Publications of L. S. Tain

Debès, C.; Papadakis, A.; Grönke, S.; Karalay, O.; Tain, L. S.; Mizi, A.; Nakamura, S.; Hahn, O.; Weigelt, C. M.; Josipovic, N. et al.; Zirkel, A.; Brusius, I.; Sofiadis, K.; Lamprousi, M.; Lu, Y.-X.; Huang, W.; Esmaillie, R.; Kubacki, T.; Späth, M. R.; Schermer, B.; Benzing, T.; Müller, R.-U.; Antebi, A.; Partridge, L.; Papantonis, A.; Beyer, A.: Ageing-associated changes in transcriptional elongation influence longevity. Nature (2023)

Tain, L.; Sehlke, R.; Meilenbrock, R. L.; Leech, T.; Paulitz, J.; Chokkalingam, M.; Nagaraj, N.; Grönke, S.; Fröhlich, J.; Atanassov, I. et al.; Mann, M.; Beyer, A.; Partridge, L.: Tissue-specific modulation of gene expression in response to lowered insulin signalling in Drosophila. Elife 10 (2021)

Kapetanou, M.; Nespital, T.; Tain, L.; Pahl, A.; Partridge, L.; Gonos, E. S.: FoxO1 Is a Novel Regulator of 20S Proteasome Subunits Expression and Activity. Front Cell Dev Biol 9, p. 625715 (2021)

Weigelt, C. M.; Sehgal, R.; Tain, L.; Cheng, J.; Esser, J.; Pahl, A.; Dieterich, C.; Grönke, S.; Partridge, L.: An Insulin-Sensitive Circular RNA that Regulates Lifespan in Drosophila. Mol Cell 79 (2), pp. 268 - 279 e5 (2020)

Tain, L.; Jain, C.; Nespital, T.; Fröhlich, J.; Hinze, Y.; Grönke, S.; Partridge, L.: Longevity in response to lowered insulin signaling requires glycine N‐methyltransferase‐dependent spermidine production. Aging Cell 19 (1) (2019)

Castillo-Quan, J. I.; Tain, L.; Kinghorn, K. J.; Li, L.; Grönke, S.; Hinze, Y.; Blackwell , T. K.; Bjedov, I.; Partridge, L.: A triple drug combination targeting components of the nutrient-sensing network maximizes longevity. Proceedings of the National Academy of Sciences of the United States of America 116 (42), pp. 20817 - 20819 (2019)

Brandt, T.; Mourier, A.; Tain, L. S.; Partridge, L.; Larsson, N.G.; Kuhlbrandt, W.: Changes of mitochondrial ultrastructure and function during ageing in mice and Drosophila. Elife 6 (2017)

Tain, L. S.; Sehlke, R.; Jain, C.; Chokkalingam, M.; Nagaraj, N.; Essers, P.; Rassner, M.; Grönke, S.; Froelich, J.; Dieterich, C. et al.; Mann, M.; Alic, N.; Beyer, A.; Partridge, L.: A proteomic atlas of insulin signalling reveals tissue-specific mechanisms of longevity assurance. Mol Syst Biol 13 (9), p. 939 (2017)

Afschar, S.; Toivonen, J. M.; Hoffmann, J. M.; Tain, L. S.; Wieser, D.; Finlayson, A.; Driege, Y.; Alic, N.; Emran, S.; Stinn, J. et al.; Fröhlich, J.; Piper, M. D.; Partridge, L.: Nuclear hormone receptor DHR96 mediates the resistance to xenobiotics but not the increased lifespan of insulin-mutant Drosophila. Proceedings of the National Academy of Sciences 113 (5), pp. 1321 - 1326 (2016)

Castillo-Quan, J. I.; Li, L.; Kinghorn, K. J.; Ivanov, D. K.; Tain, L. S.; Slack, C.; Kerr, F.; Nespital, T.; Thornton, J.; Hardy, J. et al.; Bjedov, I.; Partridge, L.: Lithium Promotes Longevity through GSK3/NRF2-Dependent Hormesis. Cell Rep 15 (3), pp. 638 - 50 (2016)

Essers, P.; Tain, L. S.; Nespital, T.; Goncalves, J.; Fröhlich, J.; Partridge, L.: Reduced insulin/insulin-like growth factor signaling decreases translation in Drosophila and mice. Sci Rep 6, p. 30290 (2016)

Baggio, F.; Bratic, A.; Mourier, A.; Kauppila, T. E. S.; Tain, L. S.; Kukat, C.; Habermann, B.H.; Partridge, L.; Larsson, N.G.: Drosophila melanogaster LRPPRC2 is involved in coordination of mitochondrial translation. Nucleic Acids Res 42 (22), pp. 13920 - 38 (2014)

Metaxakis, A.; Tain, L. S.; Grönke, S.; Hendrich, O.; Hinze, Y.; Birras, U.; Partridge, L.: Lowered insulin signalling ameliorates age-related sleep fragmentation in Drosophila. PLoS Biol 12 (4), p. e1001824 (2014)

Sofola-Adesakin, O.; Castillo-Quan, J. I.; Rallis, C.; Tain, L. S.; Bjedov, I.; Rogers, I.; Li, L.; Martinez, P.; Khericha, M.; Cabecinha, M. et al.; Bahler, J.; Partridge, L.: Lithium suppresses Abeta pathology by inhibiting translation in an adult Drosophila model of Alzheimer's disease. Front Aging Neurosci 6, p. 190 (2014)

Wredenberg, A.; Lagouge, M.; Bratic, A.; Metodiev, M. D.; Spahr, H.; Mourier, A.; Freyer, C.; Ruzzenente, B.; Tain, L. S.; Grönke, S. et al.; Baggio, F.; Kukat, C.; Kremmer, E.; Wibom, R.; Polosa, P. L.; Habermann, B.H.; Partridge, L.; Park, C. B.; Larsson, N.G.: MTERF3 regulates mitochondrial ribosome biogenesis in invertebrates and mammals. PLoS Genet 9 (1), p. e1003178 (2013)