Publications

Medeiros, T. C.; Ovciarikova, J.; Li, X.; Krüger, P.; Bartsch, T.; Reato, S.; Crow, J. C.; Tellez Sutterlin, M.; Martins Garcia, B.; Rais, I. et al.; Allmeroth, K.; Hartman, M. D.; Denzel, M.; Purrio, M.; Mesaros, A.; Leung, K.-Y.; Greene, N. D. E.; Sheiner, L.; Giavalisco, P.; Pernas, L.: Mitochondria protect against an intracellular pathogen by restricting access to folate. Science 389 (2025)

Martins Garcia, B.; Philipp, M.; Medeiros, T. C.; Hendrix, S.; Prabhu , K.; Corrado, M.; Kingma, J.; Gorbatenko, A.; Deshwal, S.; Veronese, M. et al.; Scorrano, L.; Pearce, E.; Giavalisco, P.; Zelcer, N.; Pernas, L.: Glutamine sensing licenses cholesterol synthesis. The EMBO Journal (2024)

Kreimendahl, S.; Pernas, L.: Metabolic immunity against microbes. Trends in Cell Biology 34, pp. 496 - 508 (2024)

Mehra, C.; Pernas, L.: Contact sites between host organelles and pathogens: boon or bane? mSphere (2023)

Martins Garcia, B.: Don’t face writer’s block alone. eLife 12 (2023)

Beros, S.; Pernas, L.: Sleeping monsters: chronic infections in COVID-19 pathogenesis. Trends in Microbiology (2023)

Kreimendahl, S.; Pernas, L.: Metabolic immunity against microbes. Trends in Cell Biology (2023)

Philipp, M.; Garcia, B. M.: Mitochondria are midfield players in steroid synthesis. The International Journal of Biochemistry & Cell Biology 160, 106431, p. 106431 (2023)

Li, W.; Grech, J.; Stortz, J. F.; Gow, M.; Periz, J.; Meissner, M.; Jimenez-Ruiz, E.: A splitCas9 phenotypic screen in Toxoplasma gondii identifies proteins involved in host cell egress and invasion. Nat Microbiol (2022)

Li, X.; Straub, J.; Medeiros, T. C.; Mehra, C.; den Brave, F.; Peker, E.; Atanassov, I.; Stillger, K.; Michaelis, J. B.; Burbridge, E. et al.; Adrain, C.; Munch, C.; Riemer, J.; Becker, T.; Pernas, L.: Mitochondria shed their outer membrane in response to infection-induced stress. Science 375 (6577), p. eabi4343 (2022)

Medeiros, T. C.; Mehra, C.; Pernas, L.: Contact and competition between mitochondria and microbes. Curr Opin Microbiol 63, pp. 189 - 194 (2021)

Mehra, C.; Pernas, L.: Move it to lose it: Mitocytosis expels damaged mitochondria. Dev Cell 56 (14), pp. 2014 - 2015 (2021)

Pernas, L.: Cellular metabolism in the defense against microbes. J Cell Sci 134 (5) (2021)

Carvalho, K. F.; Machado, T. S.; Garcia, B. M.; Zangirolamo, A. F.; Macabelli, C. H.; Sugiyama, F. H. C.; Grejo, M. P.; Augusto Neto, J. D.; Tostes, K.; Ribeiro, F. K. S. et al.; Sarapiao, F. D.; Pandey, A. K.; Nociti, R. P.; Tizioto, P.; Coutinho, L. L.; Meirelles, F. V.; Guimaraes, F. E. G.; Pernas, L.; Seneda, M. M.; Chiaratti, M. R.: Mitofusin 1 is required for oocyte growth and communication with follicular somatic cells. FASEB J 34 (6), pp. 7644 - 7660 (2020)

Pernas, L.: mSphere of Influence: Finding a Direction-How Do Mitochondria Know Where To Go? mSphere 4 (4) (2019)

Pernas, L.; Bean, C.; Boothroyd, J. C.; Scorrano, L.: Mitochondria Restrict Growth of the Intracellular Parasite Toxoplasma gondii by Limiting Its Uptake of Fatty Acids. Cell Metab 27 (4), pp. 886 - 897 e4 (2018)

Blank, M. L.; Parker, M. L.; Ramaswamy, R.; Powell, C. J.; English, E. D.; Adomako-Ankomah, Y.; Pernas, L. F.; Workman, S. D.; Boothroyd, J. C.; Boulanger, M. J. et al.; Boyle, J. P.: A Toxoplasma gondii locus required for the direct manipulation of host mitochondria has maintained multiple ancestral functions. Mol Microbiol 108 (5), pp. 519 - 535 (2018)

Pernas, L. F.; Scorrano, L.: RevAMPing Mitochondrial Shape to Live Longer. Cell Metab 26 (6), pp. 805 - 806 (2017)

Adomako-Ankomah, Y.; English, E. D.; Danielson, J. J.; Pernas, L.; Parker, M. L.; Boulanger, M. J.; Dubey, J. P.; Boyle, J. P.: Host Mitochondrial Association Evolved in the Human Parasite Toxoplasma gondii via Neofunctionalization of a Gene Duplicate. Genetics 203 (1), pp. 283 - 98 (2016)

Pernas, L.; Scorrano, L.: Mito-Morphosis: Mitochondrial Fusion, Fission, and Cristae Remodeling as Key Mediators of Cellular Function. Annu Rev Physiol 78, pp. 505 - 31 (2016)