Publikationen von N.G. Larsson

Silva, J. P.; Larsson, N.G.: Manipulation of mitochondrial DNA gene expression in the mouse. Biochim Biophys Acta 1555 (1-3), S. 106 - 10 (2002)

Falkenberg, M.; Gaspari, M.; Rantanen, A.; Trifunovic, A.; Larsson, N.G.; Gustafsson, C. M.: Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA. Nat Genet 31 (3), S. 289 - 94 (2002)

Ekstrand, M.; Larsson, N.G.: Breeding and genotyping of Tfam conditional knockout mice. Methods Mol Biol 197, S. 391 - 400 (2002)

Larsson, N.G.; Rustin, P.: Animal models for respiratory chain disease. Trends Mol Med 7 (12), S. 578 - 81 (2001)

Rantanen, A.; Jansson, M.; Oldfors, A.; Larsson, N.G.: Downregulation of Tfam and mtDNA copy number during mammalian spermatogenesis. Mamm Genome 12 (10), S. 787 - 92 (2001)

Sorensen, L.; Ekstrand, M.; Silva, J. P.; Lindqvist, E.; Xu, B.; Rustin, P.; Olson, L.; Larsson, N.G.: Late-onset corticohippocampal neurodepletion attributable to catastrophic failure of oxidative phosphorylation in MILON mice. J Neurosci 21 (20), S. 8082 - 90 (2001)

Wang, J.; Silva, J. P.; Gustafsson, C. M.; Rustin, P.; Larsson, N.G.: Increased in vivo apoptosis in cells lacking mitochondrial DNA gene expression. Proc Natl Acad Sci U S A 98 (7), S. 4038 - 43 (2001)

Silva, J. P.; Kohler, M.; Graff, C.; Oldfors, A.; Magnuson, M. A.; Berggren, P. O.; Larsson, N.G.: Impaired insulin secretion and beta-cell loss in tissue-specific knockout mice with mitochondrial diabetes. Nat Genet 26 (3), S. 336 - 40 (2000)

Rantanen, A.; Larsson, N.G.: Regulation of mitochondrial DNA copy number during spermatogenesis. Hum Reprod 15 Suppl 2, S. 86 - 91 (2000)

Graff, C.; Wredenberg, A.; Silva, J. P.; Bui, T. H.; Borg, K.; Larsson, N.G.: Complex genetic counselling and prenatal analysis in a woman with external ophthalmoplegia and deleted mtDNA. Prenat Diagn 20 (5), S. 426 - 31 (2000)

Li, H.; Wang, J.; Wilhelmsson, H.; Hansson, A.; Thoren, P.; Duffy, J.; Rustin, P.; Larsson, N.G.: Genetic modification of survival in tissue-specific knockout mice with mitochondrial cardiomyopathy. Proc Natl Acad Sci U S A 97 (7), S. 3467 - 72 (2000)

Graff, C.; Clayton, D. A.; Larsson, N.G.: Mitochondrial medicine--recent advances. J Intern Med 246 (1), S. 11 - 23 (1999)

Larsson, N.G.; Luft, R.: Revolution in mitochondrial medicine. FEBS Lett 455 (3), S. 199 - 202 (1999)

Wang, J.; Wilhelmsson, H.; Graff, C.; Li, H.; Oldfors, A.; Rustin, P.; Bruning, J. C.; Kahn, C. R.; Clayton, D. A.; Barsh, G. S. et al.; Thoren, P.; Larsson, N.G.: Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression. Nat Genet 21 (1), S. 133 - 7 (1999)

Larsson, N.G.; Wang, J.; Wilhelmsson, H.; Oldfors, A.; Rustin, P.; Lewandoski, M.; Barsh, G. S.; Clayton, D. A.: Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice. Nat Genet 18 (3), S. 231 - 6 (1998)

Larsson, N.G.; Barsh, G. S.; Clayton, D. A.: Structure and chromosomal localization of the mouse mitochondrial transcription factor A gene (Tfam). Mamm Genome 8 (2), S. 139 - 40 (1997)

Larsson, N.G.; Oldfors, A.; Garman, J. D.; Barsh, G. S.; Clayton, D. A.: Down-regulation of mitochondrial transcription factor A during spermatogenesis in humans. Hum Mol Genet 6 (2), S. 185 - 91 (1997)

Larsson, N.G.; Garman, J. D.; Oldfors, A.; Barsh, G. S.; Clayton, D. A.: A single mouse gene encodes the mitochondrial transcription factor A and a testis-specific nuclear HMG-box protein. Nat Genet 13 (3), S. 296 - 302 (1996)

Houshmand, M.; Larsson, N.G.; Oldfors, A.; Tulinius, M.; Holme, E.: Fatal mitochondrial myopathy, lactic acidosis, and complex I deficiency associated with a heteroplasmic A --> G mutation at position 3251 in the mitochondrial tRNALeu(UUR) gne. Hum Genet 97 (3), S. 269 - 73 (1996)

Oldfors, A.; Moslemi, A. R.; Fyhr, I. M.; Holme, E.; Larsson, N.G.; Lindberg, C.: Mitochondrial DNA deletions in muscle fibers in inclusion body myositis. J Neuropathol Exp Neurol 54 (4), S. 581 - 7 (1995)