Publications

Timofeev, O.; Giron, P.; Lawo, S.; Pichler, M.; Noeparast, M.: ERK pathway agonism for cancer therapy: evidence, insights, and a target discovery framework. npj Precision Oncology 8, 70 (2024)

Rivera Mejias, P.; Narbona-Pérez, Á. J.; Hasberg, L.; Kroczek, L.; Bahat, A.; Lawo, S.; Folz-Donahue, K.; Schumacher, A. L.; Ahola, S.; Mayer, F. C. et al.; Giavalisco, P.; Nolte, H.; Lavandero, S.; Langer, T.: The mitochondrial protease OMA1 acts as a metabolic safeguard upon nuclear DNA damage. Cell Reports 42, 112332, p. 112332 (2023)

Blanck, M.; Budnik-Zawilska, M. B.; Lenger, S. R.; McGonigle, J. E.; Martin, G. R. A.; le Sage, C.; Lawo, S.; Pemberton, H. N.; Tiwana, G. S.; Sorrell, D. A. et al.; Cross, B. C. S.: A Flexible, Pooled CRISPR Library for Drug Development Screens. Crispr j 3 (3), pp. 211 - 222 (2020)

le Sage, C.; Lawo, S.; Cross, B. C. S.: CRISPR: A Screener's Guide. SLAS Discov 25 (3), pp. 233 - 240 (2019)

le Sage, C.; Lawo, S.; Panicker, P.; Scales, T. M. E.; Rahman, S. A.; Little, A. S.; McCarthy, N. J.; Moore, J. D.; Cross, B. C. S.: Dual direction CRISPR transcriptional regulation screening uncovers gene networks driving drug resistance. Sci Rep 7 (1), p. 17693 (2017)

Cross, B. C.; Lawo, S.; Archer, C. R.; Hunt, J. R.; Yarker, J. L.; Riccombeni, A.; Little, A. S.; McCarthy, N. J.; Moore, J. D.: Increasing the performance of pooled CRISPR-Cas9 drop-out screening. Sci Rep 6, p. 31782 (2016)

Vizeacoumar, F. J.; Arnold, R.; Vizeacoumar, F. S.; Chandrashekhar, M.; Buzina, A.; Young, J. T.; Kwan, J. H.; Sayad, A.; Mero, P.; Lawo, S. et al.; Tanaka, H.; Brown, K. R.; Baryshnikova, A.; Mak, A. B.; Fedyshyn, Y.; Wang, Y.; Brito, G. C.; Kasimer, D.; Makhnevych, T.; Ketela, T.; Datti, A.; Babu, M.; Emili, A.; Pelletier, L.; Wrana, J.; Wainberg, Z.; Kim, P. M.; Rottapel, R.; O'Brien, C. A.; Andrews, B.; Boone, C.; Moffat, J.: A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities. Mol Syst Biol 9, p. 696 (2013)

Comartin, D.; Gupta, G. D.; Fussner, E.; Coyaud, E.; Hasegan, M.; Archinti, M.; Cheung, S. W.; Pinchev, D.; Lawo, S.; Raught, B. et al.; Bazett-Jones, D. P.; Luders, J.; Pelletier, L.: CEP120 and SPICE1 cooperate with CPAP in centriole elongation. Curr Biol 23 (14), pp. 1360 - 6 (2013)

Lawo, S.; Hasegan, M.; Gupta, G. D.; Pelletier, L.: Subdiffraction imaging of centrosomes reveals higher-order organizational features of pericentriolar material. Nat Cell Biol 14 (11), pp. 1148 - 58 (2012)

Hutchins, J. R.; Toyoda, Y.; Hegemann, B.; Poser, I.; Heriche, J. K.; Sykora, M. M.; Augsburg, M.; Hudecz, O.; Buschhorn, B. A.; Bulkescher, J. et al.; Conrad, C.; Comartin, D.; Schleiffer, A.; Sarov, M.; Pozniakovsky, A.; Slabicki, M. M.; Schloissnig, S.; Steinmacher, I.; Leuschner, M.; Ssykor, A.; Lawo, S.; Pelletier, L.; Stark, H.; Nasmyth, K.; Ellenberg, J.; Durbin, R.; Buchholz, F.; Mechtler, K.; Hyman, A. A.; Peters, J. M.: Systematic analysis of human protein complexes identifies chromosome segregation proteins. Science 328 (5978), pp. 593 - 9 (2010)

Lawo, S.; Bashkurov, M.; Mullin, M.; Ferreria, M. G.; Kittler, R.; Habermann, B.; Tagliaferro, A.; Poser, I.; Hutchins, J. R.; Hegemann, B. et al.; Pinchev, D.; Buchholz, F.; Peters, J. M.; Hyman, A. A.; Gingras, A. C.; Pelletier, L.: HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity. Curr Biol 19 (10), pp. 816 - 26 (2009)

Zhu, F.; Lawo, S.; Bird, A.; Pinchev, D.; Ralph, A.; Richter, C.; Muller-Reichert, T.; Kittler, R.; Hyman, A. A.; Pelletier, L.: The mammalian SPD-2 ortholog Cep192 regulates centrosome biogenesis. Curr Biol 18 (2), pp. 136 - 41 (2008)

Kittler, R.; Pelletier, L.; Heninger, A. K.; Slabicki, M.; Theis, M.; Miroslaw, L.; Poser, I.; Lawo, S.; Grabner, H.; Kozak, K. et al.; Wagner, J.; Surendranath, V.; Richter, C.; Bowen, W.; Jackson, A. L.; Habermann, B.; Hyman, A. A.; Buchholz, F.: Genome-scale RNAi profiling of cell division in human tissue culture cells. Nat Cell Biol 9 (12), pp. 1401 - 12 (2007)

Gawlinski, P.; Nikolay, R.; Goursot, C.; Lawo, S.; Chaurasia, B.; Herz, H. M.; Kussler-Schneider, Y.; Ruppert, T.; Mayer, M.; Grosshans, J.: The Drosophila mitotic inhibitor Fruhstart specifically binds to the hydrophobic patch of cyclins. EMBO Rep 8 (5), pp. 490 - 6 (2007)