Publications of H. Nolte

Eiyama, A.; Aaltonen, M. J.; Nolte, H.; Tatsuta, T.; Langer, T.: Disturbed intramitochondrial phosphatidic acid transport impairs cellular stress signaling. J Biol Chem 296, p. 100335 (2021)

Sprenger, H.-G.; MacVicar, T.; Bahat, A.; Fiedler, K. U.; Hermans, S.; Ehrentraut, D.; Ried, K.; Milenkovic, D.; Bonekamp, N.; Larsson, N.G. et al.; Nolte, H.; Giavalisco, P.; Langer, T.: Cellular pyrimidine imbalance triggers mitochondrial DNA–dependent innate immunity. Nature Metabolism 3 (5), pp. 636 - 650 (2021)

Mittenbühler, M. J.; Saedler, K.; Nolte, H.; Kern, L.; Zhou, J.; Qian, S. B.; Meder, L.; Ullrich, R. T.; Brüning, J. C.; Wunderlich, F. T.: Hepatic FTO is dispensable for the regulation of metabolism but counteracts HCC development in vivo. Mol Metab 42, p. 101085 (2020)

MacVicar, T.; Ohba, Y.; Nolte, H.; Mayer, F. C.; Tatsuta, T.; Sprenger, H.-G.; Lindner, B.; Zhao, Y.; Li, J.; Bruns, C. et al.; Kruger, M.; Habich, M.; Riemer, J.; Schwarzer, R.; Pasparakis, M.; Henschke, S.; Bruning, J. C.; Zamboni, N.; Langer, T.: Lipid signalling drives proteolytic rewiring of mitochondria by YME1L. Nature 575 (7782), pp. 361 - 365 (2019)

Hammerschmidt, P.; Ostkotte, D.; Nolte, H.; Gerl, M. J.; Jais, A.; Brunner, H. L.; Sprenger, H.-G.; Awazawa, M.; Nicholls, H. T.; Turpin-Nolan, S. M. et al.; Langer, T.; Kruger, M.; Brugger, B.; Bruning, J. C.: CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity. Cell 177 (6), pp. 1536 - 1552 e23 (2019)

Brandt, C.; Nolte, H.; Henschke, S.; Engström Ruud, L.; Awazawa, M.; Morgan, D. A.; Gabel, P.; Sprenger, H.-G.; Hess, M. E.; Günther, S. et al.; Langer, T.; Rahmouni, K.; Fenselau, H.; Krüger, M.; Brüning, J. C.: Food Perception Primes Hepatic ER Homeostasis via Melanocortin-Dependent Control of mTOR Activation. Cell 175, pp. 1321 - 1335.e20 (2018)

Saita, S.; Nolte, H.; Fiedler, K. U.; Kashkar, H.; Venne, A. S.; Zahedi, R. P.; Kruger, M.; Langer, T.: PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis. Nat Cell Biol 19 (4), pp. 318 - 328 (2017)

Vukotic, M.; Nolte, H.; König, T.; Saita , S.; Ananjew, M.; Krüger, M.; Tatsuta, T.; Langer, T.: Acylglycerol Kinase Mutated in Sengers Syndrome Is a Subunit of the TIM22 Protein Translocase in Mitochondria. Molecular Cell 67, pp. 471 - 483.e7 (2017)

Wai, T.; Saita, S.; Nolte, H.; Muller, S.; Konig, T.; Richter-Dennerlein, R.; Sprenger, H.-G.; Madrenas, J.; Muhlmeister, M.; Brandt, U. et al.; Kruger, M.; Langer, T.: The membrane scaffold SLP2 anchors a proteolytic hub in mitochondria containing PARL and the i-AAA protease YME1L. EMBO Rep 17 (12), pp. 1844 - 1856 (2016)