Publications

Remes , C.; Khawaja, A.; Pearce, S. F.; Dinan, A. M.; Gopalakrishna, S.; Cipullo, M.; Kyriakidis, V.; Zhang, J.; Dopico, X. C.; Yukhnovets, O. et al.; Atanassov, I.; Firth, A. E.; Cooperman, B.; Rorbach, J.: Translation initiation of leaderless and polycistronic transcripts in mammalian mitochondria. Nucleic Acids Research (2023)

Krüger, A.; Remes, C.; Shiriaev, D. I.; Liu, Y.; Spåhr, H.; Wibom, R.; Atanassov, I.; Nguyen, M. D.; Cooperman, B. S.; Rorbach, J.: Human mitochondria require mtRF1 for translation termination at non-canonical stop codons. Nature Communications 14, 30 (2023)

Itoh, Y.; Khawaja, A.; Laptev, I.; Cipullo, M.; Atanassov, I.; Sergiev, P.; Rorbach, J.; Amunts, A.: Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature 606 (7914), pp. 603 - 608 (2022)

Erikson, E.; Adori, M.; Khoenkhoen, S.; Zhang, J.; Rorbach, J.; Castro Dopico, X.; Karlsson Hedestam, G.: Impaired plasma cell differentiation associates with increased oxidative metabolism in IkappaBNS-deficient B cells. Cell Immunol 375, p. 104516 (2022)

Cipullo, M.; Gese, G. V.; Khawaja, A.; Hallberg, B. M.; Rorbach, J.: Structural basis for late maturation steps of the human mitoribosomal large subunit. Nat Commun 12 (1), p. 3673 (2021)

Lopez Sanchez, M. I. G.; Kruger, A.; Shiriaev, D. I.; Liu, Y.; Rorbach, J.: Human Mitoribosome Biogenesis and Its Emerging Links to Disease. Int J Mol Sci 22 (8) (2021)

Páleníkova, P.; Harbour, M. E.; Ding, S.; Fearnley, I. M.; Van Haute, L.; Rorbach, J.; Scavetta, R.; Minczuk, M.; Rebelo-Guimar, P.: Quantitative density gradient analysis by mass spectrometry (qDGMS) and complexome profiling analysis (ComPrAn) R package for the study of macromolecular complexes. Methods Mol Biol 2192, pp. 75 - 87 (2021)

Shi, Y.; Yuan, J.; Rraklli, V.; Maxymovitz, E.; Cipullo, M.; Liu, M.; Li, S.; Westerlund, I.; Bedoya-Reina, O. C.; Bullova, P. et al.; Rorbach, J.; Juhlin, C. C.; Stenman, A.; Larsson, C.; Kogner, P.; O'Sullivan, M. J.; Schlisio, S.; Holmberg, J.: Aberrant splicing in neuroblastoma generates RNA-fusion transcripts and provides vulnerability to spliceosome inhibitors. Nucleic Acids Res 49 (5), pp. 2509 - 2521 (2021)

Sighel, D.; Notarangelo, M.; Aibara, S.; Re, A.; Ricci, G.; Guida, M.; Soldano, A.; Adami, V.; Ambrosini, C.; Broso, F. et al.; Rosatti, E. F.; Longhi, S.; Buccarelli, M.; D'Alessandris, Q. G.; Giannetti, S.; Pacioni, S.; Ricci-Vitiani, L.; Rorbach, J.; Pallini, R.; Roulland, S.; Amunts, A.; Mancini, I.; Modelska, A.; Quattrone, A.: Inhibition of mitochondrial translation suppresses glioblastoma stem cell growth. Cell Rep 35 (4), p. 109024 (2021)

Cipullo, M.; Pearce, S. F.; Lopez Sanchez, I. G.; Gopalakrishna, S.; Kruger, A.; Schober, F.; Busch, J. D.; Li, X.; Wredenberg, A.; Atanassov, I. et al.; Rorbach, J.: Human GTPBP5 is involved in the late stage of mitoribosome large subunit assembly. Nucleic Acids Res 49 (1), pp. 354 - 370 (2020)

Pearce, S. F.; Cipullo, M.; Chung, B.; Brierley, I.; Rorbach, J.: Mitoribosome Profiling from Human Cell Culture: A High Resolution View of Mitochondrial Translation. Methods Mol Biol 2192, pp. 183 - 196 (2020)

Lopez Sanchez, M. I. G.; Cipullo, M.; Gopalakrishna, S.; Khawaja, A.; Rorbach, J.: Methylation of Ribosomal RNA: A Mitochondrial Perspective. Front Genet 11, p. 761 (2020)

Khawaja, A.; Itoh, Y.; Remes, C.; Spahr, H.; Yukhnovets, O.; Hofig, H.; Amunts, A.; Rorbach, J.: Distinct pre-initiation steps in human mitochondrial translation. Nat Commun 11 (1), p. 2932 (2020)

Dopico, X. C.; Hanke, L.; Sheward, D. J.; Christian, M.; Muschiol, S.; Grinberg, N. F.; Adori, M.; Vidakovics, L. P.; Kim, C.; Khoenkhoen, S. et al.; Pushparaj, P.; Morro, A. M.; Mandolesi, M.; Forsell, M.; Coquet, J.; Corcoran, M.; Rorbach, J.; Aleman, S.; Bogdanovic, G.; McInerney, G.; Allander, T.; Wallace, C.; Murrell, B.; Albert, J.; Karlsson Hedestam, G. B.: Antibody phenotypes and probabilistic seroprevalence estimates during the emergence of SARS-CoV-2 in Sweden. medRxiv, p. 2020.07.17.20155937 (2020)

Busch, J.; Cipullo, M.; Atanassov, I.; Bratic, A.; Ramos, E.S.; Schöndorf, T.; Li, X.; Pearce, S. F.; Milenkovic, D.; Rorbach, J. et al.; Larsson, N.G.: MitoRibo-Tag Mice Provide a Tool for In Vivo Studies of Mitoribosome Composition. Cell Rep 29 (6), pp. 1728 - 1738 e9 (2019)

Gopalakrishna, S.; Pearce, S. F.; Dinan, A. M.; Schober, F. A.; Cipullo, M.; Spahr, H.; Khawaja, A.; Maffezzini, C.; Freyer, C.; Wredenberg, A. et al.; Atanassov, I.; Firth, A. E.; Rorbach, J.: C6orf203 is an RNA-binding protein involved in mitochondrial protein synthesis. Nucleic Acids Res 47 (17), pp. 9386 - 9399 (2019)

Kruppa, A. J.; Kishi-Itakura, C.; Masters, T. A.; Rorbach, J.; Grice, G. L.; Kendrick-Jones, J.; Nathan, J. A.; Minczuk, M.; Buss, F.: Myosin VI-Dependent Actin Cages Encapsulate Parkin-Positive Damaged Mitochondria. Dev Cell 44 (4), pp. 484 - 499 e6 (2018)

Rorbach, J.; Aibara, S.; Amunts, A.: Ribosome origami. Nat Struct Mol Biol 24 (11), pp. 879 - 881 (2017)

Patel, D.; Rorbach, J.; Downes, K.; Szukszto, M. J.; Pekalski, M. L.; Minczuk, M.: Macropinocytic entry of isolated mitochondria in epidermal growth factor-activated human osteosarcoma cells. Sci Rep 7 (1), p. 12886 (2017)

Garone, C.; D'Souza, A. R.; Dallabona, C.; Lodi, T.; Rebelo-Guiomar, P.; Rorbach, J.; Donati, M. A.; Procopio, E.; Montomoli, M.; Guerrini, R. et al.; Zeviani, M.; Calvo, S. E.; Mootha, V. K.; DiMauro, S.; Ferrero, I.; Minczuk, M.: Defective mitochondrial rRNA methyltransferase MRM2 causes MELAS-like clinical syndrome. Hum Mol Genet 26 (21), pp. 4257 - 4266 (2017)