Publikationen Abteilung Antebi

Mass spectrometric characterization of cyclic dinucleotides (CDNs) in vivo

  • Annibal, A.
  • Ripa, R.
  • Ballhysa, E.
  • Latza, C.
  • Hochhard, N.
  • Antebi, A.
(2021) Anal Bioanal Chem

Sperm cryopreservation and in vitro fertilization techniques for the African turquoise killifish Nothobranchius furzeri

  • Dolfi, L.
  • Suen, T. K.
  • Ripa, R.
  • Antebi, A.
(2021) Sci Rep, 11, 1, 17145

miR-1 coordinately regulates lysosomal v-ATPase and biogenesis to impact proteotoxicity and muscle function during aging

  • Schiffer, I.
  • Gerisch, B.
  • Kawamura, K.
  • Laboy, R.
  • Hewitt, J.
  • Denzel, M. S.
  • Mori, M. A.
  • Vanapalli, S.
  • Shen, Y.
  • Symmons, O.
  • Antebi, A.
(2021) Elife, 10

Regulation of the one carbon folate cycle as a shared metabolic signature of longevity

  • Annibal, A.
  • Tharyan, R. G.
  • Schonewolff, M. F.
  • Tam, H.
  • Latza, C.
  • Auler, M. M. K.
  • Gronke, S.
  • Partridge, L.
  • Antebi, A.
(2021) Nat Commun, 12, 1, 3486

N1-acetylspermidine is a determinant of hair follicle stem cell fate

  • Allmeroth, K.
  • Kim, C. S.
  • Annibal, A.
  • Pouikli, A.
  • Koester, J.
  • Derisbourg, M. J.
  • Andres Chacon-Martinez, C.
  • Latza, C.
  • Antebi, A.
  • Tessarz, P.
  • Wickstrom, S. A.
  • Denzel, M. S.
(2021) J Cell Sci, 134, 9

Mitochondrial hydrogen sulfide supplementation improves health in the C. elegans Duchenne muscular dystrophy model

  • Ellwood, R. A.
  • Hewitt, J. E.
  • Torregrossa, R.
  • Philp, A. M.
  • Hardee, J. P.
  • Hughes, S.
  • van de Klashorst, D.
  • Gharahdaghi, N.
  • Anupom, T.
  • Slade, L.
  • Deane, C. S.
  • Cooke, M.
  • Etheridge, T.
  • Piasecki, M.
  • Antebi, A.
  • Lynch, G. S.
  • Philp, A.
  • Vanapalli, S. A.
  • Whiteman, M.
  • Szewczyk, N. J.
(2021) Proc Natl Acad Sci U S A, 118, 9

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

  • Klionsky, D. J., (…)
  • Antebi, A., (…)
  • Graef, M., (…)
  • Brand-Saberi, B.
  • Dong, X. C.
  • Kenchappa, C. S.
  • Li, Z.
  • Lin, Y.
  • Oshima, S.
  • Rong, Y.
  • Sluimer, J. C.
  • Stallings, C. L.
  • Tong, C. K.
(2021) Autophagy, 1-382

Identification of a Novel Link between the Intermediate Filament Organizer IFO-1 and Cholesterol Metabolism in the Caenorhabditis elegans Intestine

  • A. Coch R
  • Geisler, F.
  • Annibal, A.
  • Antebi, A.
  • E. Leube R
(2020) Int J Mol Sci, 21, 21

Identification of a Novel Link between the Intermediate Filament Organizer IFO-1 and Cholesterol Metabolism in the Caenorhabditis elegans Intestine

  • Coch, R. A.
  • Geisler, F.
  • Annibal, A.
  • Antebi, A.
  • Leube, R. E.
(2020) Int J Mol Sci, 21, 21

Polyunsaturated fatty acids and p38-MAPK link metabolic reprogramming to cytoprotective gene expression during dietary restriction

  • Chamoli, M.
  • Goyala, A.
  • Tabrez, S. S.
  • Siddiqui, A. A.
  • Singh, A.
  • Antebi, A.
  • Lithgow, G. J.
  • Watts, J. L.
  • Mukhopadhyay, A.
(2020) Nat Commun, 11, 1, 4865

NFYB-1 regulates mitochondrial function and longevity via lysosomal prosaposin

  • Tharyan, R. G.
  • Annibal, A.
  • Schiffer, I.
  • Laboy, R.
  • Atanassov, I.
  • Weber, A. L.
  • Gerisch, B.
  • Antebi, A.
(2020) Nat Metab, 2, 5, 387-396

Evolutionarily conserved regulation of immunity by the splicing factor RNP-6/PUF60

  • Kew, C.
  • Huang, W.
  • Fischer, J.
  • Ganesan, R.
  • Robinson, N.
  • Antebi, A.
(2020) Elife, 9

The inherent challenges of classifying senescence-Response

  • Calimport, S. R. G.
  • Bentley, B. L.
  • Stewart, C. E.
  • Pawelec, G.
  • Scuteri, A.
  • Vinciguerra, M.
  • Slack, C.
  • Chen, D.
  • Harries, L. W.
  • Marchant, G.
  • Fleming, G. A.
  • Conboy, M.
  • Antebi, A.
  • Small, G. W.
  • Gil, J.
  • Lakatta, E. G.
  • Richardson, A.
  • Rosen, C.
  • Nikolich, K.
  • Wyss-Coray, T.
  • Steinman, L.
  • Montine, T.
  • de Magalhaes, J. P.
  • Campisi, J.
  • Church, G.
(2020) Science, 368, 6491, 595-596

HLH-30/TFEB Is a Master Regulator of Reproductive Quiescence

  • Gerisch, B.
  • Tharyan, R. G.
  • Mak, J.
  • Denzel, S. I.
  • Popkes-van Oepen, T.
  • Henn, N.
  • Antebi, A.
(2020) Dev Cell, 53, 3, 316-329 e5

Optimization of mass spectrometry settings for steroidomic analysis in young and old killifish

  • Dabrowski, R.
  • Ripa, R.
  • Latza, C.
  • Annibal, A.
  • Antebi, A.
(2020) Anal Bioanal Chem

Hexosamine Pathway Activation Improves Protein Homeostasis through the Integrated Stress Response

  • Horn, M.
  • Denzel, S. I.
  • Srinivasan, B.
  • Allmeroth, K.
  • Schiffer, I.
  • Karthikaisamy, V.
  • Miethe, S.
  • Breuer, P.
  • Antebi, A.
  • Denzel, M. S.
(2020) iScience, 23, 3, 100887

Latest advances in aging research and drug discovery

  • Bakula, D.
  • Ablasser, A.
  • Aguzzi, A.
  • Antebi, A.
  • Barzilai, N.
  • Bittner, M. I.
  • Jensen, M. B.
  • Calkhoven, C. F.
  • Chen, D.
  • Grey, Adnj
  • Feige, J. N.
  • Georgievskaya, A.
  • Gladyshev, V. N.
  • Golato, T.
  • Gudkov, A. V.
  • Hoppe, T.
  • Kaeberlein, M.
  • Katajisto, P.
  • Kennedy, B. K.
  • Lal, U.
  • Martin-Villalba, A.
  • Moskalev, A. A.
  • Ozerov, I.
  • Petr, M. A.
  • Reason,
  • Rubinsztein, D. C.
  • Tyshkovskiy, A.
  • Vanhaelen, Q.
  • Zhavoronkov, A.
  • Scheibye-Knudsen, M.
(2019) Aging (Albany NY), 11, 22, 9971-9981

Cell cycle dynamics during diapause entry and exit in an annual killifish revealed by FUCCI technology

  • Dolfi, L.
  • Ripa, R.
  • Antebi, A.
  • Valenzano, D. R.
  • Cellerino, A.
(2019) Evodevo, 10, 29

Dietary sulfur amino acid restriction upregulates DICER to confer beneficial effects

  • Guerra, B. A.
  • Brandao, B. B.
  • Pinto, S. S.
  • Salgueiro, W. G.
  • De-Souza, E. A.
  • Reis, F. C. G.
  • Batista, T. M.
  • Cavalcante-Silva, V.
  • D'Almeida, V.
  • Castilho, B. A.
  • Carneiro, E. M.
  • Antebi, A.
  • Festuccia, W. T.
  • Mori, M. A.
(2019) Mol Metab, 29, 124-135

To help aging populations, classify organismal senescence

  • Calimport, S. R. G.
  • Bentley, B. L.
  • Stewart, C. E.
  • Pawelec, G.
  • Scuteri, A.
  • Vinciguerra, M.
  • Slack, C.
  • Chen, D.
  • Harries, L. W.
  • Marchant, G.
  • Fleming, G. A.
  • Conboy, M.
  • Antebi, A.
  • Small, G. W.
  • Gil, J.
  • Lakatta, E. G.
  • Richardson, A.
  • Rosen, C.
  • Nikolich, K.
  • Wyss-Coray, T.
  • Steinman, L.
  • Montine, T.
  • de Magalhaes, J. P.
  • Campisi, J.
  • Church, G.
(2019) Science, 366, 6465, 576-578

A secreted microRNA disrupts autophagy in distinct tissues of Caenorhabditis elegans upon ageing

  • Zhou, Y.
  • Wang, X.
  • Song, M.
  • He, Z.
  • Cui, G.
  • Peng, G.
  • Dieterich, C.
  • Antebi, A.
  • Jing, N.
  • Shen, Y.
(2019) Nat Commun, 10, 1, 4827

Pluronic gel-based burrowing assay for rapid assessment of neuromuscular health in C. elegans

  • Lesanpezeshki, L.
  • Hewitt, J. E.
  • Laranjeiro, R.
  • Antebi, A.
  • Driscoll, M.
  • Szewczyk, N. J.
  • Blawzdziewicz, J.
  • Lacerda, C. M. R.
  • Vanapalli, S. A.
(2019) Sci Rep, 9, 1, 15246

Leptin signaling impairs macrophage defenses against Salmonella Typhimurium

  • Fischer, J.
  • Gutierrez, S.
  • Ganesan, R.
  • Calabrese, C.
  • Ranjan, R.
  • Cildir, G.
  • Judith Hos, N.
  • Rybniker, J.
  • Wolke, M.
  • Fries, J. W. U.
  • Tergaonkar, V.
  • Plum, G.
  • Antebi, A.
  • Robinson, N.
(2019) Proc Natl Acad Sci U S A, 116, 33, 16551-16560

Developmental Timing: Honey, I Reprogrammed the Kids

  • Antebi, A.
(2019) Curr Biol, 29, 11, R420-R422

RNA interference may result in unexpected phenotypes in Caenorhabditis elegans

  • De-Souza, E. A.
  • Camara, H.
  • Salgueiro, W. G.
  • Moro, R. P.
  • Knittel, T. L.
  • Tonon, G.
  • Pinto, S.
  • Pinca, A. P. F.
  • Antebi, A.
  • Pasquinelli, A. E.
  • Massirer, K. B.
  • Mori, M. A.
(2019) Nucleic Acids Res, 47, 8, 3957-3969

Comparison of ESI-MS/MS and APCI-MS methods for the quantification of folic acid analogs in C. elegans

  • Annibal, A.
  • Tam, H.
  • Latza, C.
  • Antebi, A.
(2019) J Mass Spectrom, 54, 4, 316-327

Suppression of autophagic activity by Rubicon is a signature of aging

  • Nakamura, S.
  • Oba, M.
  • Suzuki, M.
  • Takahashi, A.
  • Yamamuro, T.
  • Fujiwara, M.
  • Ikenaka, K.
  • Minami, S.
  • Tabata, N.
  • Yamamoto, K.
  • Kubo, S.
  • Tokumura, A.
  • Akamatsu, K.
  • Miyazaki, Y.
  • Kawabata, T.
  • Hamasaki, M.
  • Fukui, K.
  • Sango, K.
  • Watanabe, Y.
  • Takabatake, Y.
  • Kitajima, T. S.
  • Okada, Y.
  • Mochizuki, H.
  • Isaka, Y.
  • Antebi, A.
  • Yoshimori, T.
(2019) Nat Commun, 10, 1, 847

Nucleolar fibrillarin is an evolutionarily conserved regulator of bacterial pathogen resistance

  • Tiku, V.
  • Kew, C.
  • Mehrotra, P.
  • Ganesan, R.
  • Robinson, N.
  • Antebi, A.
(2018) Nat Commun, 9, 1, 3607

A novel EI-GC/MS method for the accurate quantification of anti-aging compound oleoylethanolamine in C. elegans

  • Annibal, A.
  • Karalay, o.
  • Latza, C.
  • Antebi, A.**
(2018) Analytical Methods, 22

Nucleolar Function in Lifespan Regulation

  • Tiku, V.
  • Antebi, A.
(2018) Trends Cell Biol

LIN-28 balances longevity and germline stem cell number in Caenorhabditis elegans through let-7/AKT/DAF-16 axis

  • Wang, D.
  • Hou, L.
  • Nakamura, S.
  • Su, M.
  • Li, F.
  • Chen, W.
  • Yan, Y.
  • Green, C. D.
  • Chen, D.
  • Zhang, H.
  • Antebi, A.
  • Han, J. J.
(2017) Aging Cell, 2017 Feb, 16(1), 113-124

Larval crowding accelerates C. elegans development and reduces lifespan

  • Ludewig, A. H.
  • Gimond, C.
  • Judkins, J. C.
  • Thornton, S.
  • Pulido, D. C.
  • Micikas, R. J.
  • Doring, F.
  • Antebi, A.
  • Braendle, C.
  • Schroeder, F. C.
(2017) PLoS Genet, 13, 4, e1006717

Role of the Max Planck Institute in Ageing Research in Germany

  • Valenzano, D. R.
  • Antebi, A.
(2017) Experimental Medicine (Japan), 35: 76-83

Small nucleoli are a cellular hallmark of longevity

  • Tiku, V.
  • Jain, C.
  • Raz, Y.
  • Nakamura, S.
  • Heestand, B.
  • Liu, W.
  • Spath, M.
  • Suchiman, H. E. D.
  • Muller, R. U.
  • Slagboom, P. E.
  • Partridge, L.
  • Antebi, A.
(2017) Nat Commun, 8, 16083

Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an alpha-glucosidase inhibitor or a Nrf2-inducer

  • Strong, R.
  • Miller, R. A.
  • Antebi, A.
  • Astle, C. M.
  • Bogue, M.
  • Denzel, M. S.
  • Fernandez, E.
  • Flurkey, K.
  • Hamilton, K. L.
  • Lamming, D. W.
  • Javors, M. A.
  • de Magalhaes, J. P.
  • Martinez, P. A.
  • McCord, J. M.
  • Miller, B. F.
  • Muller, M.
  • Nelson, J. F.
  • Ndukum, J.
  • Rainger, G. E.
  • Richardson, A.
  • Sabatini, D. M.
  • Salmon, A. B.
  • Simpkins, J. W.
  • Steegenga, W. T.
  • Nadon, N. L.
  • Harrison, D. E.
(2016) Aging Cell, 15, 5, 872-84

Oral Supplementation of Glucosamine Fails to Alleviate Acute Kidney Injury in Renal Ischemia-Reperfusion Damage

  • Johnsen, M.
  • Spath, M. R.
  • Denzel, M. S.
  • Gobel, H.
  • Kubacki, T.
  • Hoyer, K. J.
  • Hinze, Y.
  • Benzing, T.
  • Schermer, B.
  • Antebi, A.
  • Burst, V.
  • Muller, R. U.
(2016) PLoS One, 11, 8, e0161315

Mondo complexes regulate TFEB via TOR inhibition to promote longevity in response to gonadal signals

  • Nakamura, S.
  • Karalay, O.
  • Jager, P. S.
  • Horikawa, M.
  • Klein, C.
  • Nakamura, K.
  • Latza, C.
  • Templer, S. E.
  • Dieterich, C.
  • Antebi, A.
(2016) Nat Commun, 7, 10944

Mutation of C. elegans demethylase spr-5 extends transgenerational longevity

  • Greer, E. L.
  • Becker, B.
  • Latza, C.
  • Antebi, A.
  • Shi, Y.
(2016) Cell Res, 26, 2, 229-38

Interventions to Slow Aging in Humans: Are We Ready?

  • Longo, V. D.
  • Antebi, A.
  • Bartke, A.
  • Barzilai, N.
  • Brown-Borg, H. M.
  • Caruso, C.
  • Curiel, T. J.
  • de Cabo, R.
  • Franceschi, C.
  • Gems, D.
  • Ingram, D. K.
  • Johnson, T. E.
  • Kennedy, B. K.
  • Kenyon, C.
  • Klein, S.
  • Kopchick, J. J.
  • Lepperdinger, G.
  • Madeo, F.
  • Mirisola, M. G.
  • Mitchell, J. R.
  • Passarino, G.
  • Rudolph, K. L.
  • Sedivy, J. M.
  • Shadel, G. S.
  • Sinclair, D. A.
  • Spindler, S. R.
  • Suh, Y.
  • Vijg, J.
  • Vinciguerra, M.
  • Fontana, L.
(2015) Aging Cell, 14, 4, 497-510

Nuclear receptor signal transduction in C. elegans

  • Antebi, A.
(2015) WormBook, 1-49

Co-chaperone p23 regulates C. elegans Lifespan in Response to Temperature

  • Horikawa, M.
  • Sural, S.
  • Hsu, A. L.
  • Antebi, A.
(2015) PLoS Genet, 11, 4, e1005023

Hexosamine pathway and (ER) protein quality control

  • Denzel, M. S.
  • Antebi, A.
(2015) Curr Opin Cell Biol, 33, 14-8

DRE-1/FBXO11-dependent degradation of BLMP-1/BLIMP-1 governs C. elegans developmental timing and maturation

  • Horn, M.
  • Geisen, C.
  • Cermak, L.
  • Becker, B.
  • Nakamura, S.
  • Klein, C.
  • Pagano, M.
  • Antebi, A.
(2014) Dev Cell, 28, 6, 697-710

Hexosamine pathway metabolites enhance protein quality control and prolong life

  • Denzel, M. S.
  • Storm, N. J.
  • Gutschmidt, A.
  • Baddi, R.
  • Hinze, Y.
  • Jarosch, E.
  • Sommer, T.
  • Hoppe, T.
  • Antebi, A.
(2014) Cell, 156, 6, 1167-78

An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology

  • Fernandes de Abreu, D. A.
  • Caballero, A.
  • Fardel, P.
  • Stroustrup, N.
  • Chen, Z.
  • Lee, K.
  • Keyes, W. D.
  • Nash, Z. M.
  • Lopez-Moyado, I. F.
  • Vaggi, F.
  • Cornils, A.
  • Regenass, M.
  • Neagu, A.
  • Ostojic, I.
  • Liu, C.
  • Cho, Y.
  • Sifoglu, D.
  • Shen, Y.
  • Fontana, W.
  • Lu, H.
  • Csikasz-Nagy, A.
  • Murphy, C. T.
  • Antebi, A.
  • Blanc, E.
  • Apfeld, J.
  • Zhang, Y.
  • Alcedo, J.
  • Ch'ng, Q.
(2014) PLoS Genet, 10, 3, e1004225

A photocleavable masked nuclear-receptor ligand enables temporal control of C. elegans development

  • Judkins, J. C.
  • Mahanti, P.
  • Hoffman, J. B.
  • Yim, I.
  • Antebi, A.
  • Schroeder, F. C.
(2014) Angew Chem Int Ed Engl, 53, 8, 2110-3

Comparative metabolomics reveals endogenous ligands of DAF-12, a nuclear hormone receptor, regulating C. elegans development and lifespan

  • Mahanti, P.
  • Bose, N.
  • Bethke, A.
  • Judkins, J. C.
  • Wollam, J.
  • Dumas, K. J.
  • Zimmerman, A. M.
  • Campbell, S. L.
  • Hu, P. J.
  • Antebi, A.
  • Schroeder, F. C.
(2014) Cell Metab, 19, 1, 73-83

Steroid regulation of C. elegans diapause, developmental timing, and longevity

  • Antebi, A.
(2013) Curr Top Dev Biol, 105, 181-212

The NHR-8 nuclear receptor regulates cholesterol and bile acid homeostasis in C. elegans

  • Magner, D. B.
  • Wollam, J.
  • Shen, Y.
  • Hoppe, C.
  • Li, D.
  • Latza, C.
  • Rottiers, V.
  • Hutter, H.
  • Antebi, A.
(2013) Cell Metab, 18, 2, 212-24

Dietary restriction induced longevity is mediated by nuclear receptor NHR-62 in Caenorhabditis elegans

  • Heestand, B. N.
  • Shen, Y.
  • Liu, W.
  • Magner, D. B.
  • Storm, N.
  • Meharg, C.
  • Habermann, B.
  • Antebi, A.
(2013) PLoS Genet, 9, 7, e1003651

Regulation of longevity by the reproductive system

  • Antebi, A.
(2013) Exp Gerontol, 48, 7, 596-602

Regulation of the CRL4(Cdt2) ubiquitin ligase and cell-cycle exit by the SCF(Fbxo11) ubiquitin ligase

  • Rossi, M.
  • Duan, S.
  • Jeong, Y. T.
  • Horn, M.
  • Saraf, A.
  • Florens, L.
  • Washburn, M. P.
  • Antebi, A.
  • Pagano, M.
(2013) Mol Cell, 49, 6, 1159-66

Aging Cell in 2012. Editorial

  • Adams, P.
  • Antebi, A.
  • Cuervo, A. M.
  • Kennedy, B.
  • Sedivy, J.
(2013) Aging Cell, 12, 1, 1

A steroid receptor-microRNA switch regulates life span in response to signals from the gonad

  • Shen, Y.
  • Wollam, J.
  • Magner, D.
  • Karalay, O.
  • Antebi, A.
(2012) Science, 338, 6113, 1472-6

Hormonal signal amplification mediates environmental conditions during development and controls an irreversible commitment to adulthood

  • Schaedel, O. N.
  • Gerisch, B.
  • Antebi, A.
  • Sternberg, P. W.
(2012) PLoS Biol, 10, 4, e1001306

A novel 3-hydroxysteroid dehydrogenase that regulates reproductive development and longevity

  • Wollam, J.
  • Magner, D. B.
  • Magomedova, L.
  • Rass, E.
  • Shen, Y.
  • Rottiers, V.
  • Habermann, B.
  • Cummins, C. L.
  • Antebi, A.
(2012) PLoS Biol, 10, 4, e1001305

Regulation of neuronal APL-1 expression by cholesterol starvation

  • Wiese, M.
  • Antebi, A.
  • Zheng, H.
(2012) PLoS One, 7, 2, e32038

The Rieske oxygenase DAF-36 functions as a cholesterol 7-desaturase in steroidogenic pathways governing longevity

  • Wollam, J.
  • Magomedova, L.
  • Magner, D. B.
  • Shen, Y.
  • Rottiers, V.
  • Motola, D. L.
  • Mangelsdorf, D. J.
  • Cummins, C. L.
  • Antebi, A.
(2011) Aging Cell, 10, 5, 879-84

Sterol regulation of metabolism, homeostasis, and development

  • Wollam, J.
  • Antebi, A.
(2011) Annu Rev Biochem, 80, 885-916

Molecular basis of life history regulation in C. Elegans and other organisms

  • Gerisch, B.
  • Antebi, A.
(2011) Mechanisms of Life History Evolution

Intracellular trafficking and synaptic function of APL-1 in Caenorhabditis elegans

  • Wiese, M.
  • Antebi, A.
  • Zheng, H.
(2010) PLoS One, 5, 9

Nuclear hormone receptor regulation of microRNAs controls developmental progression

  • Bethke, A.
  • Fielenbach, N.
  • Wang, Z.
  • Mangelsdorf, D. J.
  • Antebi, A.
(2009) Science, 324, 5923, 95-8

Mitochondrial DNA level, but not active replicase, is essential for Caenorhabditis elegans development

  • Bratic, I.
  • Hench, J.
  • Henriksson, J.
  • Antebi, A.
  • Burglin, T. R.
  • Trifunovic, A.
(2009) Nucleic Acids Res, 37, 6, 1817-28

Announcements from your Editorial Team

  • Antebi, A.
  • Cuervo, A. M.
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