Fitzian, K.; Bruckner, A.; Brohée, L.; Zech, R.; Antoni, C.; Kiontke, S.; Gasper, R.; Linard Matos, A. L.; Beel, S.; Wilhelm, S. et al.; Gerke, V.; Ungermann, C.; Nellist, M.; Raunser, S.; Demetriades, C.; Oeckinghaus, A.; Kummel, D.: TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation. Mol Cell 81 (13), S. 2705 - 2721 (2021)

Sieben, A.; Hausen, A. C.; Klemm, P.; Jais, A.; Heilinger, C.; Alber, J.; Folz-Donahue, K.; Schumacher, L.; Altmüller, J.; Franitza, M. et al.; Giavalisco, P.; Hinze, Y.; Brodesser, S.; Kukat, C.; Theurich, S.; Brüning, J. C.: P2Y6 receptor signaling in natural killer cells impairs insulin sensitivity in obesity. bioRxiv, S. 2021.06.23.449596 (2021)

Gassen, N. C.; Papies, J.; Bajaj, T.; Emanuel, J.; Dethloff, F.; Chua, R. L.; Trimpert, J.; Heinemann, N.; Niemeyer, C.; Weege, F. et al.; Honzke, K.; Aschman, T.; Heinz, D. E.; Weckmann, K.; Ebert, T.; Zellner, A.; Lennarz, M.; Wyler, E.; Schroeder, S.; Richter, A.; Niemeyer, D.; Hoffmann, K.; Meyer, T. F.; Heppner, F. L.; Corman, V. M.; Landthaler, M.; Hocke, A. C.; Morkel, M.; Osterrieder, N.; Conrad, C.; Eils, R.; Radbruch, H.; Giavalisco, P.; Drosten, C.; Muller, M. A.: SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals. Nat Commun 12 (1), S. 3818 (2021)

Murschall, L. M.; Peker, E.; MacVicar, T.; Langer, T.; Riemer, J.: Protein Import Assay into Mitochondria Isolated from Human Cells. Bio Protoc 11 (12), S. e4057 (2021)

Ignatov, T.; Gaßner, J.; Bozukova, M.; Ivros, S.; Mészáros, J.; Ortmann, O.; Eggemann, H.; Ignatov, A.: Contralateral lymph node metastases in patients with vulvar cancer and unilateral sentinel lymph node metastases. Acta Obstet Gynecol Scand 100 (8), S. 1520 - 1525 (2021)

Theobald, S. J.; Simonis, A.; Georgomanolis, T.; Kreer, C.; Zehner, M.; Eisfeld, H. S.; Albert, M. C.; Chhen, J.; Motameny, S.; Erger, F. et al.; Fischer, J.; Malin, J. J.; Gräb, J.; Winter, S.; Pouikli, A.; David, F.; Böll, B.; Koehler, P.; Vanshylla, K.; Gruell, H.; Suárez, I.; Hallek, M.; Fätkenheuer, G.; Jung, N.; Cornely, O. A.; Lehmann, C.; Tessarz, P.; Altmüller, J.; Nürnberg, P.; Kashkar, H.; Klein, F.; Koch, M.; Rybniker, J.: Long-lived macrophage reprogramming drives spike protein-mediated inflammasome activation in COVID-19. EMBO Mol Med 8 (13), S. e14150 (2021)

Cipullo, M.; Gese, G. V.; Khawaja, A.; Hallberg, B. M.; Rorbach, J.: Structural basis for late maturation steps of the human mitoribosomal large subunit. Nat Commun 12 (1), S. 3673 (2021)

Jachimowicz, R. D.; Klapper, W.; Glehr, G.; Muller, H.; Haverkamp, H.; Thorns, C.; Hansmann, M. L.; Moller, P.; Stein, H.; Rehberg, T. et al.; von Tresckow, B.; Reinhardt, H. C.; Borchmann, P.; Chan, F. C.; Spang, R.; Scott, D. W.; Engert, A.; Steidl, C.; Altenbuchinger, M.; Rosenwald, A.: Gene expression-based outcome prediction in advanced stage classical Hodgkin lymphoma treated with BEACOPP. Leukemia 35 (12), S. 3589 - 3593 (2021)

Annibal, A.; Tharyan, R. G.; Schonewolff, M. F.; Tam, H.; Latza, C.; Auler, M. M. K.; Grönke, S.; Partridge, L.; Annibal, A.: Regulation of the one carbon folate cycle as a shared metabolic signature of longevity. Nat Commun 12 (1), S. 3486 (2021)

Wang, W.; van Dijk, K. W.; Wijsman, C. A.; Rozing, M. P.; Mooijaart, S. P.; Beekman, M.; Slagboom, P. E.; Jukema, J. W.; Noordam, R.; van Heemst, D.: Differential insulin sensitivity of NMR-based metabolomic measures in a two-step hyperinsulinemic euglycemic clamp study. Metabolomics 17 (6), S. 57 (2021)

Miroshnikova, Y. A.; Manet, S.; Li, X.; Wickström, S. A.; Faurobert, E.; Albiges-Rizo, C.: Calcium signaling mediates a biphasic mechanoadaptive response of endothelial cells to cyclic mechanical stretch. Mol Biol Cell 32 (18), S. 1724 - 1736 (2021)

Zekonyte, U.; Bacman, S. R.; Smith, J.; Shoop, W.; Pereira, C. V.; Tomberlin, G.; Stewart, J.; Jantz, D.; Moraes, C. T.: Mitochondrial targeted meganuclease as a platform to eliminate mutant mtDNA in vivo. Nat Commun 12 (1), S. 3210 (2021)

Trela, E.; Lan, Q.; Myllymäki, S. M.; Villeneuve, C.; Lindström, R.; Kumar, V.; Wickström, S. A.; Mikkola, M. L.: Cell influx and contractile actomyosin force drive mammary bud growth and invagination. J Cell Biol 220 (8) (2021)

Klaric, J. A.; Wüst, S.; Panier, S.: New Faces of old Friends: Emerging new Roles of RNA-Binding Proteins in the DNA Double-Strand Break Response. Front Mol Biosci 8, S. 668821 (2021)

Cretin, E.; Lopes, P.; Vimont, E.; Tatsuta, T.; Langer, T.; Gazi, A.; Sachse, M.; Yu-Wai-Man, P.; Reynier, P.; Wai, T.: High-throughput screening identifies suppressors of mitochondrial fragmentation in OPA1 fibroblasts. EMBO Mol Med 13 (6), S. e13579 (2021)

Cui, R.; Tyers, A. M.; Malubhoy, Z. J.; Wisotsky, S.; Valdesalici, S.; Henriette, E.; Kosakovsky Pond, S. L.; Valenzano, D. R.: Ancestral transoceanic colonization and recent population reduction in a non-annual killifish from the Seychelles archipelago. Mol Ecol 30 (14), S. 3610 - 2623 (2021)

Fabian, D. K.; Fuentealba, M.; Donertas, H. M.; Partridge, L.; Thornton, J. M.: Functional conservation in genes and pathways linking ageing and immunity. Immun Ageing 18 (1), S. 23 (2021)

Lu, Y.-X.; Regan, J. C.; Esser, J.; Drews, L. F.; Weinseis, T.; Stinn, J.; Hahn, O.; Miller, R. A.; Grönke, S.; Partridge, L.: A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageing. Elife 10 (2021)

Dzankic, P. J.; Partridge, L.: Clinical trials of mTOR inhibitors to boost immunity to viral infection in older adults. Lancet Healthy Longev 2 (5), S. e232 - e233 (2021)

Niccoli, T.; Kerr, F.; Snoeren, I.; Fabian, D.; Aleyakpo, B.; Ivanov, D.; Sofola-Adesakin, O.; Cryar, A.; Adcott, J.; Thornton, J. et al.; Partridge, L.: Activating transcription factor 4-dependent lactate dehydrogenase activation as a protective response to amyloid beta toxicity. Brain Commun 3 (2), S. fcab053 (2021)