Dr. Hannah Scheiblich (she/her)

CV

Scientific Career

2024 - heute    |    Max Planck Research Group Leader
Max Planck Institute for Biology of Ageing, Cologne, Germany
2023 - 2024    |    Junior Research Group Leader
Medical Faculty, Rheinische Friedrich-Wilhelm University Bonn, Germany
2016 - 2023    |    Postdoctoral fellow with Prof. Michael T. Heneka
Medical Faculty, Rheinische Friedrich-Wilhelm University Bonn, Germany
2016 - 2016    |    Postdoctoral fellow with Dr. Joern Steinert
Medical Research Council (MRC), University of Leicester, England

Education

2012 - 2015    |    Dr. rer. nat.
University of Veterinary Medicine Hannover, Germany
2009 - 2011    |    Master of Science (MSc)
University of Veterinary Medicine Hannover, Germany
2006 - 2009    |    Bachelor of Science (BSc)
Philipps University of Marburg, Germany

Third-party funding

2024 - 2027    |    Alzheimer Forschung Initiative
Role of intercellular neuron-microglia contacts in tauopathies    
2023                |    Cluster of Excellence ImmunoSensation    
Funding of junior research group      
2023                |    Cluster of Excellence ImmunoSensation
Postdoc Innovation Fund
2020 - 2023    |    Gemeinnützige Hertie Stiftung
Unravelling an “on demand” α-synuclein degradation strategy in microglia

Prizes / Awards

2023                |    Best Poster Prize
7th Venusberg Meeting in Neuroinflammation, Luxembourg
2022                |    3rd place winner of the “Best Paper Prize 2022”
verliehen durch die Hans & Ilse Breuer Stiftung und dem Deutsches Zentrum für Neurodegenerative Erkrankungen e. V. (DZNE)
2017                |    3rd place winner of the Mark A. Smith Prize, Journal of Neurochemistry
2016                |    Travel grant, German Neuroscience Society
2015                |    Young Research Scholarship, German Neuroscience Society

Selected Publications

Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes
Scheiblich H, Dansokho C, Mercan D, Schmidt SV, Bousset L, Wischhof L, Eikens F, Odainic A, Spitzer J, Griep A, Schwartz S, Bano D, Latz E, Melki R, Heneka MTH
(2021) Cell, doi: 10.1016/j.cell.2021.09.007

Microglial NLRP3 Inflammasome Activation upon TLR2 and TLR5 Ligation by Distinct α-Synuclein Assemblies
Scheiblich H, Bousset L, Schwartz S, Griep A, Latz E, Melki R, Heneka MTH
(2021) J Immunol, doi: 10.4049/jimmunol.2100035

β-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia
Friker LL, Scheiblich H, Hochheiser IV, Brinkschulte R, Riedel D, Latz E, Geyer M, Heneka MT
(2021) Cell Rep, doi: 10.1016/j.celrep.2020.02.025

NLRP3 inflammasome activation drives tau pathology
Ising C, Venegas C, Zhang S, Scheiblich H, Schmidt SV, Vieira-Saecker A, Schwartz S, Albasset S, McManus RM, Tejera D, Griep A, Santarelli F, Brosseron F, Opitz S, Stunden J, Merten M, Kayed R, Golenbock DT, Blum D, Latz E, Buée L, Heneka MT
(2019) Nature, doi: 10.1038/s41586-019-1769-z

Activation of the NLRP3 inflammasome in microglia: the role of ceramide
Scheiblich H, Schlütter A, Golenbock DT, Latz E, Martinez-Martinez P, Heneka MT
(2017) J Neurochem, doi: 10.1111/jnc.14225

Full publication list; see https://www.age.mpg.de/382088/publications