Serviceeinheit CRISPR screening

Publikationen

A Flexible, Pooled CRISPR Library for Drug Development Screens

  • Blanck, M.
  • Budnik-Zawilska, M. B.
  • Lenger, S. R.
  • McGonigle, J. E.
  • Martin, G. R. A.
  • le Sage, C.
  • Lawo, S.
  • Pemberton, H. N.
  • Tiwana, G. S.
  • Sorrell, D. A.
  • Cross, B. C. S.
(2020) Crispr j, 3(3): 211-222

CRISPR: A Screener's Guide

  • le Sage, C.
  • Lawo, S.
  • Cross, B. C. S.
(2020) SLAS Discov, 25, 3, 233-240

Dual direction CRISPR transcriptional regulation screening uncovers gene networks driving drug resistance

  • le Sage, C.
  • Lawo, S.
  • Panicker, P.
  • Scales, T. M. E.
  • Rahman, S. A.
  • Little, A. S.
  • McCarthy, N. J.
  • Moore, J. D.
  • Cross, B. C. S.
(2017) Sci Rep, 7, 1, 17693

Increasing the performance of pooled CRISPR-Cas9 drop-out screening

  • Cross, B. C.
  • Lawo, S.
  • Archer, C. R.
  • Hunt, J. R.
  • Yarker, J. L.
  • Riccombeni, A.
  • Little, A. S.
  • McCarthy, N. J.
  • Moore, J. D.
(2016) Sci Rep, 6, 31782

A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities

  • Vizeacoumar, F. J.
  • Arnold, R.
  • Vizeacoumar, F. S.
  • Chandrashekhar, M.
  • Buzina, A.
  • Young, J. T.
  • Kwan, J. H.
  • Sayad, A.
  • Mero, P.
  • Lawo, S.
  • Tanaka, H.
  • Brown, K. R.
  • Baryshnikova, A.
  • Mak, A. B.
  • Fedyshyn, Y.
  • Wang, Y.
  • Brito, G. C.
  • Kasimer, D.
  • Makhnevych, T.
  • Ketela, T.
  • Datti, A.
  • Babu, M.
  • Emili, A.
  • Pelletier, L.
  • Wrana, J.
  • Wainberg, Z.
  • Kim, P. M.
  • Rottapel, R.
  • O'Brien, C. A.
  • Andrews, B.
  • Boone, C.
  • Moffat, J.
(2013) Mol Syst Biol, 9, 696

CEP120 and SPICE1 cooperate with CPAP in centriole elongation

  • Comartin, D.
  • Gupta, G. D.
  • Fussner, E.
  • Coyaud, E.
  • Hasegan, M.
  • Archinti, M.
  • Cheung, S. W.
  • Pinchev, D.
  • Lawo, S.
  • Raught, B.
  • Bazett-Jones, D. P.
  • Luders, J.
  • Pelletier, L.
(2013) Curr Biol, 23, 14, 1360-6

Subdiffraction imaging of centrosomes reveals higher-order organizational features of pericentriolar material

  • Lawo, S.
  • Hasegan, M.
  • Gupta, G. D.
  • Pelletier, L.
(2012) Nat Cell Biol, 14, 11, 1148-58

Systematic analysis of human protein complexes identifies chromosome segregation proteins

  • Hutchins, J. R.
  • Toyoda, Y.
  • Hegemann, B.
  • Poser, I.
  • Heriche, J. K.
  • Sykora, M. M.
  • Augsburg, M.
  • Hudecz, O.
  • Buschhorn, B. A.
  • Bulkescher, J.
  • Conrad, C.
  • Comartin, D.
  • Schleiffer, A.
  • Sarov, M.
  • Pozniakovsky, A.
  • Slabicki, M. M.
  • Schloissnig, S.
  • Steinmacher, I.
  • Leuschner, M.
  • Ssykor, A.
  • Lawo, S.
  • Pelletier, L.
  • Stark, H.
  • Nasmyth, K.
  • Ellenberg, J.
  • Durbin, R.
  • Buchholz, F.
  • Mechtler, K.
  • Hyman, A. A.
  • Peters, J. M.
(2010) Science, 328, 5978, 593-9

HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity

  • Lawo, S.
  • Bashkurov, M.
  • Mullin, M.
  • Ferreria, M. G.
  • Kittler, R.
  • Habermann, B.
  • Tagliaferro, A.
  • Poser, I.
  • Hutchins, J. R.
  • Hegemann, B.
  • Pinchev, D.
  • Buchholz, F.
  • Peters, J. M.
  • Hyman, A. A.
  • Gingras, A. C.
  • Pelletier, L.
(2009) Curr Biol, 19, 10, 816-26

The mammalian SPD-2 ortholog Cep192 regulates centrosome biogenesis

  • Zhu, F.
  • Lawo, S.
  • Bird, A.
  • Pinchev, D.
  • Ralph, A.
  • Richter, C.
  • Muller-Reichert, T.
  • Kittler, R.
  • Hyman, A. A.
  • Pelletier, L.
(2008) Curr Biol, 18, 2, 136-41

Genome-scale RNAi profiling of cell division in human tissue culture cells

  • Kittler, R.
  • Pelletier, L.
  • Heninger, A. K.
  • Slabicki, M.
  • Theis, M.
  • Miroslaw, L.
  • Poser, I.
  • Lawo, S.
  • Grabner, H.
  • Kozak, K.
  • Wagner, J.
  • Surendranath, V.
  • Richter, C.
  • Bowen, W.
  • Jackson, A. L.
  • Habermann, B.
  • Hyman, A. A.
  • Buchholz, F.
(2007) Nat Cell Biol, 9, 12, 1401-12

The Drosophila mitotic inhibitor Fruhstart specifically binds to the hydrophobic patch of cyclins

  • Gawlinski, P.
  • Nikolay, R.
  • Goursot, C.
  • Lawo, S.
  • Chaurasia, B.
  • Herz, H. M.
  • Kussler-Schneider, Y.
  • Ruppert, T.
  • Mayer, M.
  • Grosshans, J.
(2007) EMBO Rep, 8, 5, 490-6

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