Department Antebi

Molecular Genetics of Ageing

Ageing is defined as a gradual decline of organismal homeostasis and of physiologic functions throughout the body, and is associated with an increased risk of age-related disease. The Antebi Lab studies the regulatory mechanisms that govern these processes using the nematode worm C. elegans, the African turquoise killifish Nothobranchius furzeri and human cells. Our work brings together traditional genetic approaches with systems biology (transcriptomics, proteomics, interactomics and imaging) and state-of-the-art metabolomic and lipidomic profiling of ageing-related processes.| more |

Contact

Personal Assistant

Michelle König

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Scientific Coordinator

Dr. Orsolya Symmons

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Third-party funding

  • 2019-2024 | European Research Council (ERC) H2020, Advanced Grant
    NUAGE: Nuclear regulation of longevity

  • 2015-2018 | BMBF EndoProtect
    Prevention of neuronal protein aggregation through endogenous mechanisms

  • 2011-2017 | DFG
    CECAD: EXC 229 - to support collaborative research in metabolism and longevity

  • 2011-2016 | BMBF
    GERONTOSYS - Forschungskern: SyBACol (Systems Biology of Ageing Cologne); Project Area A: Systems Biology of Longevity Pathways; Subproject B

  • 2011-2015 | DFG
    SFB 635: Posttranslational control of protein function, Project C9: Regulation of C. elegans Developmental Timing by the F-box Protein  DRE-1/FBXO11

  • 2011-2014  | Max Planck Excellence Funds
    Toxic Protein Consortium

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