Publications of S. A. Fernandes

Fernandes, S. A.; Angelidaki, D.-D.; Nuechel, J.; Pan, J.; Gollwitzer, P.; Elkis, Y.; Artoni, F.; Wilhelm, S.; Kovacevic-Sarmiento, M.; Demetriades, C.: Spatial and functional separation of mTORC1 signalling in response to different amino acid sources. Nature Cell Biology (2024)

Nicastro , R.; Brohée, L.; Alba, J.; Nuechel, J.; Figlia, G.; Kipschull, S.; Gollwitzer, P.; Romero-Pozuelo, J.; Fernandes, S. A.; Lamprakis, A. et al.; Vanni, S.; Teleman, A. A.; De Virgilio, C.; Demetriades, C.: Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitor. Nature Cell Biology (2023)

Huang, W.; Kew, C.; Fernandes, S. A.; Löhrke, A.; Han , L.; Demetriades, C.; Antebi, A.: Decreased spliceosome fidelity and egl-8 intron retention inhibit mTORC1 signaling to promote longevity. Nature Aging 2 (9), pp. 796 - 808 (2022)

Nicastro , R.; Brohée, L.; Alba, J.; Nuechel, J.; Figlia, G.; Kipschull , S.; Gollwitzer, P.; Romero-Pozuelo, J.; Fernandes, S. A.; Lamprakis, A. et al.; Vanni, S.; Teleman, A. A.; De Virgilio, C.; Demetriades, C.: Malonyl-CoA is an ancient physiological ATP-competitive mTORC1 inhibitor. bioRxiv, p. 2022.11.06.515351 (2022)

Fernandes, S. A.; Demetriades, C.: The Multifaceted Role of Nutrient Sensing and mTORC1 Signaling in Physiology and Aging. Frontiers in Aging 2 (2021)