser, N.; Elphick, M. R. et al.; Monory, K.; Kilb, W.; Luhmann, H. J.; Harkany, T.; Lutz, B.; Klugmann, M.: Cannabinoid receptor-interacting protein Crip1a modulates CB1 receptor signaling in mouse hippocampus. Brain Struct Funct 221 (4), S. 2061 - 74 (2016)
2014
Zeitschriftenartikel
Mauer, J.; Chaurasia, B.; Goldau, J.; Vogt, M. C.; Ruud, J.; Nguyen, K. D.; Theurich, S.; Hausen, A. C.; Schmitz, J.; Bronneke, H. S. et al.; Estevez, E.; Allen, T. L.; Mesaros, A.; Partridge, L.; Febbraio, M. A.; Chawla, A.; Wunderlich, F. T.; Bruning, J. C.: Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin. Nat Immunol 15 (5), S. 423 - 30 (2014)
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