Publikationen von T. Langer

Rugarli, E. I.; Langer, T.: Mitochondrial quality control: a matter of life and death for neurons. EMBO J 31 (6), S. 1336 - 49 (2012)

Pierson, T. M.; Adams, D.; Bonn, F.; Martinelli, P.; Cherukuri, P. F.; Teer, J. K.; Hansen, N. F.; Cruz, P.; Mullikin For The Nisc Comparative Sequencing Program, J. C.; Blakesley, R. W. et al.; Golas, G.; Kwan, J.; Sandler, A.; Fuentes Fajardo, K.; Markello, T.; Tifft, C.; Blackstone, C.; Rugarli, E. I.; Langer, T.; Gahl, W. A.; Toro, C.: Whole-exome sequencing identifies homozygous AFG3L2 mutations in a spastic ataxia-neuropathy syndrome linked to mitochondrial m-AAA proteases. PLoS Genet 7 (10), S. e1002325 (2011)

Gerdes, F.; Tatsuta, T.; Langer, T.: Mitochondrial AAA proteases--towards a molecular understanding of membrane-bound proteolytic machines. Biochim Biophys Acta 1823 (1), S. 49 - 55 (2011)

Baris, O. R.; Klose, A.; Kloepper, J. E.; Weiland, D.; Neuhaus, J. F.; Schauen, M.; Wille, A.; Muller, A.; Merkwirth, C.; Langer, T. et al.; Larsson, N. G.; Krieg, T.; Tobin, D. J.; Paus, R.; Wiesner, R. J.: The mitochondrial electron transport chain is dispensable for proliferation and differentiation of epidermal progenitor cells. Stem Cells 29 (9), S. 1459 - 68 (2011)

Baker, M. J.; Tatsuta, T.; Langer, T.: Quality control of mitochondrial proteostasis. Cold Spring Harb Perspect Biol 3 (7) (2011)

Alikhani, N.; Berglund, A. K.; Engmann, T.; Spanning, E.; Vogtle, F. N.; Pavlov, P.; Meisinger, C.; Langer, T.; Glaser, E.: Targeting capacity and conservation of PreP homologues localization in mitochondria of different species. J Mol Biol 410 (3), S. 400 - 10 (2011)

Bonn, F.; Tatsuta, T.; Petrungaro, C.; Riemer, J.; Langer, T.: Presequence-dependent folding ensures MrpL32 processing by the m-AAA protease in mitochondria. EMBO J 30 (13), S. 2545 - 56 (2011)

Anton, F.; Fres, J. M.; Schauss, A.; Pinson, B.; Praefcke, G. J.; Langer, T.; Escobar-Henriques, M.: Ugo1 and Mdm30 act sequentially during Fzo1-mediated mitochondrial outer membrane fusion. J Cell Sci 124 (Pt 7), S. 1126 - 35 (2011)

Osman, C.; Voelker, D. R.; Langer, T.: Making heads or tails of phospholipids in mitochondria. J Cell Biol 192 (1), S. 7 - 16 (2011)

Morimoto, R. I.; Driessen, A. J.; Hegde, R. S.; Langer, T.: The life of proteins: the good, the mostly good and the ugly. Nat Struct Mol Biol 18 (1), S. 1 - 4 (2011)

Lee, S.; Augustin, S.; Tatsuta, T.; Gerdes, F.; Langer, T.; Tsai, F. T.: Electron cryomicroscopy structure of a membrane-anchored mitochondrial AAA protease. J Biol Chem 286 (6), S. 4404 - 11 (2010)

Brüning, J.; Langer, T.; Trifunovic, A.: Highlight: The biology of aging: mechanisms and intervention. Biol Chem 391 (10), S. 1113 (2010)

Potting, C.; Wilmes, C.; Engmann, T.; Osman, C.; Langer, T.: Regulation of mitochondrial phospholipids by Ups1/PRELI-like proteins depends on proteolysis and Mdm35. EMBO J 29 (17), S. 2888 - 98 (2010)

Osman, C.; Haag, M.; Wieland, F. T.; Brugger, B.; Langer, T.: A mitochondrial phosphatase required for cardiolipin biosynthesis: the PGP phosphatase Gep4. EMBO J 29 (12), S. 1976 - 87 (2010)

Di Bella, D.; Lazzaro, F.; Brusco, A.; Plumari, M.; Battaglia, G.; Pastore, A.; Finardi, A.; Cagnoli, C.; Tempia, F.; Frontali, M. et al.; Veneziano, L.; Sacco, T.; Boda, E.; Brussino, A.; Bonn, F.; Castellotti, B.; Baratta, S.; Mariotti, C.; Gellera, C.; Fracasso, V.; Magri, S.; Langer, T.; Plevani, P.; Di Donato, S.; Muzi-Falconi, M.; Taroni, F.: Mutations in the mitochondrial protease gene AFG3L2 cause dominant hereditary ataxia SCA28. Nat Genet 42 (4), S. 313 - 21 (2010)

Bonn, F.; Pantakani, K.; Shoukier, M.; Langer, T.; Mannan, A. U.: Functional evaluation of paraplegin mutations by a yeast complementation assay. Hum Mutat 31 (5), S. 617 - 21 (2010)

Ehses, S.; Raschke, I.; Mancuso, G.; Bernacchia, A.; Geimer, S.; Tondera, D.; Martinou, J. C.; Westermann, B.; Rugarli, E. I.; Langer, T.: Regulation of OPA1 processing and mitochondrial fusion by m-AAA protease isoenzymes and OMA1. J Cell Biol 187 (7), S. 1023 - 36 (2009)

Osman, C.; Merkwirth, C.; Langer, T.: Prohibitins and the functional compartmentalization of mitochondrial membranes. J Cell Sci 122 (Pt 21), S. 3823 - 30 (2009)

Tatsuta, T.; Langer, T.: AAA proteases in mitochondria: diverse functions of membrane-bound proteolytic machines. Res Microbiol 160 (9), S. 711 - 7 (2009)

Augustin, S.; Gerdes, F.; Lee, S.; Tsai, F. T.; Langer, T.; Tatsuta, T.: An intersubunit signaling network coordinates ATP hydrolysis by m-AAA proteases. Mol Cell 35 (5), S. 574 - 85 (2009)