Publications

Koletsou, E.; Huppertz, I.: RNA-binding proteins as versatile metabolic regulators. npj Metabolic Health and Disease 3, 1 (2025)

Huppertz, I.; Mullen, A. C.: Function Over Form: Defining Evolutionarily Conserved Long-noncoding RNAs Regulating Hepatic Metabolism. Gastroenterology (2025)

Huppertz, I.: Free ribosomal proteins as culprits for nucleolar stress. Molecular Cell 84, pp. 1400 - 1402 (2024)

Perez-Perri, J. I.; Ferring-Appel, D.; Huppertz, I.; Schwarzl, T.; Sahadevan, S.; Stein, F.; Rettel, M.; Galy, B.; Hentze, M. W.: The RNA-binding protein landscapes differ between mammalian organs and cultured cells. Nature Communications 14, 2074 (2023)

Huppertz, I.; Perez-Perri, J. I.; Mantas, P.; Sekaran, T.; Schwarzl, T.; Russo, F.; Ferring-Appel, D.; Koskova, Z.; Dimitrova-Paternoga, L.; Kafkia, E. et al.; Hennig, J.; Neveu, P. A.; Patil, K.; Hentze, M. W.: Riboregulation of Enolase 1 activity controls glycolysis and embryonic stem cell differentiation. Mol Cell 82 (14), pp. 2666 - 2680 e11 (2022)

Buscher, M.; Horos, R.; Huppertz, I.; Haubrich, K.; Dobrev, N.; Baudin, F.; Hennig, J.; Hentze, M. W.: Vault RNA1-1 riboregulates the autophagic function of p62 by binding to lysine 7 and arginine 21, both of which are critical for p62 oligomerization. RNA 28 (5), pp. 742 - 755 (2022)

Hallegger, M.; Chakrabarti, A. M.; Lee, F. C.Y.; Lee, B. L.; Amalietti, A. G.; Odeh, H. M.; Copley, K. E.; Rubien, J. D.; Portz, B.; Kuret, K. et al.; Huppertz, I.; Rau, F.; Patani, R.; Fawzi, N. L.; Shorter, J.; Luscombe, N. M.; Ule, J.: TDP-43 condensation properties specify its RNA-binding and regulatory repertoire. Cell 184, pp. 4680 - 4696.e22 (2021)

Cooke, A.; Schwarzl, T.; Huppertz, I.; Kramer, G.; Mantas, P.; Alleaume, A.-M.; Huber, W.; Krijgsveld, J.; Hentze, M. W.: The RNA-Binding Protein YBX3 Controls Amino Acid Levels by Regulating SLC mRNA Abundance. Cell Reports 27, pp. 3097 - 3106.e5 (2019)

Huppertz, I.; Haberman, N.; Ule, J.: 'Read-through marking' reveals differential nucleotide composition of read-through and truncated cDNAs in iCLIP. Wellcome Open Res 3, p. 77 (2018)

Haberman, N.; Huppertz, I.; Attig, J.; Konig, J.; Wang, Z.; Hauer, C.; Hentze, M. W.; Kulozik, A. E.; Le Hir, H.; Curk, T. et al.; Sibley, C. R.; Zarnack, K.; Ule, J.: Insights into the design and interpretation of iCLIP experiments. Genome Biol 18 (1), p. 7 (2017)

Rot, G.; Wang, Z.; Huppertz, I.; Modic, M.; Lence, T.; Hallegger, M.; Haberman, N.; Curk, T.; von Mering, C.; Ule, J.: High-resolution RNA maps suggest common principles of splicing and polyadenylation regulation by TDP-43. Cell Rep 19 (5), pp. 1056 - 1067 (2017)

Chan, S. L.; Huppertz, I.; Yao, C.; Weng, L.; Moresco, J. J.; Yates, J. R.,. 3.; Ule, J.; Manley, J. L.; Shi, Y.: CPSF30 and Wdr33 directly bind to AAUAAA in mammalian mRNA 3' processing. Genes Dev 28 (21), pp. 2370 - 80 (2014)

Huppertz, I.; Attig, J.; D'Ambrogio, A.; Easton, L. E.; Sibley, C. R.; Sugimoto, Y.; Tajnik, M.; Konig, J.; Ule, J.: iCLIP: protein-RNA interactions at nucleotide resolution. Methods 65 (3), pp. 274 - 87 (2013)