Publications of S. Grönke

Juricic, P.; Grönke, S.; Partridge, L.: Branched-Chain Amino Acids Have Equivalent Effects to Other Essential Amino Acids on Lifespan and Aging-Related Traits in Drosophila. J Gerontol A Biol Sci Med Sci 75 (1), pp. 24 - 31 (2019)

Weigelt, C. M.; Hahn, O.; Arlt, K.; Gruhn, M.; Jahn, A. J.; Esser, J.; Werner, J. A.; Klein, C.; Buschges, A.; Grönke, S. et al.; Partridge, L.: Loss of miR-210 leads to progressive retinal degeneration in Drosophila melanogaster. Life Sci Alliance 2 (1) (2019)

Hahn, O.; Stubbs, T. M.; Reik, W.; Grönke, S.; Beyer, A.; Partridge, L.: Hepatic gene body hypermethylation is a shared epigenetic signature of murine longevity. PLoS Genet 14 (11), p. e1007766 (2018)

Moens, T. G.; Mizielinska, S.; Niccoli, T.; Mitchell, J. S.; Thoeng, A.; Ridler, C. E.; Grönke, S.; Esser, J.; Heslegrave, A.; Zetterberg, H. et al.; Partridge, L.; Isaacs, A. M.: Sense and antisense RNA are not toxic in Drosophila models of C9orf72-associated ALS/FTD. Acta Neuropathol 135 (3), pp. 445 - 457 (2018)

Gorsky, M. K.; Burnouf, S.; Sofola-Adesakin, O.; Dols, J.; Augustin, H.; Weigelt, C. M.; Grönke, S.; Partridge, L.: Pseudo-acetylation of multiple sites on human Tau proteins alters Tau phosphorylation and microtubule binding, and ameliorates amyloid beta toxicity. Sci Rep 7 (1), p. 9984 (2017)

Hahn, O.; Grönke, S.; Stubbs, T. M.; Ficz, G.; Hendrich, O.; Krueger, F.; Andrews, S.; Zhang, Q.; Wakelam, M. J.; Beyer, A. et al.; Reik, W.; Partridge, L.: Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism. Genome Biol 18 (1), p. 56 (2017)

Tain, L. S.; Sehlke, R.; Jain, C.; Chokkalingam, M.; Nagaraj, N.; Essers, P.; Rassner, M.; Grönke, S.; Froelich, J.; Dieterich, C. et al.; Mann, M.; Alic, N.; Beyer, A.; Partridge, L.: A proteomic atlas of insulin signalling reveals tissue-specific mechanisms of longevity assurance. Mol Syst Biol 13 (9), p. 939 (2017)

Burnouf, S.; Grönke, S.; Augustin, H.; Dols, J.; Gorsky, M. K.; Werner, J. A.; Kerr, F.; Alic , N.; Martinez, P.; Partridge, L.: Deletion of endogenous Tau proteins is not detrimental in Drosophila. Scientific Reports 6, p. 23102 (2016)

Iyer, J.; Wang, Q.; Le, T.; Pizzo, L.; Grönke, S.; Ambegaokar, S. S.; Imai, Y.; Srivastava, A.; Troisi, B. L.; Mardon, G. et al.; Artero, R.; Jackson, G. R.; Isaacs, A. M.; Partridge, L.; Lu, B.; Kumar, J. P.; Girirajan, S.: Quantitative Assessment of Eye Phenotypes for Functional Genetic Studies Using Drosophila melanogaster. G3 (Bethesda) 6 (5), pp. 1427 - 37 (2016)

Kakanj, P.; Moussian, B.; Grönke, S.; Bustos, V.; Eming, S. A.; Partridge, L.; Leptin, M.: Insulin and TOR signal in parallel through FOXO and S6K to promote epithelial wound healing. Nat Commun 7, p. 12972 (2016)

Kinghorn, K. J.; Grönke, S.; Castillo-Quan, J. I.; Woodling, N. S.; Li, L.; Sirka, E.; Gegg, M.; Mills, K.; Hardy, J.; Bjedov, I. et al.; Partridge, L.: A Drosophila Model of Neuronopathic Gaucher Disease Demonstrates Lysosomal-Autophagic Defects and Altered mTOR Signalling and Is Functionally Rescued by Rapamycin. J Neurosci 36 (46), pp. 11654 - 11670 (2016)

Niccoli, T.; Cabecinha, M.; Tillmann, A.; Kerr, F.; Wong, C. T.; Cardenes, D.; Vincent, A. J.; Bettedi, L.; Li, L.; Grönke, S. et al.; Dols, J.; Partridge, L.: Increased Glucose Transport into Neurons Rescues Abeta Toxicity in Drosophila. Curr Biol 26 (17), pp. 2291 - 300 (2016)

Bratic, A.; Kauppila, T. E. S.; Macao , B.; Grönke, S.; Siibak, T.; Stewart, J. B.; Baggio, F.; Dols, J.; Partridge, L.; Falkenberg, M. et al.; Wredenberg, A.; Larsson, N.G.: Complementation between polymerase- and exonuclease-deficient mitochondrial DNA polymerase mutants in genomically engineered flies. Nat Commun 6, p. 8808 (2015)

Burnouf, S.; Gorsky, M. K.; Dols, J.; Grönke, S.; Partridge, L.: Abeta is neurotoxic and primes aggregation of Abeta in vivo. Acta Neuropathol (2015)

Metaxakis, A.; Tain, L. S.; Grönke, S.; Hendrich, O.; Hinze, Y.; Birras, U.; Partridge, L.: Lowered insulin signalling ameliorates age-related sleep fragmentation in Drosophila. PLoS Biol 12 (4), p. e1001824 (2014)

Mizielinska, S.; Grönke, S.; Niccoli, T.; Ridler, C. E.; Clayton, E. L.; Devoy, A.; Moens, T.; Norona, F. E.; Woollacott, I. O. C.; Pietrzyk, J. et al.; Cleverley, K.; Nicoll, A. J.; Pickering-Brown, S.; Dols, J.; Cabecinha, M.; Hendrich, O.; Fratta, P.; Fisher, E. M. C.; Partridge, L.; Isaacs, A. M.: C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins. Science 345 (6201), pp. 1192 - 1194 (2014)

Wredenberg, A.; Lagouge, M.; Bratic, A.; Metodiev, M. D.; Spahr, H.; Mourier, A.; Freyer, C.; Ruzzenente, B.; Tain, L. S.; Grönke, S. et al.; Baggio, F.; Kukat, C.; Kremmer, E.; Wibom, R.; Polosa, P. L.; Habermann, B.H.; Partridge, L.; Park, C. B.; Larsson, N.G.: MTERF3 regulates mitochondrial ribosome biogenesis in invertebrates and mammals. PLoS Genet 9 (1), p. e1003178 (2013)

Bratic, A.; Wredenberg, A.; Grönke, S.; Stewart, J. B.; Mourier, A.; Ruzzenente, B.; Kukat, C.; Wibom, R.; Habermann, B.H.; Partridge, L. et al.; Larsson, N.G.: The bicoid stability factor controls polyadenylation and expression of specific mitochondrial mRNAs in Drosophila melanogaster. PLoS Genet 7 (10), p. e1002324 (2011)

Wigby, S.; Slack, C.; Grönke, S.; Martinez, P.; Calboli, F. C.; Chapman, T.; Partridge, L.: Insulin signalling regulates remating in female Drosophila. Proc Biol Sci 278 (1704), pp. 424 - 31 (2010)

Grönke, S.; Clarke , D. F.; Broughton, S.; Andrews, T. D.; Partridge, L.: Molecular evolution and functional characterization of Drosophila insulin-like peptides. PLoS Genet 6 (2), p. e1000857 (2010)