Serviceeinheit FACS & Mikroskopie

Publikationen

NIK/MAP3K14 in hepatocytes orchestrates NASH to hepatocellular carcinoma progression via JAK2/STAT5 inhibition

  • Vesting, A. J.
  • Jais, A.
  • Klemm, P.
  • Steuernagel, L.
  • Wienand, P.
  • Fog-Tonnesen, M.
  • Hvid, H.
  • Schumacher, A. L.
  • Kukat, C.
  • Nolte, H.
  • Georgomanolis, T.
  • Altmuller, J.
  • Pasparakis, M.
  • Schmidt, A.
  • Kruger, M.
  • Supprian, M. S.
  • Waisman, A.
  • Straub, B. K.
  • Raschzok, N.
  • Bernier, M.
  • Birkenfeld, A. L.
  • Hovelmeyer, N.
  • Bruning, J. C.
  • Wunderlich, F. T.
(2022) Mol Metab, 66, 101626

Hypoxia promotes osteogenesis by facilitating acetyl-CoA-mediated mitochondrial-nuclear communication

  • Pouikli, A.
  • Maleszewska, M.
  • Parekh, S.
  • Yang, M.
  • Nikopoulou, C.
  • Bonfiglio, J. J.
  • Mylonas, C.
  • Sandoval, T.
  • Schumacher, A. L.
  • Hinze, Y.
  • Matic, I.
  • Frezza, C.
  • Tessarz, P.
(2022) EMBO J, e111239

RNA-sequencing of single cholangiocyte-derived organoids reveals high organoid-to organoid variability

  • Gehling, K.
  • Parekh, S.
  • Schneider, F.
  • Kirchner, M.
  • Kondylis, V.
  • Nikopoulou, C.
  • Tessarz, P.
(2022) Life Sci Alliance, 5, 12

Unraveling Structural Rearrangements of the CFH Gene Cluster in Atypical Hemolytic Uremic Syndrome Patients Using Molecular Combing and Long-Fragment Targeted Sequencing

  • Tschernoster, N.
  • Erger, F.
  • Walsh, P. R.
  • McNicholas, B.
  • Fistrek, M.
  • Habbig, S.
  • Schumacher, A. L.
  • Folz-Donahue, K.
  • Kukat, C.
  • Toliat, M. R.
  • Becker, C.
  • Thiele, H.
  • Kavanagh, D.
  • Nurnberg, P.
  • Beck, B. B.
  • Altmuller, J.
(2022) J Mol Diagn, 24, 6, 619-631

None fits all: Unraveling structural rearrangements of the CFH gene cluster in aHUS patients using molecular combing and long fragment targeted sequencing

  • Tschernoster, N.
  • Erger, F.
  • Walsh, P. R.
  • McNicholas, B.
  • Fistrek, M.
  • Habbig, S.
  • Schumacher, L.
  • Folz-Donahue, K.
  • Kukat, C.
  • Toliat, M. R.
  • Becker, C.
  • Thiele, H.
  • Kavanagh, D.
  • Nuernberg, P.
  • Beck, B.
  • Altmuller, J.
(2022) J Mol Diagn

Chromosome-scale and haplotype-resolved genome assembly of a tetraploid potato cultivar

  • Sun, H.
  • Jiao, W. B.
  • Krause, K.
  • Campoy, J. A.
  • Goel, M.
  • Folz-Donahue, K.
  • Kukat, C.
  • Huettel, B.
  • Schneeberger, K.
(2022) Nat Genet, 54, 3, 342-348

Hypoxia promotes osteogenesis via regulation of the mito-nuclear communication

  • Pouikli, Andromachi
  • Maleszewska, Monika
  • Parekh, Swati
  • Nikopoulou, Chrysa
  • Bonfiglio, Juan-Jose
  • Mylonas, Constantine
  • Sandoval, Tonantzi
  • Schumacher, Anna-Lena
  • Hinze, Yvonne
  • Matic, Ivan
  • Tessarz, Peter
(2022) bioRxiv, 2022.02.26.482117

QUAREP-LiMi: a community endeavor to advance quality assessment and reproducibility in light microscopy

  • Boehm, U.
  • Nelson, G.
  • Brown, C. M.
  • Bagley, S.
  • Bajcsy, P.
  • Bischof, J.
  • Dauphin, A.
  • Dobbie, I. M.
  • Eriksson, J. E.
  • Faklaris, O.
  • Fernandez-Rodriguez, J.
  • Ferrand, A.
  • Gelman, L.
  • Gheisari, A.
  • Hartmann, H.
  • Kukat, C.
  • Laude, A.
  • Mitkovski, M.
  • Munck, S.
  • North, A. J.
  • Rasse, T. M.
  • Resch-Genger, U.
  • Schuetz, L. C.
  • Seitz, A.
  • Strambio-De-Castillia, C.
  • Swedlow, J. R.
  • Nitschke, R.
(2021) Nat Methods, 18, 12, 1423-1426

Single organoid RNA-sequencing reveals high organoid-to-organoid variability

  • Gehling, K.; Parekh, S.; Schneider, F.; Kirchner, M.; Kondylis, V.; Nikopoulou, C.; Tessarz, P.
(2021) bioRxiv, 2021.11.22.469588

Chromatin remodeling due to degradation of citrate carrier impairs osteogenesis of aged mesenchymal stem cells

  • Pouikli, A.
  • Parekh, S.
  • Maleszewska, M.
  • Nikopoulou, C.
  • Baghdadi, M.
  • Tripodi, I.
  • Folz-Donahue, K.
  • Hinze, Y.
  • Mesaros, A.
  • Hoey, D.
  • Giavalisco, P.
  • Dowell, R.
  • Partridge, L.
  • Tessarz, P.
(2021) Nature Aging, 1, 9, 810-825

QUAREP-LiMi: A community-driven initiative to establish guidelines for quality assessment and reproducibility for instruments and images in light microscopy

  • Nelson, G.
  • Boehm, U.
  • Bagley, S.
  • Bajcsy, P.
  • Bischof, J.
  • Brown, C. M.
  • Dauphin, A.
  • Dobbie, I. M.
  • Eriksson, J. E.
  • Faklaris, O.
  • Fernandez-Rodriguez, J.
  • Ferrand, A.
  • Gelman, L.
  • Gheisari, A.
  • Hartmann, H.
  • Kukat, C.
  • Laude, A.
  • Mitkovski, M.
  • Munck, S.
  • North, A. J.
  • Rasse, T. M.
  • Resch-Genger, U.
  • Schuetz, L. C.
  • Seitz, A.
  • Strambio-De-Castillia, C.
  • Swedlow, J. R.
  • Alexopoulos, I.
  • Aumayr, K.
  • Avilov, S.
  • Bakker, G. J.
  • Bammann, R. R.
  • Bassi, A.
  • Beckert, H.
  • Beer, S.
  • Belyaev, Y.
  • Bierwagen, J.
  • Birngruber, K. A.
  • Bosch, M.
  • Breitlow, J.
  • Cameron, L. A.
  • Chalfoun, J.
  • Chambers, J. J.
  • Chen, C. L.
  • Conde-Sousa, E.
  • Corbett, A. D.
  • Cordelieres, F. P.
  • Nery, E. D.
  • Dietzel, R.
  • Eismann, F.
  • Fazeli, E.
  • Felscher, A.
  • Fried, H.
  • Gaudreault, N.
  • Goh, W. I.
  • Guilbert, T.
  • Hadleigh, R.
  • Hemmerich, P.
  • Holst, G. A.
  • Itano, M. S.
  • Jaffe, C. B.
  • Jambor, H. K.
  • Jarvis, S. C.
  • Keppler, A.
  • Kirchenbuechler, D.
  • Kirchner, M.
  • Kobayashi, N.
  • Krens, G.
  • Kunis, S.
  • Lacoste, J.
  • Marcello, M.
  • Martins, G. G.
  • Metcalf, D. J.
  • Mitchell, C. A.
  • Moore, J.
  • Mueller, T.
  • Nelson, M. S.
  • Ogg, S.
  • Onami, S.
  • Palmer, A. L.
  • Paul-Gilloteaux, P.
  • Pimentel, J. A.
  • Plantard, L.
  • Podder, S.
  • Rexhepaj, E.
  • Royon, A.
  • Saari, M. A.
  • Schapman, D.
  • Schoonderwoert, V.
  • Schroth-Diez, B.
  • Schwartz, S.
  • Shaw, M.
  • Spitaler, M.
  • Stoeckl, M. T.
  • Sudar, D.
  • Teillon, J.
  • Terjung, S.
  • Thuenauer, R.
  • Wilms, C. D.
  • Wright, G. D.
  • Nitschke, R.
(2021) J Microsc, 1, 284, 56-73

P2Y6 receptor signaling in natural killer cells impairs insulin sensitivity in obesity

  • Sieben, A.
  • Hausen, A. C.
  • Klemm, P.
  • Jais, A.
  • Heilinger, C.
  • Alber, J.
  • Folz-Donahue, K.
  • Schumacher, L.
  • Altmüller, J.
  • Franitza, M.
  • Giavalisco, P.
  • Hinze, Y.
  • Brodesser, S.
  • Kukat, C.
  • Theurich, S.
  • Brüning, J. C.
(2021) bioRxiv, 2021.06.23.449596

High proliferation and delamination during skin epidermal stratification

  • Damen, M.
  • Wirtz, L.
  • Soroka, E.
  • Khatif, H.
  • Kukat, C.
  • Simons, B. D.
  • Bazzi, H.
(2021) Nature Communications, 12, 1, 3227

Chromosome-scale and haplotype-resolved genome assembly of a tetraploid potato cultivar

  • Sun, H.
  • Jiao, W.-B.
  • Krause, K.
  • Campoy, J. A.
  • Goel, M.
  • Folz-Donahue, K.
  • Kukat, C.
  • Huettel, B.
  • Schneeberger, K.
(2021) bioRxiv, 2021.05.15.444292

Gamete binning: chromosome-level and haplotype-resolved genome assembly enabled by high-throughput single-cell sequencing of gamete genomes

  • Campoy, J. A.
  • Sun, H.
  • Goel, M.
  • Jiao, W. B.
  • Folz-Donahue, K.
  • Wang, N.
  • Rubio, M.
  • Liu, C.
  • Kukat, C.
  • Ruiz, D.
  • Huettel, B.
  • Schneeberger, K.
(2020) Genome Biol, 21, 1, 306

Neuronal metabolic rewiring promotes resilience to neurodegeneration caused by mitochondrial dysfunction

  • Motori, E.
  • Atanassov, I.
  • Kochan, S. M. V.
  • Folz-Donahue, K.
  • Sakthivelu, V.
  • Giavalisco, P.
  • Toni, N.
  • Puyal, J.
  • Larsson, N. G.
(2020) Sci Adv, 6, 35, eaba8271

Cell type-specific transcriptomics of esophageal adenocarcinoma as a scalable alternative for single cell transcriptomics

  • Kramer, M.
  • Plum, P. S.
  • Velazquez Camacho, O.
  • Folz-Donahue, K.
  • Thelen, M.
  • Garcia-Marquez, I.
  • Wolwer, C.
  • Busker, S.
  • Wittig, J.
  • Franitza, M.
  • Altmuller, J.
  • Loser, H.
  • Schlosser, H.
  • Buttner, R.
  • Schroder, W.
  • Bruns, C. J.
  • Alakus, H.
  • Quaas, A.
  • Chon, S. H.
  • Hillmer, A. M.
(2020) Mol Oncol, 14, 6, 1170-1184

A Joint Action in Times of Pandemic: The German BioImaging Recommendations for Operating Imaging Core Facilities During the SARS-Cov-2 Emergency

  • Dietzel, S.
  • Ferrando-May, E.
  • Fried, H.
  • Kukat, C.
  • Naumann, A.
  • Nitschke, R.
  • Pasierbek, P.
  • Peychl, J.
  • Rasse, T. M.
  • Schroth-Diez, B.
  • Stockl, M. T.
  • Terjung, S.
  • Thuenauer, R.
  • Tulok, S.
  • Weidtkamp-Peters, S.
  • German BioImaging-Society for, Microscopy
  • Image, Analysis
(2020) Cytometry A, 9, 97, 882-886

MCH Neurons Regulate Permeability of the Median Eminence Barrier

  • Jiang, H.
  • Gallet, S.
  • Klemm, P.
  • Scholl, P.
  • Folz-Donahue, K.
  • Altmuller, J.
  • Alber, J.
  • Heilinger, C.
  • Kukat, C.
  • Loyens, A.
  • Muller-Fielitz, H.
  • Sundaram, S.
  • Schwaninger, M.
  • Prevot, V.
  • Bruning, J. C.
(2020) Neuron, 2, 107, 205-207

Mitochondria-Endoplasmic Reticulum Contacts in Reactive Astrocytes Promote Vascular Remodeling

  • Goebel, J.
  • Engelhardt, E.
  • Pelzer, P.
  • Sakthivelu, V.
  • Jahn, H. M.
  • Jevtic, M.
  • Folz-Donahue, K.
  • Kukat, C.
  • Schauss, A.
  • Frese, C. K.
  • Giavalisco, P.
  • Ghanem, A.
  • Conzelmann, K. K.
  • Motori, E.
  • Bergami, M.
(2020) Cell Metab, 31, 4, 791-808 e8

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

  • Cossarizza, A.
  • Chang, H. D.
  • Radbruch, A.
  • Acs, A.
  • Adam, D.
  • Adam-Klages, S.
  • Agace, W. W.
  • Aghaeepour, N.
  • Akdis, M.
  • Allez, M.
  • Almeida, L. N.
  • Alvisi, G.
  • Anderson, G.
  • Andra, I.
  • Annunziato, F.
  • Anselmo, A.
  • Bacher, P.
  • Baldari, C. T.
  • Bari, S.
  • Barnaba, V.
  • Barros-Martins, J.
  • Battistini, L.
  • Bauer, W.
  • Baumgart, S.
  • Baumgarth, N.
  • Baumjohann, D.
  • Baying, B.
  • Bebawy, M.
  • Becher, B.
  • Beisker, W.
  • Benes, V.
  • Beyaert, R.
  • Blanco, A.
  • Boardman, D. A.
  • Bogdan, C.
  • Borger, J. G.
  • Borsellino, G.
  • Boulais, P. E.
  • Bradford, J. A.
  • Brenner, D.
  • Brinkman, R. R.
  • Brooks, A. E. S.
  • Busch, D. H.
  • Buscher, M.
  • Bushnell, T. P.
  • Calzetti, F.
  • Cameron, G.
  • Cammarata, I.
  • Cao, X.
  • Cardell, S. L.
  • Casola, S.
  • Cassatella, M. A.
  • Cavani, A.
  • Celada, A.
  • Chatenoud, L.
  • Chattopadhyay, P. K.
  • Chow, S.
  • Christakou, E.
  • Cicin-Sain, L.
  • Clerici, M.
  • Colombo, F. S.
  • Cook, L.
  • Cooke, A.
  • Cooper, A. M.
  • Corbett, A. J.
  • Cosma, A.
  • Cosmi, L.
  • Coulie, P. G.
  • Cumano, A.
  • Cvetkovic, L.
  • Dang, V. D.
  • Dang-Heine, C.
  • Davey, M. S.
  • Davies, D.
  • De Biasi, S.
  • Del Zotto, G.
  • Dela Cruz, G. V.
  • Delacher, M.
  • Della Bella, S.
  • Dellabona, P.
  • Deniz, G.
  • Dessing, M.
  • Di Santo, J. P.
  • Diefenbach, A.
  • Dieli, F.
  • Dolf, A.
  • Dorner, T.
  • Dress, R. J.
  • Dudziak, D.
  • Dustin, M.
  • Dutertre, C. A.
  • Ebner, F.
  • Eckle, S. B. G.
  • Edinger, M.
  • Eede, P.
  • Ehrhardt, G. R. A.
  • Eich, M.
  • Engel, P.
  • Engelhardt, B.
  • Erdei, A.
  • Esser, C.
  • Everts, B.
  • Evrard, M.
  • Falk, C. S.
  • Fehniger, T. A.
  • Felipo-Benavent, M.
  • Ferry, H.
  • Feuerer, M.
  • Filby, A.
  • Filkor, K.
  • Fillatreau, S.
  • Follo, M.
  • Forster, I.
  • Foster, J.
  • Foulds, G. A.
  • Frehse, B.
  • Frenette, P. S.
  • Frischbutter, S.
  • Fritzsche, W.
  • Galbraith, D. W.
  • Gangaev, A.
  • Garbi, N.
  • Gaudilliere, B.
  • Gazzinelli, R. T.
  • Geginat, J.
  • Gerner, W.
  • Gherardin, N. A.
  • Ghoreschi, K.
  • Gibellini, L.
  • Ginhoux, F.
  • Goda, K.
  • Godfrey, D. I.
  • Goettlinger, C.
  • Gonzalez-Navajas, J. M.
  • Goodyear, C. S.
  • Gori, A.
  • Grogan, J. L.
  • Grummitt, D.
  • Grutzkau, A.
  • Haftmann, C.
  • Hahn, J.
  • Hammad, H.
  • Hammerling, G.
  • Hansmann, L.
  • Hansson, G.
  • Harpur, C. M.
  • Hartmann, S.
  • Hauser, A.
  • Hauser, A. E.
  • Haviland, D. L.
  • Hedley, D.
  • Hernandez, D. C.
  • Herrera, G.
  • Herrmann, M.
  • Hess, C.
  • Hofer, T.
  • Hoffmann, P.
  • Hogquist, K.
  • Holland, T.
  • Hollt, T.
  • Holmdahl, R.
  • Hombrink, P.
  • Houston, J. P.
  • Hoyer, B. F.
  • Huang, B.
  • Huang, F. P.
  • Huber, J. E.
  • Huehn, J.
  • Hundemer, M.
  • Hunter, C. A.
  • Hwang, W. Y. K.
  • Iannone, A.
  • Ingelfinger, F.
  • Ivison, S. M.
  • Jack, H. M.
  • Jani, P. K.
  • Javega, B.
  • Jonjic, S.
  • Kaiser, T.
  • Kalina, T.
  • Kamradt, T.
  • Kaufmann, S. H. E.
  • Keller, B.
  • Ketelaars, S. L. C.
  • Khalilnezhad, A.
  • Khan, S.
  • Kisielow, J.
  • Klenerman, P.
  • Knopf, J.
  • Koay, H. F.
  • Kobow, K.
  • Kolls, J. K.
  • Kong, W. T.
  • Kopf, M.
  • Korn, T.
  • Kriegsmann, K.
  • Kristyanto, H.
  • Kroneis, T.
  • Krueger, A.
  • Kuhne, J.
  • Kukat, C.
  • […]
  • Yazdanbakhsh, M.
  • Yu, L.
  • Yue, A.
  • Zhang, H.
  • Zhao, Y.
  • Ziegler, S. M.
  • Zielinski, C.
  • Zimmermann, J.
  • Zychlinsky, A.
(2019) Eur J Immunol, 49, 10, 1457-1973

Individual in vivo Profiles of Microglia Polarization After Stroke, Represented by the Genes iNOS and Ym1

  • Collmann, F. M.
  • Pijnenburg, R.
  • Hamzei-Taj, S.
  • Minassian, A.
  • Folz-Donahue, K.
  • Kukat, C.
  • Aswendt, M.
  • Hoehn, M.
(2019) Front Immunol, 10, 1236

Cyt-Geist: Current and Future Challenges in Cytometry: Reports of the CYTO 2018 Conference Workshops

  • Czechowska, K.
  • Lannigan, J.
  • Wang, L.
  • Arcidiacono, J.
  • Ashhurst, T. M.
  • Barnard, R. M.
  • Bauer, S.
  • Bispo, C.
  • Bonilla, D. L.
  • Brinkman, R. R.
  • Cabanski, M.
  • Chang, H. D.
  • Chakrabarti, L.
  • Chojnowski, G.
  • Cotleur, B.
  • Degheidy, H.
  • Dela Cruz, G. V.
  • Eck, S.
  • Elliott, J.
  • Errington, R.
  • Filby, A.
  • Gagnon, D.
  • Gardner, R.
  • Green, C.
  • Gregory, M.
  • Groves, C. J.
  • Hall, C.
  • Hammes, F.
  • Hedrick, M.
  • Hoffman, R.
  • Icha, J.
  • Ivaska, J.
  • Jenner, D. C.
  • Jones, D.
  • Kerckhof, F. M.
  • Kukat, C.
  • Lanham, D.
  • Leavesley, S.
  • Lee, M.
  • Lin-Gibson, S.
  • Litwin, V.
  • Liu, Y.
  • Molloy, J.
  • Moore, J. S.
  • Muller, S.
  • Nedbal, J.
  • Niesner, R.
  • Nitta, N.
  • Ohlsson-Wilhelm, B.
  • Paul, N. E.
  • Perfetto, S.
  • Portat, Z.
  • Props, R.
  • Radtke, S.
  • Rayanki, R.
  • Rieger, A.
  • Rogers, S.
  • Rubbens, P.
  • Salomon, R.
  • Schiemann, M.
  • Sharpe, J.
  • Sonder, S. U.
  • Stewart, J. J.
  • Sun, Y.
  • Ulrich, H.
  • Van Isterdael, G.
  • Vitaliti, A.
  • van Vreden, C.
  • Weber, M.
  • Zimmermann, J.
  • Vacca, G.
  • Wallace, P.
  • Tarnok, A.
(2019) Cytometry A, 95, 6, 598-644

The in vivo timeline of differentiation of engrafted human neural progenitor cells

  • Vogel, S.
  • Schafer, C.
  • Hess, S.
  • Folz-Donahue, K.
  • Nelles, M.
  • Minassian, A.
  • Schwarz, M. K.
  • Kukat, C.
  • Ehrlich, M.
  • Zaehres, H.
  • Kloppenburg, P.
  • Hoehn, M.
  • Aswendt, M.
(2019) Stem Cell Res, 37, 101429

Cell Cycle Analysis of Hematopoietic Stem and Progenitor Cells by Multicolor Flow Cytometry

  • Galvin, A.
  • Weglarz, M.
  • Folz-Donahue, K.
  • Handley, M.
  • Baum, M.
  • Mazzola, M.
  • Litwa, H.
  • Scadden, D. T.
  • Silberstein, L.
(2019) Curr Protoc Cytom, 87, 1, e50

Imaging Reporter Strategy to Monitor Gene Activation of Microglia Polarisation States under Stimulation

  • Collmann, F. M.
  • Pijnenburg, R.
  • Schneider, G.
  • Schafer, C.
  • Folz-Donahue, K.
  • Kukat, C.
  • Hoehn, M.
(2018) J Neuroimmune Pharmacol, 13, 3, 371-382

Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice

  • Kauppila, J. H. K.
  • Bonekamp, N. A.
  • Mourier, A.
  • Isokallio, M. A.
  • Just, A.
  • Kauppila, T. E. S.
  • Stewart, J. B.
  • Larsson, N. G.
(2018) Nucleic Acids Res, 46, 13, 6642-6669

Increased Total mtDNA Copy Number Cures Male Infertility Despite Unaltered mtDNA Mutation Load

  • Jiang, M.
  • Kauppila, T. E. S.
  • Motori, E.
  • Li, X.
  • Atanassov, I.
  • Folz-Donahue, K.
  • Bonekamp, N. A.
  • Albarran-Gutierrez, S.
  • Stewart, J. B.
  • Larsson, N. G.
(2017) Cell Metab, 26, 2, 429-436 e4

IL-6/Stat3-Dependent Induction of a Distinct, Obesity-Associated NK Cell Subpopulation Deteriorates Energy and Glucose Homeostasis

  • Theurich, S.
  • Tsaousidou, E.
  • Hanssen, R.
  • Lempradl, A. M.
  • Mauer, J.
  • Timper, K.
  • Schilbach, K.
  • Folz-Donahue, K.
  • Heilinger, C.
  • Sexl, V.
  • Pospisilik, J. A.
  • Wunderlich, F. T.
  • Bruning, J. C.
(2017) Cell Metab, 26, 1, 171-184 e6

Highly Expandable Human iPS Cell-Derived Neural Progenitor Cells (NPC) and Neurons for Central Nervous System Disease Modeling and High-Throughput Screening

  • Cheng, C.
  • Fass, D. M.
  • Folz-Donahue, K.
  • MacDonald, M. E.
  • Haggarty, S. J.
(2017) Curr Protoc Hum Genet, 92, 21 8 1-21 8 21

Advanced light microscopy core facilities: Balancing service, science and career

  • Ferrando-May, E.
  • Hartmann, H.
  • Reymann, J.
  • Ansari, N.
  • Utz, N.
  • Fried, H. U.
  • Kukat, C.
  • Peychl, J.
  • Liebig, C.
  • Terjung, S.
  • Laketa, V.
  • Sporbert, A.
  • Weidtkamp-Peters, S.
  • Schauss, A.
  • Zuschratter, W.
  • Avilov, S.
  • German BioImaging, network
(2016) Microsc Res Tech, 79, 6, 463-79

Cross-strand binding of TFAM to a single mtDNA molecule forms the mitochondrial nucleoid

  • Kukat, C.
  • Davies, K. M.
  • Wurm, C. A.
  • Spahr, H.
  • Bonekamp, N. A.
  • Kuhl, I.
  • Joos, F.
  • Polosa, P. L.
  • Park, C. B.
  • Posse, V.
  • Falkenberg, M.
  • Jakobs, S.
  • Kuhlbrandt, W.
  • Larsson, N. G.
(2015) Proc Natl Acad Sci U S A, 112, 36, 11288-93

SLIRP Regulates the Rate of Mitochondrial Protein Synthesis and Protects LRPPRC from Degradation

  • Lagouge, M.
  • Mourier, A.
  • Lee, H. J.
  • Spahr, H.
  • Wai, T.
  • Kukat, C.
  • Silva Ramos, E.
  • Motori, E.
  • Busch, J. D.
  • Siira, S.
  • German Mouse Clinic, Consortium
  • Kremmer, E.
  • Filipovska, A.
  • Larsson, N. G.
(2015) PLoS Genet, 11, 8, e1005423

Drosophila melanogaster LRPPRC2 is involved in coordination of mitochondrial translation

  • Baggio, F.
  • Bratic, A.
  • Mourier, A.
  • Kauppila, T. E.
  • Tain, L. S.
  • Kukat, C.
  • Habermann, B.
  • Partridge, L.
  • Larsson, N. G.
(2014) Nucleic Acids Res, 42, 22, 13920-38

A multimerized form of recombinant human CD40 ligand supports long-term activation and proliferation of B cells

  • Garcia-Marquez, M. A.
  • Shimabukuro-Vornhagen, A.
  • Theurich, S.
  • Kochanek, M.
  • Weber, T.
  • Wennhold, K.
  • Dauben, A.
  • Dzionek, A.
  • Reinhard, C.
  • von Bergwelt-Baildon, M.
(2014) Cytotherapy, 16, 11, 1537-44

POLRMT does not transcribe nuclear genes

  • Kuhl, I.
  • Kukat, C.
  • Ruzzenente, B.
  • Milenkovic, D.
  • Mourier, A.
  • Miranda, M.
  • Koolmeister, C.
  • Falkenberg, M.
  • Larsson, N. G.
(2014) Nature, 514, 7521, E7-11

mtDNA makes a U-turn for the mitochondrial nucleoid

  • Kukat, C.
  • Larsson, N. G.
(2013) Trends Cell Biol, 23, 9, 457-63

MTERF1 binds mtDNA to prevent transcriptional interference at the light-strand promoter but is dispensable for rRNA gene transcription regulation

  • Terzioglu, M.
  • Ruzzenente, B.
  • Harmel, J.
  • Mourier, A.
  • Jemt, E.
  • Lopez, M. D.
  • Kukat, C.
  • Stewart, J. B.
  • Wibom, R.
  • Meharg, C.
  • Habermann, B.
  • Falkenberg, M.
  • Gustafsson, C. M.
  • Park, C. B.
  • Larsson, N. G.
(2013) Cell Metab, 17, 4, 618-26

MTERF3 regulates mitochondrial ribosome biogenesis in invertebrates and mammals

  • Wredenberg, A.
  • Lagouge, M.
  • Bratic, A.
  • Metodiev, M. D.
  • Spahr, H.
  • Mourier, A.
  • Freyer, C.
  • Ruzzenente, B.
  • Tain, L.
  • Gronke, S.
  • Baggio, F.
  • Kukat, C.
  • Kremmer, E.
  • Wibom, R.
  • Polosa, P. L.
  • Habermann, B.
  • Partridge, L.
  • Park, C. B.
  • Larsson, N. G.
(2013) PLoS Genet, 9, 1, e1003178

The bicoid stability factor controls polyadenylation and expression of specific mitochondrial mRNAs in Drosophila melanogaster

  • Bratic, A.
  • Wredenberg, A.
  • Gronke, S.
  • Stewart, J. B.
  • Mourier, A.
  • Ruzzenente, B.
  • Kukat, C.
  • Wibom, R.
  • Habermann, B.
  • Partridge, L.
  • Larsson, N. G.
(2011) PLoS Genet, 7, 10, e1002324

Nitric oxide-associated protein 1 (NOA1) is necessary for oxygen-dependent regulation of mitochondrial respiratory complexes

  • Heidler, J.
  • Al-Furoukh, N.
  • Kukat, C.
  • Salwig, I.
  • Ingelmann, M. E.
  • Seibel, P.
  • Kruger, M.
  • Holtz, J.
  • Wittig, I.
  • Braun, T.
  • Szibor, M.
(2011) J Biol Chem, 286, 37, 32086-93

Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA

  • Kukat, C.
  • Wurm, C. A.
  • Spahr, H.
  • Falkenberg, M.
  • Larsson, N. G.
  • Jakobs, S.
(2011) Proc Natl Acad Sci U S A, 108, 33, 13534-9

MTERF4 regulates translation by targeting the methyltransferase NSUN4 to the mammalian mitochondrial ribosome

  • Camara, Y.
  • Asin-Cayuela, J.
  • Park, C. B.
  • Metodiev, M. D.
  • Shi, Y.
  • Ruzzenente, B.
  • Kukat, C.
  • Habermann, B.
  • Wibom, R.
  • Hultenby, K.
  • Franz, T.
  • Erdjument-Bromage, H.
  • Tempst, P.
  • Hallberg, B. M.
  • Gustafsson, C. M.
  • Larsson, N. G.
(2011) Cell Metab, 13, 5, 527-39

Tight control of mitochondrial membrane potential by cytochrome c oxidase

  • Pacelli, C.
  • Latorre, D.
  • Cocco, T.
  • Capuano, F.
  • Kukat, C.
  • Seibel, P.
  • Villani, G.
(2011) Mitochondrion, 11, 2, 334-41

Cosegregation of novel mitochondrial 16S rRNA gene mutations with the age-associated T414G variant in human cybrids

  • Seibel, P.
  • Di Nunno, C.
  • Kukat, C.
  • Schafer, I.
  • Del Bo, R.
  • Bordoni, A.
  • Comi, G. P.
  • Schon, A.
  • Capuano, F.
  • Latorre, D.
  • Villani, G.
(2008) Nucleic Acids Res, 36, 18, 5872-81

Generation of rho0 cells utilizing a mitochondrially targeted restriction endonuclease and comparative analyses

  • Kukat, A.
  • Kukat, C.
  • Brocher, J.
  • Schafer, I.
  • Krohne, G.
  • Trounce, I. A.
  • Villani, G.
  • Seibel, P.
(2008) Nucleic Acids Res, 36, 7, e44

Publikationen in denen die Core Facility FACS & Mikroskopie in den "Acknowledgments" aufgeführt wird

Burr SP, Klimm F, Glynos A, Prater M, Sendon P, Nash P, Powell CA, Simard ML, Bonekamp NA, Charl J, Diaz H, Bozhilova LV, Nie Y, Zhang H, Frison M, Falkenberg M, Jones N, Minczuk M, Stewart JB, Chinnery PF. (2023) Cell lineage-specific mitochondrial resilience during mammalian organogenesis.Cell. 2023 Feb 17:S0092-8674(23)00093-4.

Ripa R, Ballhysa E, Steiner JD, Annibal A, Hochhard N, Latza C, Dolfi L, Calabrese C, Meyer AM, Polidori MC, Müller RU, Antebi A (2022) Refeeding-associated AMPKy1 complex activity is a hallmark of health and longevity. bioRxiv 2022.12.05.519139

Gross AS, Ghillebert R, Schuetter M, Reinartz E, Rowland A, Graef M (2022) A metabolite sensor subunit of the Atg1/ULK complex regulates selective autophagy.bioRxiv 2022.12.13.520293

Artoni F, Grützmacher N, Demetriades C (2022) Comprehensive Evaluation of Rapamycin’s Specificity as an mTOR Inhibitor. bioRxiv 2022.12.10.519872

Kieckhöfer E, Slaats GG, Ebert LK, Albert MC, Dafinger C, Kashkar H, Benzing T, Schermer B. (2022) Primary cilia suppress Ripk3-mediated necroptosis.Cell Death Discov. 2022 Dec 2;8(1):477.

Regan JC, Lu YX, Ureña E, Meilenbrock RL, Catterson JH, Kißler D, Fröhlich J, Funk E, Partridge L (2022) Sexual identity of enterocytes regulates autophagy to determine intestinal health, lifespan and responses to rapamycin. Nat Aging 2, 1145–1158

Nicastro R, Brohée L, Alba J, Nüchel J, Figlia G, Kipschull S, Gollwitzer P, Romero-Pozuelo J, Fernandes SA, Lamprakis A, Vanni S, Teleman AA, De Virgilio C, Demetriades C (2022) Malonyl-CoA is an ancient physiological ATP-competitive mTORC1 inhibitor.bioRxiv 2022.11.06.515351

Dabrowski R, Tulli S, Graef M (2022) Parallel phospholipid transfer by Vps13 and Atg2 determines autophagosome biogenesis dynamics. bioRxiv 2022.11.10.516013

Flümann R, Hansen J, Pelzer BW, Nieper P, Lohmann T, Kisis I, Riet T, Kohlhas V, Nguyen PH, Peifer M, Abedpour N, Bosco G, Thomas RK, Kochanek M, Knüfer J, Jonigkeit L, Beleggia F, Holzem A, Büttner R, Lohneis P, Meinel J, Ortmann M, Persigehl T, Hallek M, Calado DP, Chmielewski M, Klein S, Göthert JR, Chapuy B, Zevnik B, Wunderlich FT, von Tresckow B, Jachimowicz RD, Melnick AM, Reinhardt HC, Knittel G. (2023) Distinct Genetically Determined Origins of Myd88/BCL2-Driven Aggressive Lymphoma Rationalize Targeted Therapeutic Intervention Strategies. Blood Cancer Discov. 2023 Jan 6;4(1):78-97.

Pouikli A, Maleszewska M, Parekh S, Yang M, Nikopoulou C, Bonfiglio JJ, Mylonas C, Sandoval T, Schumacher AL, Hinze Y, Matic I, Frezza C, Tessarz P. (2022) Hypoxia promotes osteogenesis by facilitating acetyl-CoA-mediated mitochondrial-nuclear communication.EMBO J. 2022 Dec 1;41(23):e111239.

Huang, W., Kew, C., Fernandes, S. d. A., Löhrke, A., Han, L., Demetriades, C., and Antebi, A. (2022) Decreased spliceosome fidelity and egl-8 intron retention inhibit mTORC1 signaling to promote longevity. Nature Aging 2, 796-808

Ahola, S., Rivera Mejias, P., Hermans, S., Chandragiri, S., Giavalisco, P., Nolte, H., and Langer, T. (2022) OMA1-mediated integrated stress response protects against ferroptosis in mitochondrial cardiomyopathy. Cell Metab

Gollwitzer, P., Grutzmacher, N., Wilhelm, S., Kummel, D., and Demetriades, C. (2022) A Rag GTPase dimer code defines the regulation of mTORC1 by amino acids. Nat Cell Biol 24, 1394-1406

Bozukova, M., Nikopoulou, C., Kleinenkuhnen, N., Grbavac, D., Goetsch, K., and Tessarz, P. (2022) Aging is associated with increased chromatin accessibility and reduced polymerase pausing in liver. Molecular Systems Biology 18, e11002

Juricic, P., Lu, Y.-X., Leech, T., Drews, L. F., Paulitz, J., Lu, J., Nespital, T., Azami, S., Regan, J. C., Funk, E., Fröhlich, J., Grönke, S., and Partridge, L. (2022) Long-lasting geroprotection from brief rapamycin treatment in early adulthood by persistently increased intestinal autophagy. Nature Aging 2, 824-836

Zhang, P., Catterson, J. H., Grönke, S., and Partridge, L. (2022) Inhibition of S6K lowers age-related inflammation and immunosenescence and increases lifespan through the endolysosomal system. bioRxiv, 2022.2008.2025.505264

Patron, M., Tarasenko, D., Nolte, H., Kroczek, L., Ghosh, M., Ohba, Y., Lasarzewski, Y., Ahmadi, Z. A., Cabrera-Orefice, A., Eyiama, A., Kellermann, T., Rugarli, E. I., Brandt, U., Meinecke, M., and Langer, T. (2022) Regulation of mitochondrial proteostasis by the proton gradient. EMBO J 41, e110476

Gehling, K., Parekh, S., Schneider, F., Kirchner, M., Kondylis, V., Nikopoulou, C., and Tessarz, P. (2022) RNA-sequencing of single cholangiocyte-derived organoids reveals high organoid-to organoid variability. Life Sci Alliance 5

Ratz L, Brambillasca C, Bartke L, Huetzen MA, Goergens J, Leidecker O, Jachimowicz RD, van de Ven M, Proost N, Siteur B, de Korte-Grimmerink R, Bouwman P, Pulver EM, de Bruijn R, Isensee J, Hucho T, Pandey G, van Lohuizen M, Mallmann P, Reinhardt HC, Jonkers J, Puppe J (2022) Combined inhibition of EZH2 and ATM is synthetic lethal in BRCA1-deficient breast cancer. Breast Cancer Res. 2022 Jun 17;24(1):41

Milenkovic D, Sanz-Moreno A, Calzada-Wack J, Rathkolb B, Veronica Amarie O, Gerlini R, Aguilar-Pimentel A, Misic J, Simard ML, Wolf E, Fuchs H, Gailus-Durner V, de Angelis MH, Larsson NG (2022) Mice lacking the mitochondrial exonuclease MGME1 develop inflammatory kidney disease with glomerular dysfunction. PLoS Genet. 2022 May 9;18(5):e1010190

Juricic P, Lu Y-X, Leech T, Drews LF, Paulitz J, Lu J, Nespital T, Azami S, Regan JC, Funk E, Fröhlich J, Grönke S, and Partridge L (2022) Full geroprotection from brief rapamycin treatment by persistently increased intestinal autophagy. bioRxiv: 2022.2004.2020.488884

Pouikli A, Maleszewska M, Parekh S, Nikopoulou C, Bonfiglio J-J, Mylonas C, Sandoval T, Schumacher A-L, Hinze Y, Matic I, Tessarz P (2022) Hypoxia promotes osteogenesis via regulation of the mito-nuclear communication.bioRxiv: 2022.2002.2026.482117

Kroef V, Ruegenberg S, Horn M, Allmeroth K, Ebert L, Bozkus S, Miethe S, Elling U, Schermer B, Baumann U, Denzel MS (2022) GFPT2/GFAT2 and AMDHD2 act in tandem to control the hexosamine pathway.Elife. 2022 Mar 1;11:e69223

Overhoff M, Tellkamp F, Hess S, Tutas J, Tolve M, Faerfers M, Ickert L, Mohammadi M, De Bruyckere E, Kallergi E, Dell Vedove A, Nikoletopoulou V, Wirth B, Isensee J, Hucho T, Puchkov D, Isbrandt D, Krüger M, Kloppenburg P, Kononenko NL (2022) Autophagy regulates neuronal excitability by controlling cAMP/Protein Kinase A signaling.bioRxiv 2022.02.11.480034

Li X, Straub J, Medeiros TC, Mehra C, Brave Fd, Peker E, Atanassov I, Stillger K, Michaelis JB, Burbridge E, Adrain C, Münch C, Riemer J, Becker T, Pernas LF (2022) Mitochondria shed their outer membrane in response to infection-induced stress.Science 375(6577):eabi4343

Nikopoulou C, Kleinenkuhnen N, Parekh S, Sandoval T, Schneider F, Giavalisco P, Bozukova M, Vesting AJ, Altmüller J, Wunderlich T, Kondylis V, Tresch A, Tessarz P (2021) Single-cell resolution unravels spatial alterations in metabolism, transcriptome and epigenome of ageing liver. bioRxiv: 2021.2012.2014.472593

Patron M, Tarasenko D, Nolte H, Ghosh M, Ohba Y, Lasarzewski Y, Ahmadi ZA, Cabrera-Orefice A, Eyiama A, Kellermann T, Rugarli EI, Brandt U, Meinecke M, Langer T (2021). Regulation of mitochondrial proteostasis by the proton gradient.bioRxiv, 2021.2012.2012.470907

Gehling K, Parekh S, Schneider S, Kirchner M, Kondylis V, Nikopoulou C, Tessarz P. (2021) Single organoid RNA-sequencing reveals high organoid-to-organoid variability. bioRxiv 2021.11.22.469588

Lengefeld J, Cheng CW, Maretich P, Blair M, Hagen H, McReynolds MR, Sullivan E, Majors K, Roberts C, Kang JH, Steiner JD, Miettinen TP, Manalis SR, Antebi A, Morrison SJ, Lees JA, Boyer LA, Yilmaz ÖH, Amon A. (2021) Cell size is a determinant of stem cell potential during aging.Sci Adv. 2021 Nov 12;7(46):eabk0271

Theobald SJ, Gräb J, Fritsch M, Suárez I, Eisfeld HS, Winter S, Koch M, Hölscher C, Pasparakis M, Kashkar H, Rybniker J. (2021) Gasdermin D mediates host cell death but not interleukin-1β secretion in Mycobacterium tuberculosis-infected macrophages.Cell Death Discov. 2021 Oct 30;7(1):327

Regan JC, Lu YX, Ureña E, Meilenbrock R, Catterson JH, Kißler D, Partridge L. (2021) Sexual identity of enterocytes regulates rapamycin-mediated intestinal homeostasis and lifespan extension.bioRxiv 2021.10.22.465415

Ebert LK, Bargfrede S, Bohl K, Müller RU, Benzing T, Schermer B. (2021) JADE family proteins regulate proteasome abundance and activity.bioRxiv 2021.10.01.462752

Pouikli A, Parekh S, Maleszewska M, Nikopoulou C, Baghdadi M, Tripodi I, Folz-Donahue K, Hinze Y, Mesaros A, Hoey D, Giavalisco P, Dowell R, Partridge L, Tessarz P. (2021) Chromatin remodeling due to degradation of citrate carrier impairs osteogenesis of aged mesenchymal stem cells.Nat Aging 1, 810–825 (2021)

Bonekamp NA, Jiang M, Motori E, Garcia Villegas R, Koolmeister C, Atanassov I, Mesaros A, Park CB, Larsson NG. (2021) High levels of TFAM repress mammalian mitochondrial DNA transcription in vivo.Life Sci Alliance. 2021 Aug 30;4(11):e202101034

Dolfi L, Suen TK, Ripa R, Antebi A. (2021) Sperm cryopreservation and in vitro fertilization techniques for the African turquoise killifish Nothobranchius furzeri. Sci Rep. 2021 Aug 25;11(1):17145

Guerrero GA, Derisbourg MJ, Mayr FA, Wester LE, Giorda M, Dinort JE, Hartman MD, Schilling K, Alonso-De Gennaro MJ, Lu RJ, Benayoun BA, Denzel MS. (2021) NHR-8 and P-glycoproteins uncouple xenobiotic resistance from longevity in chemosensory C. elegans mutants.Elife. 2021 Aug 27;10:e53174

Geueke A, Mantellato G, Kuester F, Schettina P, Nelles M, Seeger JM, Kashkar H, Niemann C. (2021) The anti-apoptotic Bcl-2 protein regulates hair follicle stem cell function. EMBO Rep. 2021 Oct 5;22(10):e52301

Schiffer I, Gerisch B, Kawamura K, Laboy R, Hewitt J, Denzel MS, Mori MA, Vanapalli S, Shen Y, Symmons O, Antebi A. (2021) miR-1 coordinately regulates lysosomal v-ATPase and biogenesis to impact proteotoxicity and muscle function during aging. Elife. 2021 Jul 27;10:e66768

Kochan DZ, Mawer JSP, Massen J, Tishinov K, Parekh S, Graef M, Spang A, Tessarz P. (2021) The RNA-binding protein Puf5 contributes to buffering of mRNA upon chromatin-mediated changes in nascent transcription. J Cell Sci. 2021 Jul 14:jcs.259051

Koester J, Miroshnikova YA, Ghatak S, Chacón-Martínez CA, Morgner J, Li X, Atanassov I, Altmüller J, Birk DE, Koch M, Bloch W, Bartusel M, Niessen CM, Rada-Iglesias A, Wickström SA. (2021) Niche stiffening compromises hair follicle stem cell potential during ageing by reducing bivalent promoter accessibility. Nat Cell Biol. 2021 Jul 8

Jiang M, Xie X, Zhu X, Jiang S, Milenkovic D, Misic J, Shi Y, Tandukar N, Li X, Atanassov I, Jenninger L, Hoberg E, Albarran-Gutierrez S, Szilagyi Z, Macao B, Siira SJ, Carelli V, Griffith JD, Gustafsson CM, Nicholls TJ, Filipovska A, Larsson NG, Falkenberg M. (2021) The mitochondrial single-stranded DNA binding protein is essential for initiation of mtDNA replication. Sci Adv. 2021 Jul 2;7(27):eabf8631

Miroshnikova YA, Manet S, Li X, Wickström SA, Faurobert E, Albiges-Rizo C (2021) Calcium signaling mediates a biphasic mechanoadaptive response of endothelial cells to cyclic mechanical stretch. Mol Biol Cell. 2021 Jun 3

Lu YX, Regan JC, Eßer J, Drews LF, Weinseis T, Stinn J, Hahn O, Miller RA, Grönke S, Partridge L (2021) A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageing.Elife. 2021 May 14

Behrends J, Schwager C, Hein M, Scholzen T, Kull S, Jappe U. (2021) Innovative robust basophil activation test using a novel gating strategy reliably diagnosing allergy with full automation. Allergy. 2021 May 11

Allmeroth K, Kim CS, Annibal A, Pouikli A, Koester J, Derisbourg MJ, Andrés Chacón-Martínez C, Latza C, Antebi A, Tessarz P, Wickström SA, Denzel MS (2021) N1-acetylspermidine is a determinant of hair follicle stem cell fate.J Cell Sci. 2021 May 1;134(9)

Sprenger HG, MacVicar T, Bahat A, Fiedler KU, Hermans S, Ehrentraut D, Ried K, Milenkovic D, Bonekamp N, Larsson NG, Nolte H, Giavalisco P, Langer T. (2021) Cellular pyrimidine imbalance triggers mitochondrial DNA-dependent innate immunity. Nat Metab. 2021 Apr 26

Kroef V, Ruegenberg S, Horn M, Allmeroth K, Ebert L, Bozkus S, Miethe S, Schermer B, Baumann U, Denzel MS (2021) GFAT2 and AMDHD2 act in tandem to control the hexosamine biosynthetic pathway.  bioRxiv 2021.04.23.441115

Tain LS, Sehlke R, Meilenbrock RL, Leech T, Paulitz J, Chokkalingam M, Nagaraj N, Grönke S, Fröhlich J, Atanassov I, Mann M, Beyer A, Partridge L. (2021) Tissue-specific modulation of gene expression in response to lowered insulin signalling in Drosophila.  Elife. 2021 Apr 21;10:e67275

L Dolfi, TK Suen, R Ripa, A Antebi (2021) Sperm cryopreservation and in vitro fertilization techniques for the African turquoise killifish Nothobranchius furzeri.Research Square

Schiffer I, Gerisch B, Kawamura K, Laboy R, Hewitt J, Denzel MS, Mori MA, Vanapalli S, Shen Y, Symmons O, Antebi A (2021) miR-1 coordinately regulates lysosomal v-ATPase and biogenesis to affect muscle contractility upon proteotoxic challenge during ageing.  bioRxiv 2021.01.21.427623

Lu J, Temp U, Müller-Hartmann A, Esser J, Grönke S, Partridge L (2021) Sestrin is a key regulator of stem cell function and lifespan in response to dietary amino acids.  Nature Aging 1, 60–72 (2021)

Bonfiglio JJ, Leidecker O, Dauben H, Longarini EJ, Colby T, San Segundo-Acosta P, Perez KA, Matic I. (2020) An HPF1/PARP1-Based Chemical Biology Strategy for Exploring ADP-Ribosylation.Cell. 2020 Nov 12;183(4):1086-1102.e23

Motori E, Atanassov I, Kochan SMV, Folz-Donahue K, Sakthivelu V, Giavalisco P, Toni N, Puyal J, Larsson NG. (2020) Neuronal metabolic rewiring promotes resilience to neurodegeneration caused by mitochondrial dysfunction.Sci Adv. 2020 Aug 28;6(35):eaba8271

Kim CS, Ding X, Allmeroth K, Biggs LC, Kolenc OI, L'Hoest N, Chacón-Martínez CA, Edlich-Muth C, Giavalisco P, Quinn KP, Denzel MS, Eming SA, Wickström SA. (2020) Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle.Cell Metab. 2020 Oct 6;32(4):629-642.e8

Cui D, Mesaros A, Burdeos G, Voigt I, Giavalisco P, Hinze Y, Purrio M, Neumaier B, Drzezga A, Obata Y, Endepols H, Xu X. (2020) Dnmt3a2/Dnmt3L Overexpression in the Dopaminergic System of Mice Increases Exercise Behavior through Signaling Changes in the Hypothalamus.Int J Mol Sci. 2020 Aug 31;21(17):6297

Steven P, Schwab S, Kiesewetter A, Saban DR, Stern ME, Gehlsen U. (2020) Disease-Specific Expression of Conjunctiva Associated Lymphoid Tissue (CALT) in Mouse Models of Dry Eye Disease and Ocular Allergy. Int J Mol Sci. 2020 Oct 12;21(20):E7514

Kochan DZ, Mawer JSP, Tishinov K, Parekh S, Massen J, Graef M, Spang A, Tessarz P (2020) The RNA-binding protein Puf5 buffers mRNA levels against chromatin-mediated changes in nascent transcription. bioRxiv 10.1101/2020.08.13.249912

Dolfi L, Suen TK, Ripa R, Antebi A (2020) Optimization of cryopreservation and in vitro fertilization techniques for the African turquoise killifish Nothobranchius furzeri. bioRxiv 10.1101/2020.04.14.040824

Allmeroth K, Horn M, Kroef V, Miethe S, Müller RU, Denzel MS. (2020) Bortezomib resistance mutations in PSMB5 determine response to second-generation proteasome inhibitors in multiple myeloma. Leukemia. 2020 Jul 20

Damen M, Soroka E, Khatif H, Kukat C, Simons BD, Bazzi H (2020) Epidermal stratification is uncoupled from centrosome-dependent cell division orientation of the basal progenitors.bioRxiv 10.1101/2020.07.24.219493

Alsina D, Lytovchenko O, Schab A, Atanassov I, Schober FA, Jiang M, Koolmeister C, Wedell A, Taylor RW, Wredenberg A, Larsson NG. (2020) FBXL4 deficiency increases mitochondrial removal by autophagy.EMBO Mol Med. 2020 Jul 7;12(7):e11659

Tharyan RG, Annibal A, Schiffer I, Laboy R, Atanassov I, Weber AL, Gerisch B, Antebi A. (2020) NFYB-1 regulates mitochondrial function and longevity via lysosomal prosaposin.Nat Metab. 2020 May;2(5):387-396

Gerisch, B., Tharyan, R. G., Mak, J., Denzel, S. I., Popkes-van Oepen, T., Henn, N., & Antebi, A. (2020). HLH-30/TFEB Is a Master Regulator of Reproductive Quiescence. Developmental cell, 53(3), 316–329.e5

Nava, M. M., Miroshnikova, Y. A., Biggs, L. C., Whitefield, D. B., Metge, F., Boucas, J., Vihinen, H., Jokitalo, E., Li, X., García Arcos, J. M., Hoffmann, B., Merkel, R., Niessen, C. M., Dahl, K. N., & Wickström, S. A. (2020). Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage.Cell, 181(4), 800–817.e22

Ruegenberg, S., Horn, M., Pichlo, C., Allmeroth, K., Baumann, U., & Denzel, M. S. (2020). Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis.Nature communications, 11(1), 687

Schütter, M., Giavalisco, P., Brodesser, S., & Graef, M. (2020). Local Fatty Acid Channeling into Phospholipid Synthesis Drives Phagophore Expansion during Autophagy. Cell, 180(1), 135–149.e14

Morón-Oset, J., Supèr, T., Esser, J., Isaacs, A. M., Grönke, S., & Partridge, L. (2019). Glycine-alanine dipeptide repeats spread rapidly in a repeat length- and age-dependent manner in the fly brain.Acta neuropathologica communications, 7(1), 209

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Tain, L. S., Jain, C., Nespital, T., Froehlich, J., Hinze, Y., Grönke, S., & Partridge, L. (2020). Longevity in response to lowered insulin signaling requires glycine N-methyltransferase-dependent spermidine production.Aging cell, 19(1), e13043

Busch, J. D., Cipullo, M., Atanassov, I., Bratic, A., Silva Ramos, E., Schöndorf, T., Li, X., Pearce, S. F., Milenkovic, D., Rorbach, J., & Larsson, N. G. (2019). MitoRibo-Tag Mice Provide a Tool for In Vivo Studies of Mitoribosome Composition.Cell reports, 29(6), 1728–1738.e9

Guerrero GA, Schilling K, Mayr FAMC, Lu R, Benayoun BA, Denzel MS (2019) NHR-8 regulated P-glycoproteins uncouple xenobiotic stress resistance from longevity in chemosensory C. elegans mutants.bioRxiv 823302

Korzelius, J., Azami, S., Ronnen-Oron, T., Koch, P., Baldauf, M., Meier, E., Rodriguez-Fernandez, I. A., Groth, M., Sousa-Victor, P., & Jasper, H. (2019). The WT1-like transcription factor Klumpfuss maintains lineage commitment of enterocyte progenitors in the Drosophila intestine.Nature communications, 10(1), 4123

Silva Ramos E, Motori E, Brüser C, Kühl I, Yeroslaviz A, Ruzzenente B, Kauppila JHK, Busch JD, Hultenby K, Habermann BH, Jakobs S, Larsson NG, Mourier A. (2019) Mitochondrial fusion is required for regulation of mitochondrial DNA replication. PLoS Genet. 2019 Jun 6;15(6):e1008085

Weigelt CM, Hahn O, Arlt K, Gruhn M, Jahn AJ, Eßer J, Werner JA, Klein C, Büschges A, Grönke S, Partridge L. (2019) Loss of miR-210 leads to progressive retinal degeneration in Drosophila melanogaster.Life Sci Alliance. 2019 Jan 22;2(1). pii: e201800149

Mylonas C, Tessarz P (2018) Transcriptional repression by FACT is linked to regulation of chromatin accessibility at the promoter of ES cells.Life Sci Alliance. 2018 Jun 13;1(3):e201800085

Kauppila JHK, Bonekamp NA, Mourier A, Isokallio MA, Just A, Kauppila TES, Stewart JB, Larsson NG (2018) Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice.Nucleic Acids Res. 2018 Jul 27;46(13):6642-6669

Simard ML, Mourier A, Greaves LC, Taylor RW, Stewart JB (2018) A novel histochemistry assay to assess and quantify focal cytochrome c oxidase deficiency.J Pathol. 2018 Jul;245(3):311-323

Mo D, Cui D, Li X (2018) The role of Aß circRNA in Alzheimer’s disease: alternative mechanism of Aß biogenesis from Aß circRNA translation.bioRxiv

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Horn M, Kroef V, Allmeroth K, Schuller N, Miethe S, Peifer M, Elling U, Penninger JM,  Denzel MS (2018) Unbiased compound-protein interface mapping and prediction of chemoresistance loci through forward genetics in haploid stem cells.Oncotarget January 23, 2018

Miroshnikova YA, Le HQ, Schneider D, Thalheim T, Rübsam M, Bremicker N, Polleux J, Kamprad N, Tarantola M, Wang I, Balland M, Niessen CM, Galle J, Wickström SA (2017) Adhesion forces and cortical tension couple cell proliferation and differentiation to drive epidermal stratification.Nat Cell Biol. 2017

Kohli, P., Höhne, M., Jüngst, C., Bertsch, S., Ebert, L. K., Schauss, A. C., Benzing, T., Rinschen, M. M., & Schermer, B. (2017). The ciliary membrane-associated proteome reveals actin-binding proteins as key components of cilia.EMBO reports, 18(9), 1521–1535

Gorsky MK, Burnouf S, Sofola-Adesakin O, Dols J, Augustin H, Weigelt CM, Grönke S, Partridge L (2017) Pseudo-acetylation of multiple sites on human Tau proteins alters Tau phosphorylation and microtubule binding, and ameliorates amyloid beta toxicity.Sci Rep. 2017 Aug 30;7(1):9984

Jiang M, Kauppila TES, Motori E, Li X, Atanassov I, Folz-Donahue K, Bonekamp NA, Albarran-Gutierrez S, Stewart JB, Larsson NG (2017) Increased Total mtDNA Copy Number Cures Male Infertility Despite Unaltered mtDNA Mutation Load.Cell Metab. 2017 Aug 1;26(2):429-436.e4

Kohli P, Höhne M, Jüngst C, Bertsch S, Ebert LK, Schauss AC, Benzing T, Rinschen MM, Schermer B (2017) The ciliary membrane-associated proteome reveals actin-binding proteins as key components of cilia.EMBO Rep. 2017 Jul 14. pii: e201643846

Theurich S, Tsaousidou E, Hanssen R, Lempradl AM, Mauer J, Timper K, Schilbach K, Folz-Donahue K, Heilinger C, Sexl V, Pospisilik JA, Wunderlich FT, Brüning JC (2017) IL-6/Stat3-Dependent Induction of a Distinct, Obesity-Associated NK Cell Subpopulation Deteriorates Energy and Glucose Homeostasis.Cell Metab. 2017 Jul 5;26(1):171-184.e6

Chacón-Martínez CA, Klose M, Niemann C, Glauche I, Wickström SA (2016) Hair follicle stem cell cultures reveal self-organizing plasticity of stem cells and their progeny.EMBO J. 2017 Jan 17;36(2):151-164

Kauppila JH, Baines HL, Bratic A, Simard ML, Freyer C, Mourier A, Stamp C, Filograna R, Larsson NG, Greaves LC, Stewart JB (2016) A Phenotype-Driven Approach to Generate Mouse Models with Pathogenic mtDNA Mutations Causing Mitochondrial Disease. Cell Rep. 2016 Sep 13;16(11):2980-2990

Kühl I, Miranda M, Posse V, Milenkovic D, Mourier A, Siira SJ, Bonekamp NA, Neumann U, Filipovska A, Polosa PL, Gustafsson CM, Larsson NG (2016) POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA. Sci Adv. 2016 Aug 5;2(8):e1600963

Le HQ, Ghatak S, Yeung CC, Tellkamp F, Günschmann C, Dieterich C, Yeroslaviz A, Habermann B, Pombo A, Niessen CM, Wickström SA (2016) 
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Bratic A, Clemente P, Calvo-Garrido J, Maffezzini C, Felser A, Wibom R, Wedell A, Freyer C, Wredenberg A (2016) Mitochondrial Polyadenylation Is a One-Step Process Required for mRNA Integrity and tRNA Maturation. PLoS Genet. 2016 May 13;12(5):e1006028

Nakamura S, Karalay Ö, Jäger PS, Horikawa M, Klein C, Nakamura K, Latza C, Templer SE, Dieterich C, Antebi A (2016) Mondo complexes regulate TFEB via TOR inhibition to promote longevity in response to gonadal signals. Nat Commun 7:10944

Velázquez AP, Tatsuta T, Ghillebert R, Drescher I, Graef M (2016) Lipid droplet-mediated ER homeostasis regulates autophagy and cell survival during starvation. J Cell Biol 212(6):621-31

Morgner J, Ghatak S, Jakobi T, Dieterich C, Aumailley M, Wickström SA (2015) Integrin-linked kinase regulates the niche of quiescent epidermal stem cells. Nat Commun 6:8198

Mourier A, Motori E, Brandt T, Lagouge M, Atanassov I, Galinier A, Rappl G, Brodesser S, Hultenby K, Dieterich C, Larsson NG (2015) Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels. J Cell Biol 208, 429-442