Max-Planck-Forschungsgruppe Jachimowicz

Publikationen

Correspondence to: hemophagocytic lymphohistiocytosis after SARS-CoV-2 vaccination

  • Sprute, R.
  • Hieber, M. L.
  • Jachimowicz, R. D.
(2022) Infection, 50, 6, 1617-1618

Distinct genetically-determined origins of Myd88/Bcl2-driven aggressive lymphoma rationalize targeted therapeutic intervention strategies

  • Flumann, R.
  • Hansen, J.
  • Pelzer, B. W.
  • Nieper, P.
  • Lohmann, T.
  • Kisis, I.
  • Riet, T.
  • Kohlhas, V.
  • Nguyen, P. H.
  • Peifer, M.
  • Abedpour, N.
  • Bosco, G.
  • Thomas, R. K.
  • Kochanek, M.
  • Knufer, J.
  • Jonigkeit, L.
  • Beleggia, F.
  • Holzem, A.
  • Buttner, R.
  • Lohneis, P.
  • Meinel, J.
  • Ortmann, M.
  • Persigehl, T.
  • Hallek, M.
  • Calado, D. P.
  • Chmielewski, M.
  • Klein, S.
  • Gothert, J. R.
  • Chapuy, B.
  • Zevnik, B.
  • Wunderlich, F. T.
  • von Tresckow, B.
  • Jachimowicz, R. D.
  • Melnick, A. M.
  • Reinhardt, H. C.
  • Knittel, G.
(2022) Blood Cancer Discov

Genomic Amplification of UBQLN4 Is a Prognostic and Treatment Resistance Factor

  • Kobayashi, Y.
  • Bustos, M. A.
  • Shoji, Y.
  • Jachimowicz, R. D.
  • Shiloh, Y.
  • Hoon, D. S. B.
(2022) Cells, 11, 20

Hemophagocytic lymphohistiocytosis after SARS-CoV-2 vaccination

  • Hieber, M. L.
  • Sprute, R.
  • Eichenauer, D. A.
  • Hallek, M.
  • Jachimowicz, R. D.
(2022) Infection, 50, 5, 1399-1404

Combined inhibition of EZH2 and ATM is synthetic lethal in BRCA1-deficient breast cancer

  • Ratz, L.
  • Brambillasca, C.
  • Bartke, L.
  • Huetzen, M. A.
  • Goergens, J.
  • Leidecker, O.
  • Jachimowicz, R. D.
  • van de Ven, M.
  • Proost, N.
  • Siteur, B.
  • de Korte-Grimmerink, R.
  • Bouwman, P.
  • Pulver, E. M.
  • de Bruijn, R.
  • Isensee, J.
  • Hucho, T.
  • Pandey, G.
  • van Lohuizen, M.
  • Mallmann, P.
  • Reinhardt, H. C.
  • Jonkers, J.
  • Puppe, J.
(2022) Breast Cancer Res, 24, 1, 41

Correspondence to: hemophagocytic lymphohistiocytosis after SARS-CoV-2 vaccination

  • Sprute, R.
  • Hieber, M. L.
  • Jachimowicz, R. D.
(2022) Infection

Hemophagocytic lymphohistiocytosis after SARS-CoV-2 vaccination

  • Hieber, M. L.
  • Sprute, R.
  • Eichenauer, D. A.
  • Hallek, M.
  • Jachimowicz, R. D.
(2022) Infection, 1-6

Biallelic variants in YRDC cause a developmental disorder with progeroid features

  • Schmidt, J.
  • Goergens, J.
  • Pochechueva, T.
  • Kotter, A.
  • Schwenzer, N.
  • Sitte, M.
  • Werner, G.
  • Altmüller, J.
  • Thiele, H.
  • Nürnberg, P.
  • Isensee, J.
  • Li, Y.
  • Müller, C.
  • Leube, B.
  • Reinhardt, H. C.
  • Hucho, T.
  • Salinas, G.
  • Helm, M.
  • Jachimowicz, R. D.
  • Wieczorek, D.
  • Kohl, T.
  • Lehnart, S. E.
  • Yigit, G.
  • Wollnik, B.
(2021) Human Genetics, 12, 140, 1679-1693

Gene expression-based outcome prediction in advanced stage classical Hodgkin lymphoma treated with BEACOPP

  • Jachimowicz, R. D.
  • Klapper, W.
  • Glehr, G.
  • Muller, H.
  • Haverkamp, H.
  • Thorns, C.
  • Hansmann, M. L.
  • Moller, P.
  • Stein, H.
  • Rehberg, T.
  • von Tresckow, B.
  • Reinhardt, H. C.
  • Borchmann, P.
  • Chan, F. C.
  • Spang, R.
  • Scott, D. W.
  • Engert, A.
  • Steidl, C.
  • Altenbuchinger, M.
  • Rosenwald, A.
(2021) Leukemia, 35, 12, 3589-3593

Regulation of MRE11A by UBQLN4 leads to cisplatin resistance in patients with esophageal squamous cell carcinoma

  • Murakami, T.
  • Shoji, Y.
  • Nishi, T.
  • Chang, S. C.
  • Jachimowicz, R. D.
  • Hoshimoto, S.
  • Ono, S.
  • Shiloh, Y.
  • Takeuchi, H.
  • Kitagawa, Y.
  • Hoon, D. S. B.
  • Bustos, M. A.
(2021) Mol Oncol, 15, 4, 1069-1087

Targeting DNA Repair, Cell Cycle, and Tumor Microenvironment in B Cell Lymphoma

  • Brockelmann, P. J.
  • de Jong, M. R. W.
  • Jachimowicz, R. D.
(2020) Cells, 9, 10, 2287

Analysis of the tumor microenvironment by whole-slide image analysis identifies low B cell content as a predictor of adverse outcome in advanced-stage classical Hodgkin lymphoma treated with BEACOPP

  • Jachimowicz, R. D.
  • Pieper, L.
  • Reinke, S.
  • Gontarewicz, A.
  • Plutschow, A.
  • Haverkamp, H.
  • Frauenfeld, L.
  • Fend, F.
  • Overkamp, M.
  • Jochims, F.
  • Thorns, C.
  • Hansmann, M. L.
  • Moller, P.
  • Rosenwald, A.
  • Stein, H.
  • Reinhardt, H. C.
  • Borchmann, P.
  • von Tresckow, B.
  • Engert, A.
  • Klapper, W.
(2020) Haematologica, 106, 6, 1684-1692

ATM activity in T cells is critical for immune surveillance of lymphoma in vivo

  • Riabinska, A.
  • Lehrmann, D.
  • Jachimowicz, R. D.
  • Knittel, G.
  • Fritz, C.
  • Schmitt, A.
  • Geyer, A.
  • Heneweer, C.
  • Wittersheim, M.
  • Frenzel, L. P.
  • Torgovnick, A.
  • Wiederstein, J. L.
  • Wunderlich, C. M.
  • Ortmann, M.
  • Paillard, A.
  • Wossmann, W.
  • Borkhardt, A.
  • Burdach, S.
  • Hansmann, M. L.
  • Rosenwald, A.
  • Perner, S.
  • Mall, G.
  • Klapper, W.
  • Merseburg, A.
  • Kruger, M.
  • Grull, H.
  • Persigehl, T.
  • Wunderlich, F. T.
  • Peifer, M.
  • Utermohlen, O.
  • Buttner, R.
  • Beleggia, F.
  • Reinhardt, H. C.
(2020) Leukemia, 34, 3, 771-786

MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer

  • Dammert, M. A.
  • Bragelmann, J.
  • Olsen, R. R.
  • Bohm, S.
  • Monhasery, N.
  • Whitney, C. P.
  • Chalishazar, M. D.
  • Tumbrink, H. L.
  • Guthrie, M. R.
  • Klein, S.
  • Ireland, A. S.
  • Ryan, J.
  • Schmitt, A.
  • Marx, A.
  • Ozretic, L.
  • Castiglione, R.
  • Lorenz, C.
  • Jachimowicz, R. D.
  • Wolf, E.
  • Thomas, R. K.
  • Poirier, J. T.
  • Buttner, R.
  • Sen, T.
  • Byers, L. A.
  • Reinhardt, H. C.
  • Letai, A.
  • Oliver, T. G.
  • Sos, M. L.
(2019) Nat Commun, 10, 1, 3485

DNA double-strand break repair pathway choice - from basic biology to clinical exploitation

  • Jachimowicz, R. D.
  • Goergens, J.
  • Reinhardt, H. C.
(2019) Cell Cycle, 18, 13, 1423-1434

UBQLN4 promotes non-homologous end joining by repressing DNA end-resection

  • Jachimowicz, R. D.
  • Reinhardt, H. C.
(2019) Mol Cell Oncol, 6, 2, 1575692

UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors

  • Jachimowicz, R. D.
  • Beleggia, F.
  • Isensee, J.
  • Velpula, B. B.
  • Goergens, J.
  • Bustos, M. A.
  • Doll, M. A.
  • Shenoy, A.
  • Checa-Rodriguez, C.
  • Wiederstein, J. L.
  • Baranes-Bachar, K.
  • Bartenhagen, C.
  • Hertwig, F.
  • Teper, N.
  • Nishi, T.
  • Schmitt, A.
  • Distelmaier, F.
  • Ludecke, H. J.
  • Albrecht, B.
  • Kruger, M.
  • Schumacher, B.
  • Geiger, T.
  • Hoon, D. S. B.
  • Huertas, P.
  • Fischer, M.
  • Hucho, T.
  • Peifer, M.
  • Ziv, Y.
  • Reinhardt, H. C.
  • Wieczorek, D.
  • Shiloh, Y.
(2019) Cell, 176, 3, 505-519 e22

Clonal dynamics towards the development of venetoclax resistance in chronic lymphocytic leukemia

  • Herling, C. D.
  • Abedpour, N.
  • Weiss, J.
  • Schmitt, A.
  • Jachimowicz, R. D.
  • Merkel, O.
  • Cartolano, M.
  • Oberbeck, S.
  • Mayer, P.
  • Berg, V.
  • Thomalla, D.
  • Kutsch, N.
  • Stiefelhagen, M.
  • Cramer, P.
  • Wendtner, C. M.
  • Persigehl, T.
  • Saleh, A.
  • Altmuller, J.
  • Nurnberg, P.
  • Pallasch, C.
  • Achter, V.
  • Lang, U.
  • Eichhorst, B.
  • Castiglione, R.
  • Schafer, S. C.
  • Buttner, R.
  • Kreuzer, K. A.
  • Reinhardt, H. C.
  • Hallek, M.
  • Frenzel, L. P.
  • Peifer, M.
(2018) Nat Commun, 9, 1, 727

Multi-specific antibodies for cancer immunotherapy

  • Jachimowicz, R. D.
  • Borchmann, S.
  • Rothe, A.
(2014) BioDrugs, 28, 4, 331-43

The bispecific immunoligand ULBP2-aCEA redirects natural killer cells to tumor cells and reveals potent anti-tumor activity against colon carcinoma

  • Rothe, A.
  • Jachimowicz, R. D.
  • Borchmann, S.
  • Madlener, M.
  • Kessler, J.
  • Reiners, K. S.
  • Sauer, M.
  • Hansen, H. P.
  • Ullrich, R. T.
  • Chatterjee, S.
  • Borchmann, P.
  • Yazaki, P.
  • Koslowsky, T. C.
  • Engert, A.
  • Heukamp, L. C.
  • Hallek, M.
  • von Strandmann, E. P.
(2014) Int J Cancer, 134, 12, 2829-40

A functional cancer genomics screen identifies a druggable synthetic lethal interaction between MSH3 and PRKDC

  • Dietlein, F.
  • Thelen, L.
  • Jokic, M.
  • Jachimowicz, R. D.
  • Ivan, L.
  • Knittel, G.
  • Leeser, U.
  • van Oers, J.
  • Edelmann, W.
  • Heukamp, L. C.
  • Reinhardt, H. C.
(2014) Cancer Discov, 4, 5, 592-605

The challenging aspects of managing adolescents and young adults with Hodgkin's lymphoma

  • Jachimowicz, R. D.
  • Engert, A.
(2014) Acta Haematol, 132, 3-4, 274-8

Baseline serum TARC levels predict therapy outcome in patients with Hodgkin lymphoma

  • Sauer, M.
  • Plutschow, A.
  • Jachimowicz, R. D.
  • Kleefisch, D.
  • Reiners, K. S.
  • Ponader, S.
  • Engert, A.
  • von Strandmann, E. P.
(2013) Am J Hematol, 88, 2, 113-5

Induction of in vitro and in vivo NK cell cytotoxicity using high-avidity immunoligands targeting prostate-specific membrane antigen in prostate carcinoma

  • Jachimowicz, R. D.
  • Fracasso, G.
  • Yazaki, P. J.
  • Power, B. E.
  • Borchmann, P.
  • Engert, A.
  • Hansen, H. P.
  • Reiners, K. S.
  • Marie, M.
  • von Strandmann, E. P.
  • Rothe, A.
(2011) Mol Cancer Ther, 10, 6, 1036-45

*equal contribution **corresponding author