Publications of N.G. Larsson

Bonekamp, N.; Larsson, N.G.: SnapShot: Mitochondrial Nucleoid. Cell 172 (1-2), pp. 388 - 388 e1 (2018)

Nicholls, T. J.; Nadalutti, C. A.; Motori, E.; Sommerville, E. W.; Gorman, G. S.; Basu, S.; Hoberg, E.; Turnbull, D. M.; Chinnery, P. F.; Larsson, N.G. et al.; Larsson, E.; Falkenberg, M.; Taylor, R. W.; Griffith, J. D.; Gustafsson, C. M.: Topoisomerase 3alpha Is Required for Decatenation and Segregation of Human mtDNA. Mol Cell 69 (1), pp. 9 - 23 e6 (2018)

Kauppila, J. H. K.; Bonekamp, N.; Mourier, A.; Isokallio, M.; Just, A.; Kauppila, T.; Stewart, J.; Larsson, N.G.: Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice. Nucleic Acids Res 46 (13), pp. 6642 - 6669 (2018)

Matic, S.; Jiang, M.; Nicholls, T. J.; Uhler, J. P.; Dirksen-Schwanenland, C.; Polosa, P. L.; Simard, M.-L.; Li, X.; Atanassov, I.; Rackham, O. et al.; Filipovska, A.; Stewart, J.; Falkenberg, M.; Larsson, N.G.; Milenkovic, D.: Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria. Nat Commun 9 (1), p. 1202 (2018)

Siira, S. J.; Spahr, H.; Shearwood, A. J.; Ruzzenente, B.; Larsson, N.G.; Rackham, O.; Filipovska, A.: LRPPRC-mediated folding of the mitochondrial transcriptome. Nat Commun 8 (1), p. 1532 (2017)

Kühl, I.; Miranda, M.; Atanassov, I.; Kuznetsova, I.; Hinze, Y.; Mourier, A.; Filipovska, A.; Larsson, N.G.: Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals. Elife 6 (2017)

Brandt, T.; Mourier, A.; Tain, L. S.; Partridge, L.; Larsson, N.G.; Kuhlbrandt, W.: Changes of mitochondrial ultrastructure and function during ageing in mice and Drosophila. Elife 6 (2017)

Milenkovic, D.; Blaza, J. N.; Larsson, N.G.; Hirst, J.: The Enigma of the Respiratory Chain Supercomplex. Cell Metab 25 (4), pp. 765 - 776 (2017)

Kauppila, J. H. K.; Baines, H. L.; Bratic, A.; Simard, M.-L.; Freyer, C.; Mourier, A.; Stamp, C.; Filograna, R.; Larsson, N.G.; Greaves, L. C. et al.; Stewart, J. B.: A Phenotype-Driven Approach to Generate Mouse Models with Pathogenic mtDNA Mutations Causing Mitochondrial Disease. Cell Rep 16 (11), pp. 2980 - 90 (2016)

Perez-Perez, R.; Lobo-Jarne, T.; Milenkovic, D.; Mourier, A.; Bratic, A.; Garcia-Bartolome, A.; Fernandez-Vizarra, E.; Cadenas, S.; Delmiro, A.; Garcia-Consuegra, I. et al.; Arenas, J.; Martin, M. A.; Larsson, N.G.; Ugalde, C.: COX7A2L Is a Mitochondrial Complex III Binding Protein that Stabilizes the III2+IV Supercomplex without Affecting Respirasome Formation. Cell Rep 16 (9), pp. 2387 - 98 (2016)

Kühl, I.; Miranda, M.; Posse, V.; Milenkovic, D.; Mourier, A.; Siira, S. J.; Bonekamp, N.; Neumann, U.; Filipovska, A.; Polosa, P. L. et al.; Gustafsson, C. M.; Larsson, N.G.: POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA. Sci Adv 2 (8), p. e1600963 (2016)

Rackham, O.; Busch, J. D.; Matic, S.; Siira, S. J.; Kuznetsova, I.; Atanassov, I.; Ermer, J. A.; Shearwood, A. M.; Richman, T. R.; Stewart, J. B. et al.; Mourier, A.; Milenkovic, D.; Larsson, N.G.; Filipovska, A.: Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly. Cell Rep 16 (7), pp. 1874 - 90 (2016)

Richman, T. R.; Spahr, H.; Ermer, J. A.; Davies, S. M.; Viola, H. M.; Bates, K. A.; Papadimitriou, J.; Hool, L. C.; Rodger, J.; Larsson, N.G. et al.; Rackham, O.; Filipovska, A.: Loss of the RNA-binding protein TACO1 causes late-onset mitochondrial dysfunction in mice. Nat Commun 7, p. 11884 (2016)

Ramos, E.S.; Larsson, N.G.; Mourier, A.: Bioenergetic roles of mitochondrial fusion. Biochim Biophys Acta 1857 (8), pp. 1277 - 83 (2016)

Gustafsson, C. M.; Falkenberg, M.; Larsson, N.G.: Maintenance and Expression of Mammalian Mitochondrial DNA. Annu Rev Biochem 85, pp. 133 - 60 (2016)

Gustafsson, C. M.; Falkenberg, M.; Larsson, N.G.: Maintenance and Expression of Mammalian Mitochondrial DNA. Annual review of biochemistry 85, pp. 133 - 160 (2016)

Kauppila, J. H. K.; Baines, H. L.; Bratic, A.; Simard, M.-L.; Freyer, C.; Mourier, A.; Stamp, C.; Filograna, R.; Larsson, N.G.; Greaves, L. C. et al.; Stewart, J. B.: A Phenotype-Driven Approach to Generate Mouse Models with Pathogenic mtDNA Mutations Causing Mitochondrial Disease. Cell reports 16 (11), pp. 2980 - 2990 (2016)

Kühl, I.; Miranda, M.; Posse, V.; Milenkovic, D.; Mourier, A.; Siira, S. J.; Bonekamp, N. A.; Neumann, U.; Filipovska, A.; Polosa, P. L. et al.; Gustafsson, C. M.; Larsson, N.G.: POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA. Science advances 2 (8), p. e1600963 (2016)

Rackham, O.; Busch, J. D.; Matic, S.; Siira, S. .; Kuznetsova, I.; Atanassov, I.; Ermer, J. .; Shearwood, A.-M. J.; Richman, T. .; Stewart, J. B. et al.; Mourier, A.; Milenkovic, D.; Larsson, N.G.; Filipovska, A.: Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly. Cell Reports 16 (7), pp. 1874 - 1890 (2016)

Richman, T. R.; Spåhr, H.; Ermer, J. A.; Davies, S. M. K.; Viola, H. M.; Bates, K. A.; Papadimitriou, J.; Hool, L. C.; Rodger, J.; Larsson, N.G. et al.; Rackham, O.; Filipovska, A.: Loss of the RNA-binding protein TACO1 causes late-onset mitochondrial dysfunction in mice. Nature communications 7, p. 11884 (2016)