Publications

Journal Article (120)

2021
Journal Article
Bizzarri, D.; Reinders, M. J. T.; Beekman, M.; Slagboom, P. E.; Bbmri, N.; van den Akker, E. B.: 1H-NMR metabolomics-based surrogates to impute common clinical risk factors and endpoints. EBioMedicine 75, p. 103764 (2021)
Journal Article
Zhang, H.; Esposito, M.; Pezet, M. G.; Aryaman, J.; Wei, W.; Klimm, F.; Calabrese, C.; Burr, S. P.; Macabelli, C. H.; Viscomi, C. et al.; Saitou, M.; Chiaratti, M. R.; Stewart, J.; Jones, N.; Chinnery, P. F.: Mitochondrial DNA heteroplasmy is modulated during oocyte development propagating mutation transmission. Sci Adv 7 (50), p. eabi5657 (2021)
Journal Article
Konig, T.; Nolte, H.; Aaltonen, M. J.; Tatsuta, T.; Krols, M.; Stroh, T.; Langer, T.; McBride, H. M.: MIROs and DRP1 drive mitochondrial-derived vesicle biogenesis and promote quality control. Nat Cell Biol 23 (12), pp. 1271 - 1286 (2021)
Journal Article
Demetriadou, C.; Raoukka, A.; Charidemou, E.; Mylonas, C.; Michael, C.; Parekh, S.; Koufaris, C.; Skourides, P.; Papageorgis, P.; Tessarz, P. et al.; Kirmizis, A.: Histone N-terminal acetyltransferase NAA40 links one-carbon metabolism to chemoresistance. Oncogene 41 (4), pp. 571 - 585 (2021)
Journal Article
Albalak, G.; Stijntjes, M.; Wijsman, C. A.; Slagboom, P. E.; van der Ouderaa, F. J.; Mooijaart, S. P.; van Heemst, D.; Noordam, R.: Timing of objectively-collected physical activity in relation to body weight and metabolic health in sedentary older people: a cross-sectional and prospective analysis. Int J Obes (Lond) 46 (3), pp. 515 - 522 (2021)
Journal Article
Lengefeld, J.; Cheng, C. W.; Maretich, P.; Blair, M.; Hagen, H.; McReynolds, M. R.; Sullivan, E.; Majors, K.; Roberts, C.; Kang, J. H. et al.; Steiner, J. D.; Miettinen, T. P.; Manalis, S. R.; Antebi, A.; Morrison, S. J.; Lees, J. A.; Boyer, L. A.; Yilmaz Ö, H.; Amon, A.: Cell size is a determinant of stem cell potential during aging. Sci Adv 7 (46), p. eabk0271 (2021)
Journal Article
Geremia, A.; Sartori, R.; Baraldo, M.; Nogara, L.; Balmaceda, V.; Dumitras, G. A.; Ciciliot, S.; Scalabrin, M.; Nolte, H.; Blaauw, B.: Activation of Akt-mTORC1 signalling reverts cancer-dependent muscle wasting. J Cachexia Sarcopenia Muscle 13 (1), pp. 648 - 661 (2021)
Journal Article
van Vliet, N. A.; Bos, M. M.; Thesing, C. S.; Chaker, L.; Pietzner, M.; Houtman, E.; Neville, M. J.; Li-Gao, R.; Trompet, S.; Mustafa, R. et al.; Ahmadizar, F.; Beekman, M.; Bot, M.; Budde, K.; Christodoulides, C.; Dehghan, A.; Delles, C.; Elliott, P.; Evangelou, M.; Gao, H.; Ghanbari, M.; van Herwaarden, A. E.; Ikram, M. A.; Jaeger, M.; Jukema, J. W.; Karaman, I.; Karpe, F.; Kloppenburg, M.; Meessen, J.; Meulenbelt, I.; Milaneschi, Y.; Mooijaart, S. P.; Mook-Kanamori, D. O.; Netea, M. G.; Netea-Maier, R. T.; Peeters, R. P.; Penninx, B.; Sattar, N.; Slagboom, P. E.; Suchiman, H. E. D.; Völzke, H.; Willems van Dijk, K.; Noordam, R.; van Heemst, D.: Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling. BMC Med 19 (1), p. 266 (2021)
Journal Article
Willenborg, S.; Sanin, D. E.; Jais, A.; Ding, X.; Ulas, T.; Nuechel, J.; Popovic, M.; MacVicar, T.; Langer, T.; Schultze, J. L. et al.; Gerbaulet, A.; Roers, A.; Pearce, E. J.; Bruning, J. C.; Trifunovic, A.; Eming, S. A.: Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing. Cell Metab 33 (12), pp. 2398 - 2414.e9 (2021)
Journal Article
Adams, M.; Sharma, R.; Colby, T.; Weis, F.; Matić, I.; Bhogaraju, S.: Structural basis for protein glutamylation by the Legionella pseudokinase SidJ. Nat Commun 12 (1), p. 6174 (2021)
Journal Article
Li, J.; Wu, X.; Schiffmann, L.; MacVicar, T.; Zhou, C.; Wang, Z.; Li, D.; Camacho, O. V.; Heuchel, R.; Odenthal, M. et al.; Hillmer, A.; Quaas, A.; Zhao, Y.; Bruns, C. J.; Popp, F. C.: IL-17B/RB Activation in Pancreatic Stellate Cells Promotes Pancreatic Cancer Metabolism and Growth. Cancers (Basel) 13 (21) (2021)
Journal Article
Breuer, S.; Kasper, P.; Vohlen, C.; Janoschek, R.; Hoffmann, T.; Appel, S.; Müller-Limberger, E.; Mesaros, A.; Rose-John, S.; Garbers, C. et al.; Müller, S.; Lackmann, J.-W.; Mahabir, E.; Dötsch, J.; Hucklenbruch-Rother, E.; Bae-Gartz, I.: Brain-Restricted Inhibition of IL-6 Trans-Signaling Mildly Affects Metabolic Consequences of Maternal Obesity in Male Offspring. Nutrients 13, p. 3735 (2021)
Journal Article
Demetriades, C.; Nuechel, J.; Plomann, M.: GRASPing the unconventional secretory machinery to bridge cellular stress signaling to the extracellular proteome. Cell Stress 5 (11), pp. 173 - 175 (2021)
Journal Article
Rossetti, G.; Ermer, J. A.; Stentenbach, M.; Siira, S. J.; Richman, T. R.; Milenkovic, D.; Perks, K. L.; Hughes, L. A.; Jamieson, E.; Xiafukaiti, G. et al.; Ward, N. C.; Takahashi, S.; Gray, N.; Viola, H. M.; Hool, L. C.; Rackham, O.; Filipovska, A.: A common genetic variant of a mitochondrial RNA processing enzyme predisposes to insulin resistance. Sci Adv 7 (39), p. eabi7514 (2021)
Journal Article
Pujol, C.; Legrand, A.; Parodi, L.; Thomas, P.; Mochel, F.; Saracino, D.; Coarelli, G.; Croon, M.; Popovic, M.; Valet, M. et al.; Villain, N.; Elshafie, S.; Issa, M.; Zuily, S.; Renaud, M.; Marelli-Tosi, C.; Legendre, M.; Trimouille, A.; Kemlin, I.; Mathieu, S.; Gleeson, J. G.; Lamari, F.; Galatolo, D.; Alkouri, R.; Tse, C.; Rodriguez, D.; Ewenczyk, C.; Fellmann, F.; Kuntzer, T.; Blond, E.; El Hachimi, K. H.; Darios, F.; Seyer, A.; Gazi, A. D.; Giavalisco, P.; Perin, S.; Boucher, J. L.; Le Corre, L.; Santorelli, F. M.; Goizet, C.; Zaki, M. S.; Picaud, S.; Mourier, A.; Steculorum, S. M.; Mignot, C.; Durr, A.; Trifunovic, A.; Stevanin, G.: Implication of folate deficiency in CYP2U1 loss of function. J Exp Med 218 (11) (2021)
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Nespital, T.; Neuhaus, B.; Mesaros, A.; Pahl, A.; Partridge, L.: Lithium can mildly increase health during ageing but not lifespan in mice. Aging Cell 10 (20), p. e13479 (2021)
Journal Article
Hassouneh, F.; Goldeck, D.; Pera, A.; van Heemst, D.; Slagboom, P. E.; Pawelec, G.; Solana, R.: Functional Changes of T-Cell Subsets with Age and CMV Infection. Int J Mol Sci 22 (18) (2021)
Journal Article
Derisbourg, M. J.; Hartman, M. D.; Denzel, M.: Perspective: Modulating the integrated stress response to slow aging and ameliorate age-related pathology. Nat Aging 1 (9), pp. 760 - 768 (2021)
Journal Article
Li, L.; Conradson, D. M.; Bharat, V.; Kim, M. J.; Hsieh, C. H.; Minhas, P. S.; Papakyrikos, A. M.; Durairaj, A. S.; Ludlam, A.; Andreasson, K. I. et al.; Partridge, L.; Cianfrocco, M. A.; Wang, X.: A mitochondrial membrane-bridging machinery mediates signal transduction of intramitochondrial oxidation. Nat Metab 9 (3), pp. 1242 - 1258 (2021)
Journal Article
Škerlová, J.; Berndtsson, J.; Nolte, H.; Ott, M.; Stenmark, P.: Structure of the native pyruvate dehydrogenase complex reveals the mechanism of substrate insertion. Nat Commun 12 (1), p. 5277 (2021)
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