Publications

Morón-Oset, J.; Fischer, L. K. S.; Jauré, N.; Zhang, P.; Jahn, A. J.; Supèr, T.; Pahl, A.; Isaacs, A. M.; Grönke, S.; Partridge, L.: Repeat length of C9orf72-associated glycine–alanine polypeptides affects their toxicity. Acta Neuropathologica Communications 11, 140 (2023)

Chawla, S.; Ahmadpour, D.; Schneider, K. L.; Kumar, N.; Fischbach, A.; Molin, M.; Nystrom, T.: Calcineurin stimulation by Cnb1p overproduction mitigates protein aggregation and α-synuclein toxicity in a yeast model of synucleinopathy. Cell Communication and Signaling 21, 220 (2023)

Popescu, I.; Deelen, J.; Illario, M.; Adams, J.: Challenges in anti‐aging medicine–trends in biomarker discovery and therapeutic interventions for a healthy lifespan. Journal of Cellular and Molecular Medicine (2023)

Tschernoster, N.; Erger, F.; Kohl, S.; Reusch, B.; Wenzel, A.; Walsh, S.; Thiele, H.; Becker, C.; Franitza, M.; Bartram, M. P. et al.; Kömhoff, M.; Schumacher, A. L.; Kukat, C.; Borodina, T.; Quedenau, C.; Nürnberg, P.; Rinschen, M. M.; Driller, J. H.; Pedersen, B. P.; Schlingmann, K. P.; Hüttel, B.; Bockenhauer, D.; Beck, B.; Altmüller, J.: Long-read sequencing identifies a common transposition haplotype predisposing for CLCNKB deletions. Genome Medicine 15, 62 (2023)

Nicastro , R.; Brohée, L.; Alba, J.; Nuechel, J.; Figlia, G.; Kipschull, S.; Gollwitzer, P.; Romero-Pozuelo, J.; Fernandes, S. A.; Lamprakis, A. et al.; Vanni, S.; Teleman, A. A.; De Virgilio, C.; Demetriades, C.: Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitor. Nature Cell Biology (2023)

van den Berg, N.; Rodríguez-Girondo, M.; van Dijk, I. K.; Slagboom, P. E.; Beekman, M.: Increasing number of long-lived ancestors marks a decade of healthspan extension and healthier metabolomics profiles. Nature Communications 14, 4518 (2023)

Sawant, M.; Wang, F.; Koester, J.; Niehoff, A.; Nava, M. M.; Lundgren-Akerlund, E.; Gullberg, D.; Leitinger, B.; Wickström, S. A.; Eckes, B. et al.; Krieg, T.: Ablation of integrin-mediated cell–collagen communication alleviates fibrosis. Annals of the Rheumatic Diseases, p. ard-2023-224129 (2023)

Grotehans, N.; McGarry, L.; Nolte, H.; Xavier, V.; Kroker, M.; Narbona-Pérez, Á. J.; Deshwal, S.; Giavalisco, P.; Langer, T.; MacVicar, T.: Ribonucleotide synthesis byNME6fuels mitochondrial gene expression. The EMBO Journal (2023)

Aarabi, F.; Salem, M. A.; Arrivault, S.; Bulut, M.; Schöttler, M. A.; Giavalisco, P.; Fernie, A. R.; Hoefgen, R.: The regulation of sulfolipids under sulfur starvation. Plant Molecular Biology (2023)

Kim, E.; Annibal, A.; Lee, Y.; Park, H.-E. H.; Ham, S.; Jeong, D.-E.; Kim, Y.; Park, S.; Kwon, S.; Jung, Y. et al.; Park, J.; Kim, S. S.; Antebi, A.; Lee, S.-J. V.: Mitochondrial aconitase suppresses immunity by modulating oxaloacetate and the mitochondrial unfolded protein response. Nature Communications 14, 3716 (2023)

Longarini, E. J.; Dauben, H.: Deciphering ADP-ribosylation signalling. Nature Reviews Molecular Cell Biology (2023)

Baghdadi, M.; Mesaros, A.; Purrio, M.; Partridge, L.: Sex-specific effects of Cre expression in Syn1Cre mice. Scientific Reports 13, 10037 (2023)

Kim, J. Y.; Atanassov, I.; Dethloff, F.; Kroczek, L.; Langer, T.: Time-resolved proteomic analyses of senescence highlight metabolic rewiring of mitochondria. Life science alliance 6 (9), e202302127 (2023)

Artoni, F.; Grützmacher, N.; Demetriades, C.: Unbiased evaluation of rapamycin's specificity as an mTOR inhibitor. Aging Cell (2023)

Suzuki, T.; Chéret, J.; Scala, F. D.; Akhundlu, A.; Gherardini, J.; Demetrius, D.; O'Sullivan, J. D. B.; Kuka Epstein, G.; Bauman, A. J.; Demetriades, C. et al.; Paus, R.: mTORC1 activity negatively regulates human hair follicle growth and pigmentation. EMBO reports (2023)

Fischbach, A.; Johns, A.; Schneider, K. L.; Hao, X.; Tessarz, P.; Nyström, T.: Artificial Hsp104-mediated systems for re-localizing protein aggregates. Nature Communications 14, 2663 (2023)

Montoro-Gámez, C.; Nolte, H.; Molinié, T.; Evangelista, G.; Tröder, S.; Barth, E.; Popovic, M.; Trifunovic, A.; Zevnik, B.; Langer, T. et al.; Rugarli, E. I.: SARM1 deletion delays cerebellar but not spinal cord degeneration in an enhanced mouse model ofSPG7deficiency. Brain (2023)

Debès, C.; Papadakis, A.; Grönke, S.; Karalay, O.; Tain, L. S.; Mizi, A.; Nakamura, S.; Hahn, O.; Weigelt, C. M.; Josipovic, N. et al.; Zirkel, A.; Brusius, I.; Sofiadis, K.; Lamprousi, M.; Lu, Y.-X.; Huang, W.; Esmaillie, R.; Kubacki, T.; Späth, M. R.; Schermer, B.; Benzing, T.; Müller, R.-U.; Antebi, A.; Partridge, L.; Papantonis, A.; Beyer, A.: Ageing-associated changes in transcriptional elongation influence longevity. Nature (2023)

Perez-Perri, J. I.; Ferring-Appel, D.; Huppertz, I.; Schwarzl, T.; Sahadevan, S.; Stein, F.; Rettel, M.; Galy, B.; Hentze, M. W.: The RNA-binding protein landscapes differ between mammalian organs and cultured cells. Nature Communications 14, 2074 (2023)

Gaudreault, N.; Ali, R.; Avilov, S. V.; Bagley, S.; Bammann, R. R.; Barachati, F.; Barna, L.; Berno, V.; Bertocchi, C.; Boczonadi, V. et al.; Boehm, U.; Bosch, M.; Brideau, C.; Carvalho, N.; Chatterjee, N.; Colarusso, P.; Cole, R.; Darwish-Miranda, N.; Dervish, S.; Dietzel, R.; Duwé, S.; Eismann, F.; Faklaris, O.; Felscher, A.; Ferdous, Z.; Guilbert, T.; Gonnert, M.; Grunwald, D.; Hoffmann, B.; Kirchner, M.; Krens, G.; Laude, A. J.; LeDue, J. M.; Liu, P.; Lorentz, P.; Martins, G. G.; Mezzana Robinson, V.; Mitovski, M.; Nelson, M. S.; Nitschke, R.; Payne-Dwyer, A. L.; Pimente Cabrera, J. A.; Podder, S.; Schroth-Diez, B.; Schwartz, S.; Srinivasan, S.; Theunauer, R.; van der Oord, K.; Taatjes, D. J.; van Oostende-Triplet, C.; Wee, T.-L.; Weiss, K. R.; Gelman, L.: lllumination Power, Stability, and Linearity Measurements for Confocal and Widefield Microscopes V.2. protocols.io (2023)