Publikationen Gruppe Denzel

Bortezomib resistance mutations in PSMB5 determine response to second-generation proteasome inhibitors in multiple myeloma

  • Allmeroth, K.
  • Horn, M.
  • Kroef, V.
  • Miethe, S.
  • Muller, R. U.
  • Denzel, M. S.
(2020) Leukemia

Hexosamine Pathway Activation Improves Protein Homeostasis through the Integrated Stress Response

  • Horn, M.
  • Denzel, S. I.
  • Srinivasan, B.
  • Allmeroth, K.
  • Schiffer, I.
  • Karthikaisamy, V.
  • Miethe, S.
  • Breuer, P.
  • Antebi, A.
  • Denzel, M. S.
(2020) iScience, 23, 3, 100887

Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis

  • Ruegenberg, S.
  • Horn, M.
  • Pichlo, C.
  • Allmeroth, K.
  • Baumann, U.
  • Denzel, M. S.
(2020) Nat Commun, 11, 1, 687

The E3 ubiquitin ligase UBR5 interacts with the H/ACA ribonucleoprotein complex and regulates ribosomal RNA biogenesis in embryonic stem cells

  • Saez, I.
  • Gerbracht, J. V.
  • Koyuncu, S.
  • Lee, H. J.
  • Horn, M.
  • Kroef, V.
  • Denzel, M. S.
  • Dieterich, C.
  • Gehring, N. H.
  • Vilchez, D.
(2020) FEBS Lett, 594, 1, 175-188

Unbiased Forward Genetic Screening with Chemical Mutagenesis to Uncover Drug-Target Interactions

  • Horn, M.
  • Metge, F.
  • Denzel, M. S.
(2019) Methods Mol Biol, 1953, 23-31

Chaperoning junior faculty: Institutional support and guidance can relieve challenges for early-career group leaders and improve academic performance

  • Sawarkar, R.
  • Scherz-Shouval, R.
  • Denzel, M. S.
  • Saarikangas, J.
(2019) EMBO Rep, 20, 1

Emerging topics in C. elegans aging research: Transcriptional regulation, stress response and epigenetics

  • Denzel, M. S.
  • Lapierre, L. R.
  • Mack, H. I. D.
(2019) Mech Ageing Dev, 177, 4-21

Preparing junior faculty for success

  • Sawarkar, R.
  • Scherz-Shouval, R.
  • Denzel, M.
  • Saarikangas, J.
(2018) Science, 361, 6399, 238

Improved protein-crystal identification by using 2,2,2-trichloroethanol as a fluorescence enhancer

  • Pichlo, C.
  • Toelzer, C.
  • Chojnacki, K.
  • Ocal, S.
  • Uthoff, M.
  • Ruegenberg, S.
  • Hermanns, T.
  • Schacherl, M.
  • Denzel, M. S.
  • Hofmann, K.
  • Niefind, K.
  • Baumann, U.
(2018) Acta Crystallogr F Struct Biol Commun, 74, Pt 5, 307-314

Unbiased compound-protein interface mapping and prediction of chemoresistance loci through forward genetics in haploid stem cells

  • Horn, M.
  • Kroef, V.
  • Allmeroth, K.
  • Schuller, N.
  • Miethe, S.
  • Peifer, M.
  • Penninger, J. M.
  • Elling, U.
  • Denzel, M. S.
(2018) Oncotarget, 9, 11, 9838-9851

Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an alpha-glucosidase inhibitor or a Nrf2-inducer

  • Strong, R.
  • Miller, R. A.
  • Antebi, A.
  • Astle, C. M.
  • Bogue, M.
  • Denzel, M. S.
  • Fernandez, E.
  • Flurkey, K.
  • Hamilton, K. L.
  • Lamming, D. W.
  • Javors, M. A.
  • de Magalhaes, J. P.
  • Martinez, P. A.
  • McCord, J. M.
  • Miller, B. F.
  • Muller, M.
  • Nelson, J. F.
  • Ndukum, J.
  • Rainger, G. E.
  • Richardson, A.
  • Sabatini, D. M.
  • Salmon, A. B.
  • Simpkins, J. W.
  • Steegenga, W. T.
  • Nadon, N. L.
  • Harrison, D. E.
(2016) Aging Cell, 15, 5, 872-84

Oral Supplementation of Glucosamine Fails to Alleviate Acute Kidney Injury in Renal Ischemia-Reperfusion Damage

  • Johnsen, M.
  • Spath, M. R.
  • Denzel, M. S.
  • Gobel, H.
  • Kubacki, T.
  • Hoyer, K. J.
  • Hinze, Y.
  • Benzing, T.
  • Schermer, B.
  • Antebi, A.
  • Burst, V.
  • Muller, R. U.
(2016) PLoS One, 11, 8, e0161315

hESC Differentiation toward an Autonomic Neuronal Cell Fate Depends on Distinct Cues from the Co-Patterning Vasculature

  • Acevedo, L. M.
  • Lindquist, J. N.
  • Walsh, B. M.
  • Sia, P.
  • Cimadamore, F.
  • Chen, C.
  • Denzel, M.
  • Pernia, C. D.
  • Ranscht, B.
  • Terskikh, A.
  • Snyder, E. Y.
  • Cheresh, D. A.
(2015) Stem Cell Reports, 4, 6, 1075-88

Hexosamine pathway and (ER) protein quality control

  • Denzel, M. S.
  • Antebi, A.
(2015) Curr Opin Cell Biol, 33, 14-8

Hexosamine pathway metabolites enhance protein quality control and prolong life

  • Denzel, M. S.*
  • Storm, N. J.*
  • Gutschmidt, A.
  • Baddi, R.
  • Hinze, Y.
  • Jarosch, E.
  • Sommer, T.
  • Hoppe, T.
  • Antebi, A.
(2014) Cell, 156, 6, 1167-78

T-cadherin is essential for adiponectin-mediated revascularization

  • Parker-Duffen, J. L.
  • Nakamura, K.
  • Silver, M.
  • Kikuchi, R.
  • Tigges, U.
  • Yoshida, S.
  • Denzel, M. S.
  • Ranscht, B.
  • Walsh, K.
(2013) J Biol Chem, 288, 34, 24886-97

Multivalent proteoglycan modulation of FGF mitogenic responses in perivascular cells

  • Cattaruzza, S.
  • Ozerdem, U.
  • Denzel, M.
  • Ranscht, B.
  • Bulian, P.
  • Cavallaro, U.
  • Zanocco, D.
  • Colombatti, A.
  • Stallcup, W. B.
  • Perris, R.
(2013) Angiogenesis, 16, 2, 309-27

Adiponectin attenuates lipopolysaccharide-induced acute lung injury through suppression of endothelial cell activation

  • Konter, J. M.
  • Parker, J. L.
  • Baez, E.
  • Li, S. Z.
  • Ranscht, B.
  • Denzel, M.
  • Little, F. F.
  • Nakamura, K.
  • Ouchi, N.
  • Fine, A.
  • Walsh, K.
  • Summer, R. S.
(2012) J Immunol, 188, 2, 854-63

T-cadherin (Cdh13) in association with pancreatic beta-cell granules contributes to second phase insulin secretion

  • Tyrberg, B.
  • Miles, P.
  • Azizian, K. T.
  • Denzel, M. S.
  • Nieves, M. L.
  • Monosov, E. Z.
  • Levine, F.
  • Ranscht, B.
(2011) Islets, 3, 6, 327-37

T-cadherin is critical for adiponectin-mediated cardioprotection in mice

  • Denzel, M. S.
  • Scimia, M. C.
  • Zumstein, P. M.
  • Walsh, K.
  • Ruiz-Lozano, P.
  • Ranscht, B.
(2010) J Clin Invest, 120, 12, 4342-52

Adiponectin deficiency limits tumor vascularization in the MMTV-PyV-mT mouse model of mammary cancer

  • Denzel, M. S.
  • Hebbard, L. W.
  • Shostak, G.
  • Shapiro, L.
  • Cardiff, R. D.
  • Ranscht, B.
(2009) Clin Cancer Res, 15, 10, 3256-64

The heme synthesis defect of mutants impaired in mitochondrial iron-sulfur protein biogenesis is caused by reversible inhibition of ferrochelatase

  • Lange, H.
  • Muhlenhoff, U.
  • Denzel, M.
  • Kispal, G.
  • Lill, R.
(2004) J Biol Chem, 279, 28, 29101-8

*gleichwertiger Beitrag; **korrespondierender Autor