Department Antebi

Molecular Genetics of Ageing

Ageing is defined as a gradual decline of organismal homeostasis and of physiologic functions throughout the body, and is associated with an increased risk of age-related disease. The Antebi Lab studies the regulatory mechanisms that govern these processes using the nematode worm C. elegans, the African turquoise killifish Nothobranchius furzeri and human cells. Our work brings together traditional genetic approaches with systems biology (transcriptomics, proteomics, interactomics and imaging) and state-of-the-art metabolomic and lipidomic profiling of ageing-related processes.| more |

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Contact

Personal Assistant

Michelle König

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Contact

Scientific Coordinator

Dr. Orsolya Symmons

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Third-party funding

  • 2020-2025 | ERC Advanced Grant
    NuAge, Nucleolar regulation of longevity
     
  • 2018-2025 | DFG/CECAD Cluster of Excellence Cellular Stress Responses in ageing-associated disease
     
  • 2018-2020 | Max Planck Society
    Lead development of small molecule activators of GFAT-1, in collaboration with Lead Discovery Center, Dortmund
     
  • 2018-2019 | DAAD
    Decoding Aging Initiative, in collaboration with Mori lab, Univ Campinas, Brazil
     
  • 2015-2020 | BMBF/EndoProtect:
    Prevention of neuronal protein aggregation through endogenous mechanisms
     
  • 2011-2015 | DFG, SFB 635: Posttranslational control of protein function
    Project C9: Regulation of C. elegans Developmental Timing by the F-box Protein  DRE-1/FBXO11
     
  • 2008-present | Max Planck Society Excellence Core Funding
    Toxic Protein Consortium

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