Dr. Ron Jachimowicz (he/him)

CV

Scientific Career

2021 - today    |    Attending Physician
Clinic I of Internal Medicine, Department of Hematology, Oncology and Infectious Diseases, University Hospital Cologne, Germany
2020 - today    |    Max Planck Research Group Leader
Max Planck Institute for Biology of Ageing, Cologne, Germany
2017 - 2021    |    Resident Physician
Clinic I of Internal Medicine, Department of Hematology, Oncology and Infectious Diseases, University Hospital Cologne, Germany
2017 - 2020    |    Postdoctoral Fellow
CECAD Research Center, University of Cologne, with Prof. Christian Reinhardt, Germany
2014 - 2017    |    Postdoctoral Fellow
The David and Inez Myers Laboratory of Cancer Genetics, Sackler School of Medicine, University of Tel Aviv, with Dr. Yosef Shiloh, Israel
2013 - 2014    |    Postdoctoral Fellow
CECAD Research Center, University of Cologne, with Prof. Christian Reinhardt, Germany
2010 - 2014    |    Resident Physician
Clinic I of Internal Medicine, Department of Hematology, Oncology and Infectious Diseases, University Hospital Cologne, Germany

Education

2003 - 2010    |    Medical School, Medical Faculty
University of Cologne
2007 - 2010    |    MD thesis, Medical Faculty
University of Cologne, with Prof. Elke Pogge von Strandmann and Prof. Andreas Engert

Prizes/Awards

2021    |    Faculty Award for the best individual publication
Faculty of Medicine, University of Cologne
2020    |    Theodor-Frerichs-Award
German Society for Internal Medicine (DGIM)

Third-party funding

2023 - 2024    |    Else Kröner Fresenius Research College Fellowship to Dr. Moritz Gräf
2023 -2025     |    Behrens-Weise Stiftung Grant - improving and maintaining human health
2023 - 2026    |    Research Unit FOR5504 Grant, German Research Foundation
2022 - 2026    |    Research Network CANTAR Grant
Cancer Targeting, Ministry of Culture and Science of the State of North Rhine-Westphalia (MKW NRW)
2021 - 2023    |    Mildred Scheel School of Oncology Fellowship to Dr. Paul Bröckelmann
2021 - 2023    |    Paul Fentener van Vlissingen Fellowship to Dr. Mathilde de Jong
2020 - 2022    |    Mildred Scheel School of Oncology Fellowship to Dr. Orsolya Leidecker
2020 - 2024    |   Else Kröner Research College: Clonal Evolution in Cancer Grant

Selected Publications

UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors
Jachimowicz, R. D., Beleggia, F., Isensee, J., Velpula, B. B., Goergens, J., Bustos, M. A., Doll, M. A., Shenoy, A., Checa-Rodriguez, C., Wiederstein, J. L., Baranes-Bachar, K., Bartenhagen, C., Hertwig, F., Teper, N., Nishi, T., Schmitt, A., Distelmaier, F., Ludecke, H. J., Albrecht, B., Kruger, M., Schumacher, B., Geiger, T., Hoon, D. S. B., Huertas, P., Fischer, M., Hucho, T., Peifer, M., Ziv, Y., Reinhardt, H. C., Wieczorek, D., Shiloh, Y.
(2019) Cell, 176, 3, 505-519 e22

DNA double-strand break repair pathway choice - from basic biology to clinical exploitation
Jachimowicz, R. D., Goergens, J., Reinhardt, H. C.
(2019) Cell Cycle, 18, 13, 1423-1434

Genomic Amplification of UBQLN4 Is a Prognostic and Treatment Resistance Factor
Kobayashi Y., Bustos M. A. , Shoji Y., Jachimowicz R.D., Shiloh Y., Hoon D.S.B.
Cells. 2022 Oct 21;11(20):3311. doi: 10.3390/cells11203311.

ATM activity in T cells is critical for immune surveillance of lymphoma in vivo
Riabinska, A., Lehrmann, D., Jachimowicz, R. D., Knittel, G., Fritz, C., Schmitt, A., Geyer, A., Heneweer, C., Wittersheim, M., Frenzel, L. P., Torgovnick, A., Wiederstein, J. L., Wunderlich, C. M., Ortmann, M., Paillard, A., Wossmann, W., Borkhardt, A., Burdach, S., Hansmann, M. L., Rosenwald, A., Perner, S., Mall, G., Klapper, W., Merseburg, A., Kruger, M., Grull, H., Persigehl, T., Wunderlich, F. T., Peifer, M., Utermohlen, O., Buttner, R., Beleggia, F., Reinhardt, H. C.
(2020) Leukemia, 34, 3, 771-786

Distinct Genetically Determined Origins of Myd88/BCL2-Driven Aggressive Lymphoma Rationalize Targeted Therapeutic Intervention Strategies
Flümann R., Hansen J., Pelzer B.W., Nieper P., Lohmann T., Kisis I., Riet T.,  Kohlhas V., Nguyen P.H., Peifer M., Abedpour N., Bosco G., Thomas R.K., Kochanek M., Knüfer J., Jonigkeit L., Beleggia F.,  Holzem A., Büttner R., Lohneis P., Meinel J., Ortmann M., Persigehl T., Hallek M., Calado D.P., Chmielewski M., Klein S., Göthert J.R., Chapuy B., Zevnik B., Wunderlich F.T., Tresckow B.v.,  Jachimowicz R.D.,  Melnick A.M., Reinhardt H.C., Knittel G.
Blood Cancer Discov. 2022 Nov 8:BCD- 22-0007. doi: 10.1158/2643-3230.BCD-22-0007.

For full publication list; see https://www.age.mpg.de/jachimowicz/publications