Max-Planck-Forschungsgruppe Tessarz

Publikationen

Identifying and visualising multimorbidity and comorbidity patterns in patients in the English National Health Service: a population-based study

  • Kuan, V.
  • Denaxas, S.
  • Patalay, P.
  • Nitsch, D.
  • Mathur, R.
  • Gonzalez-Izquierdo, A.
  • Sofat, R.
  • Partridge, L.
  • Roberts, A.
  • Wong, I. C. K.
  • Hingorani, M.
  • Chaturvedi, N.
  • Hemingway, H.
  • Hingorani, A. D.
  • Multimorbidity, Mechanism
  • Therapeutic Research, Collaborative
(2022) Lancet Digit Health

Effects of Hst3p inhibition in <i>Candida albicans</i>: a genome-wide H3K56 acetylation analysis

  • Conte, M.
  • Eletto, D.
  • Pannetta, M.
  • Petrone, A. M.
  • Monti, M. C.
  • Cassiano, C.
  • Giurato, G.
  • Rizzo, F.
  • Tessarz, P.
  • Petrella, A.
  • Tosco, A.
  • Porta, A.
(2022) Front Cell Infect Microbiol, 12, 1031814

Hypoxia promotes osteogenesis by facilitating acetyl-CoA-mediated mitochondrial-nuclear communication

  • Pouikli, A.
  • Maleszewska, M.
  • Parekh, S.
  • Yang, M.
  • Nikopoulou, C.
  • Bonfiglio, J. J.
  • Mylonas, C.
  • Sandoval, T.
  • Schumacher, A. L.
  • Hinze, Y.
  • Matic, I.
  • Frezza, C.
  • Tessarz, P.
(2022) EMBO J, e111239

Aging is associated with increased chromatin accessibility and reduced polymerase pausing in liver

  • Bozukova, M.
  • Nikopoulou, C.
  • Kleinenkuhnen, N.
  • Grbavac, D.
  • Goetsch, K.
  • Tessarz, P.
(2022) Mol Syst Biol, 18, 9, e11002

RNA-sequencing of single cholangiocyte-derived organoids reveals high organoid-to organoid variability

  • Gehling, K.
  • Parekh, S.
  • Schneider, F.
  • Kirchner, M.
  • Kondylis, V.
  • Nikopoulou, C.
  • Tessarz, P.
(2022) Life Sci Alliance, 5, 12

The impact of genomic variation on protein phosphorylation states and regulatory networks

  • Grossbach, J.
  • Gillet, L.
  • Clement-Ziza, M.
  • Schmalohr, C. L.
  • Schubert, O. T.
  • Schutter, M.
  • Mawer, J. S. P.
  • Barnes, C. A.
  • Bludau, I.
  • Weith, M.
  • Tessarz, P.
  • Graef, M.
  • Aebersold, R.
  • Beyer, A.
(2022) Mol Syst Biol, 18, 5, e10712

Reduced polymerase pausing compensates for increased chromatin accessibility in the aging liver

  • Bozukova, M.
  • Grbavac, D.
  • Nikopoulou, C.
  • Tessarz, P.
(2022) bioRxiv, 2022.02.25.481984

Single-cell resolution unravels spatial alterations in metabolism, transcriptome and epigenome of ageing liver

  • Nikopoulou, C.
  • Kleinenkuhnen, N.
  • Parekh, S.i.
  • Sandoval, T.
  • Schneider, F.
  • Giavalisco, P.
  • Bozukova, M.
  • Vesting, A. J.
  • Altmüller, J.
  • Wunderlich, T.
  • Kondylis, V.
  • Tresch, A.
  • Tessarz, P.
(2021) bioRxiv, 15, 134, jcs259051

Single organoid RNA-sequencing reveals high organoid-to-organoid variability

  • Gehling, K.; Parekh, S.; Schneider, F.; Kirchner, M.; Kondylis, V.; Nikopoulou, C.; Tessarz, P.
(2021) bioRxiv, 2021.11.22.469588

Histone N-terminal acetyltransferase NAA40 links one-carbon metabolism to chemoresistance

  • Demetriadou, C.
  • Raoukka, A.
  • Charidemou, E.
  • Mylonas, C.
  • Michael, C.
  • Parekh, S.
  • Koufaris, C.
  • Skourides, P.
  • Papageorgis, P.
  • Tessarz, P.
  • Kirmizis, A.
(2021) Oncogene, 41, 4, 571-585

Chromatin remodeling due to degradation of citrate carrier impairs osteogenesis of aged mesenchymal stem cells

  • Pouikli, A.
  • Parekh, S.
  • Maleszewska, M.
  • Nikopoulou, C.
  • Baghdadi, M.
  • Tripodi, I.
  • Folz-Donahue, K.
  • Hinze, Y.
  • Mesaros, A.
  • Hoey, D.
  • Giavalisco, P.
  • Dowell, R.
  • Partridge, L.
  • Tessarz, P.
(2021) Nature Aging, 1, 9, 810-825

Nhp2 is a reader of H2AQ105me and part of a network integrating metabolism with rRNA synthesis

  • Mawer, J. S. P.
  • Massen, J.
  • Reichert, C.
  • Grabenhorst, N.
  • Mylonas, C.
  • Tessarz, P.
(2021) EMBO Rep, 10, 22, e52435

The RNA-binding protein Puf5 contributes to buffering of mRNA upon chromatin-mediated changes in nascent transcription

  • Kochan, D. Z.
  • Mawer, J. S. P.
  • Massen, J.
  • Tishinov, K.
  • Parekh, S.
  • Graef, M.
  • Spang, A.
  • Tessarz, P.
(2021) J Cell Sci, 15, 134, jcs259051

Contralateral lymph node metastases in patients with vulvar cancer and unilateral sentinel lymph node metastases

  • Ignatov, T.
  • Gaßner, J.
  • Bozukova, M.
  • Ivros, S.
  • Mészáros, J.
  • Ortmann, O.
  • Eggemann, H.
  • Ignatov, A.
(2021) Acta Obstet Gynecol Scand, 100(8): 1520-1525

Long-lived macrophage reprogramming drives spike protein-mediated inflammasome activation in COVID-19

  • Theobald, S. J.
  • Simonis, A.
  • Georgomanolis, T.
  • Kreer, C.
  • Zehner, M.
  • Eisfeld, H. S.
  • Albert, M. C.
  • Chhen, J.
  • Motameny, S.
  • Erger, F.
  • Fischer, J.
  • Malin, J. J.
  • Gräb, J.
  • Winter, S.
  • Pouikli, A.
  • David, F.
  • Böll, B.
  • Koehler, P.
  • Vanshylla, K.
  • Gruell, H.
  • Suárez, I.
  • Hallek, M.
  • Fätkenheuer, G.
  • Jung, N.
  • Cornely, O. A.
  • Lehmann, C.
  • Tessarz, P.
  • Altmüller, J.
  • Nürnberg, P.
  • Kashkar, H.
  • Klein, F.
  • Koch, M.
  • Rybniker, J.
(2021) EMBO Mol Med, 8, 13, e14150

N1-acetylspermidine is a determinant of hair follicle stem cell fate

  • Allmeroth, K.
  • Kim, C. S.
  • Annibal, A.
  • Pouikli, A.
  • Koester, J.
  • Derisbourg, M. J.
  • Andres Chacon-Martinez, C.
  • Latza, C.
  • Antebi, A.
  • Tessarz, P.
  • Wickstrom, S. A.
  • Denzel, M. S.
(2021) J Cell Sci, 9, 134, jcs252767

Untargeted In Silico Compound Classification-A Novel Metabolomics Method to Assess the Chemodiversity in Bryophytes

  • Peters, K.
  • Balcke, G.
  • Kleinenkuhnen, N.
  • Treutler, H.
  • Neumann, S.
(2021) Int J Mol Sci, 22(6)

Epigenetic alterations in stem cell ageing-a promising target for age-reversing interventions?

  • Pouikli, A.
  • Tessarz, P.
(2021) Brief Funct Genomics, 1, 21, 35-42

Metabolism and chromatin: A dynamic duo that regulates development and ageing: Elucidating the metabolism-chromatin axis in bone-marrow mesenchymal stem cell fate decisions

  • Pouikli, A.
  • Tessarz, P.
(2021) Bioessays, 5, 43, e2000273

Systematic lymphadenectomy in early stage endometrial cancer

  • Ignatov, A.
  • Ivros, S.
  • Bozukova, M.
  • Papathemelis, T.
  • Ortmann, O.
  • Eggemann, H.
(2020) Arch Gynecol Obstet, 302(1): 231-239

Benchmarking single-cell RNA-sequencing protocols for cell atlas projects

  • Mereu, E.
  • Lafzi, A.
  • Moutinho, C.
  • Ziegenhain, C.
  • McCarthy, D. J.
  • Álvarez-Varela, A.
  • Batlle, E.
  • Sagar,
  • Grün, D.
  • Lau, J. K.
  • Boutet, S. C.
  • Sanada, C.
  • Ooi, A.
  • Jones, R. C.
  • Kaihara, K.
  • Brampton, C.
  • Talaga, Y.
  • Sasagawa, Y.
  • Tanaka, K.
  • Hayashi, T.
  • Braeuning, C.
  • Fischer, C.
  • Sauer, S.
  • Trefzer, T.
  • Conrad, C.
  • Adiconis, X.
  • Nguyen, L. T.
  • Regev, A.
  • Levin, J. Z.
  • Parekh, S.
  • Janjic, A.
  • Wange, L. E.
  • Bagnoli, J. W.
  • Enard, W.
  • Gut, M.
  • Sandberg, R.
  • Nikaido, I.
  • Gut, I.
  • Stegle, O.
  • Heyn, H.
(2020) Nat Biotechnol, 38, 6, 747-755

A systematic evaluation of single cell RNA-seq analysis pipelines

  • Vieth, B.
  • Parekh, S.
  • Ziegenhain, C.
  • Enard, W.
  • Hellmann, I.
(2019) Nat Commun, 10, 1, 4667

NET-prism enables RNA polymerase-dedicated transcriptional interrogation at nucleotide resolution

  • Mylonas, C.
  • Tessarz, P.
(2019) RNA Biol, 16, 9, 1156-1165

Ageing and sources of transcriptional heterogeneity

  • Nikopoulou, C.
  • Parekh, S.
  • Tessarz, P.
(2019) Biol Chem, 400, 7, 867-878

SIRT7-Dependent Deacetylation of Fibrillarin Controls Histone H2A Methylation and rRNA Synthesis during the Cell Cycle

  • Iyer-Bierhoff, A.
  • Krogh, N.
  • Tessarz, P.
  • Ruppert, T.
  • Nielsen, H.
  • Grummt, I.
(2018) Cell Rep, 25, 11, 2946-2954 e5

Transcriptional repression by FACT is linked to regulation of chromatin accessibility at the promoter of ES cells

  • Mylonas, C.
  • Tessarz, P.
(2018) Life Sci Alliance, 1, 3, e201800085

Histone Modifications in Ageing and Lifespan Regulation

  • Maleszewska, M.; Mawer, J.S P; Tessarz, P
(2016) Current Molecular Biology Reports, 2(1): 26-35

Histone core modifications regulating nucleosome structure and dynamics

  • Tessarz, P.
  • Kouzarides, T.
(2014) Nat Rev Mol Cell Biol, 15, 11, 703-8

Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modification

  • Tessarz, P.
  • Santos-Rosa, H.
  • Robson, S. C.
  • Sylvestersen, K. B.
  • Nelson, C. J.
  • Nielsen, M. L.
  • Kouzarides, T.
(2014) Nature, 505, 7484, 564-8

Cooperative and independent activities of Sgt2 and Get5 in the targeting of tail-anchored proteins

  • Kohl, C.
  • Tessarz, P.
  • von der Malsburg, K.
  • Zahn, R.
  • Bukau, B.
  • Mogk, A.
(2011) Biol Chem, 392, 7, 601-8

The yeast AAA+ chaperone Hsp104 is part of a network that links the actin cytoskeleton with the inheritance of damaged proteins

  • Tessarz, P.
  • Schwarz, M.
  • Mogk, A.
  • Bukau, B.
(2009) Mol Cell Biol, 29, 13, 3738-45

Substrate threading through the central pore of the Hsp104 chaperone as a common mechanism for protein disaggregation and prion propagation

  • Tessarz, P.
  • Mogk, A.
  • Bukau, B.
(2008) Mol Microbiol, 68, 1, 87-97

Common and specific mechanisms of AAA+ proteins involved in protein quality control

  • Mogk, A.
  • Haslberger, T.
  • Tessarz, P.
  • Bukau, B.
(2008) Biochem Soc Trans, 36, Pt 1, 120-5

Novel insights into the mechanism of chaperone-assisted protein disaggregation

  • Weibezahn, J.
  • Schlieker, C.
  • Tessarz, P.
  • Mogk, A.
  • Bukau, B.
(2005) Biol Chem, 386, 8, 739-44

Thermotolerance requires refolding of aggregated proteins by substrate translocation through the central pore of ClpB

  • Weibezahn, J.
  • Tessarz, P.
  • Schlieker, C.
  • Zahn, R.
  • Maglica, Z.
  • Lee, S.
  • Zentgraf, H.
  • Weber-Ban, E. U.
  • Dougan, D. A.
  • Tsai, F. T.
  • Mogk, A.
  • Bukau, B.
(2004) Cell, 119, 5, 653-65

Substrate recognition by the AAA+ chaperone ClpB

  • Schlieker, C.
  • Weibezahn, J.
  • Patzelt, H.
  • Tessarz, P.
  • Strub, C.
  • Zeth, K.
  • Erbse, A.
  • Schneider-Mergener, J.
  • Chin, J. W.
  • Schultz, P. G.
  • Bukau, B.
  • Mogk, A.
(2004) Nat Struct Mol Biol, 11, 7, 607-15

Inhibition of ubiquitin/proteasome-dependent proteolysis in Saccharomyces cerevisiae by a Gly-Ala repeat

  • Heessen, S.
  • Dantuma, N. P.
  • Tessarz, P.
  • Jellne, M.
  • Masucci, M. G.
(2003) FEBS Lett, 555, 2, 397-404

*gleichwertiger Beitrag; **Korrespondenzautor