Publikationen von T. Langer

Murru, S.; Hess, S.; Barth, E.; Almajan, E. R.; Schatton, D.; Hermans, S.; Brodesser, S.; Langer, T.; Kloppenburg, P.; Rugarli, E. I.: Astrocyte-specific deletion of the mitochondrial m-AAA protease reveals glial contribution to neurodegeneration. Glia 67 (8), S. 1526 - 1541 (2019)

Miliara, X.; Tatsuta, T.; Berry, J. L.; Rouse, S. L.; Solak, K.; Chorev, D. S.; Wu, D.; Robinson, C. V.; Matthews, S.; Langer, T.: Structural determinants of lipid specificity within Ups/PRELI lipid transfer proteins. Nat Commun 10 (1), S. 1130 (2019)

Rashid, T.; Nemazanyy, I.; Paolini, C.; Tatsuta, T.; Crespin, P.; Villeneuve, D.; Brodesser, S.; Benit, P.; Rustin, P.; Baraibar, M. A. et al.; Agbulut, O.; Olivier, A.; Protasi, F.; Langer, T.; Chrast, R.; Lonlay, P.; Foucauld, H.; Blaauw, B.; Pende, M.: Lipin1 deficiency causes sarcoplasmic reticulum stress and chaperone‐responsive myopathy. The EMBO Journal 38 (2019)

Richter, F.; Dennerlein, S.; Nikolov, M.; Jans, D. C.; Naumenko, N.; Aich, A.; MacVicar, T.; Linden, A.; Jakobs, S.; Urlaub, H. et al.; Langer, T.; Rehling, P.: ROMO1 is a constituent of the human presequence translocase required for YME1L protease import. J Cell Biol 218 (2), S. 598 - 614 (2018)

Patron, M.; Sprenger, H.-G.; Langer, T.: m-AAA proteases, mitochondrial calcium homeostasis and neurodegeneration. Cell Res 28 (3), S. 296 - 306 (2018)

Brandt, C.; Nolte, H.; Henschke, S.; Engström Ruud, L.; Awazawa, M.; Morgan, D. A.; Gabel, P.; Sprenger, H.-G.; Hess, M. E.; Günther, S. et al.; Langer, T.; Rahmouni, K.; Fenselau, H.; Krüger, M.; Brüning, J. C.: Food Perception Primes Hepatic ER Homeostasis via Melanocortin-Dependent Control of mTOR Activation. Cell 175, S. 1321 - 1335.e20 (2018)

Saita , S.; Tatsuta, T.; Lampe, P. A.; König , T.; Ohba, Y.; Langer, T.: PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria. The EMBO Journal 37 (2018)

Sprenger, H.-G.; Wani, G.; Hesseling, A.; Konig, T.; Patron, M.; MacVicar, T.; Ahola, S.; Wai, T.; Barth, E.; Rugarli, E. I. et al.; Bergami, M.; Langer, T.: Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy. EMBO Mol Med 11 (1), S. e9288 (2018)

Tatsuta, T.; Langer, T.: Prohibitins. Curr Biol 27 (13), S. R629 - R631 (2017)

Saita, S.; Nolte, H.; Fiedler, K. U.; Kashkar, H.; Venne, A. S.; Zahedi, R. P.; Kruger, M.; Langer, T.: PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis. Nat Cell Biol 19 (4), S. 318 - 328 (2017)

Tatsuta, T.; Langer, T.: Intramitochondrial phospholipid trafficking. Biochim Biophys Acta 1862 (1), S. 81 - 89 (2017)

Vukotic, M.; Nolte, H.; König, T.; Saita , S.; Ananjew, M.; Krüger, M.; Tatsuta, T.; Langer, T.: Acylglycerol Kinase Mutated in Sengers Syndrome Is a Subunit of the TIM22 Protein Translocase in Mitochondria. Molecular Cell 67, S. 471 - 483.e7 (2017)

Wang, S.; Jacquemyn, J.; Murru, S.; Martinelli, P.; Barth, E.; Langer, T.; Niessen, C. M.; Rugarli, E. I.: The Mitochondrial m-AAA Protease Prevents Demyelination and Hair Greying. PLoS Genet 12 (12), S. e1006463 (2016)

Wai, T.; Saita, S.; Nolte, H.; Muller, S.; Konig, T.; Richter-Dennerlein, R.; Sprenger, H.-G.; Madrenas, J.; Muhlmeister, M.; Brandt, U. et al.; Kruger, M.; Langer, T.: The membrane scaffold SLP2 anchors a proteolytic hub in mitochondria containing PARL and the i-AAA protease YME1L. EMBO Rep 17 (12), S. 1844 - 1856 (2016)

Koenig, T.; Troder, S. E.; Bakka, K.; Korwitz, A.; Richter-Dennerlein, R.; Lampe, P. A.; Patron, M.; Muhlmeister, M.; Guerrero-Castillo, S.; Brandt, U. et al.; Decker, T.; Lauria, I.; Paggio, A.; Rizzuto, R.; Rugarli, E. I.; De Stefani, D.; Langer, T.: The m-AAA Protease Associated with Neurodegeneration Limits MCU Activity in Mitochondria. Mol Cell 64 (1), S. 148 - 162 (2016)

Tatsuta, T.; Langer, T.: Intramitochondrial phospholipid trafficking. Biochim Biophys Acta 1862 (1), S. 81 - 89 (2016)

Hartmann, B.; Wai, T.; Hu, H.; MacVicar, T.; Musante, L.; Fischer-Zirnsak, B.; Stenzel, W.; Graf, R.; van den Heuvel, L.; Ropers, H. H. et al.; Wienker, T. F.; Hubner, C.; Langer, T.; Kaindl, A. M.: Homozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network fragmentation. Elife 5 (2016)

Aaltonen, M. J.; Friedman, J. R.; Osman, C.; Salin, B.; di Rago, J. P.; Nunnari, J.; Langer, T.; Tatsuta, T.: MICOS and phospholipid transfer by Ups2-Mdm35 organize membrane lipid synthesis in mitochondria. J Cell Biol 213 (5), S. 525 - 34 (2016)

Mandel, H.; Saita, S.; Edvardson, S.; Jalas, C.; Shaag, A.; Goldsher, D.; Vlodavsky, E.; Langer, T.; Elpeleg, O.: Deficiency of HTRA2/Omi is associated with infantile neurodegeneration and 3-methylglutaconic aciduria. J Med Genet 53 (10), S. 690 - 6 (2016)

MacVicar, T.; Langer, T.: OPA1 processing in cell death and disease - the long and short of it. J Cell Sci 129 (12), S. 2297 - 306 (2016)