Max Planck Research Group Pernas

Publications

Mitochondria shed their outer membrane in response to infection-induced stress

  • Li, X.
  • Straub, J.
  • Medeiros, T. C.
  • Mehra, C.
  • den Brave, F.
  • Peker, E.
  • Atanassov, I.
  • Stillger, K.
  • Michaelis, J. B.
  • Burbridge, E.
  • Adrain, C.
  • Munch, C.
  • Riemer, J.
  • Becker, T.
  • Pernas, L. F.
(2022) Science, 375, 6577, eabi4343

A splitCas9 phenotypic screen in Toxoplasma gondii identifies proteins involved in host cell egress and invasion

  • Li, W.
  • Grech, J.
  • Stortz, J. F.
  • Gow, M.
  • Periz, J.
  • Meissner, M.
  • Jimenez-Ruiz, E.
(2022) Nat Microbiol

Cellular metabolism in the defense against microbes

  • Pernas, L.
(2021) J Cell Sci, 134, 5

Move it to lose it: Mitocytosis expels damaged mitochondria

  • Mehra, C.
  • Pernas, L.
(2021) Dev Cell, 56, 14, 2014-2015

Contact and competition between mitochondria and microbes

  • Medeiros, T. C.
  • Mehra, C.
  • Pernas, L.
(2021) Curr Opin Microbiol, 63, 189-194

Mitofusin 1 is required for oocyte growth and communication with follicular somatic cells

  • Carvalho, K. F.
  • Machado, T. S.
  • Garcia, B. M.
  • Zangirolamo, A. F.
  • Macabelli, C. H.
  • Sugiyama, F. H. C.
  • Grejo, M. P.
  • Augusto Neto, J. D.
  • Tostes, K.
  • Ribeiro, F. K. S.
  • Sarapiao, F. D.
  • Pandey, A. K.
  • Nociti, R. P.
  • Tizioto, P.
  • Coutinho, L. L.
  • Meirelles, F. V.
  • Guimaraes, F. E. G.
  • Pernas, L.
  • Seneda, M. M.
  • Chiaratti, M. R.
(2020) FASEB J, 34, 6, 7644-7660

mSphere of Influence: Finding a Direction-How Do Mitochondria Know Where To Go?

  • Pernas, L.
(2019) mSphere, 4(4)

A Toxoplasma gondii locus required for the direct manipulation of host mitochondria has maintained multiple ancestral functions

  • Blank, M. L.
  • Parker, M. L.
  • Ramaswamy, R.
  • Powell, C. J.
  • English, E. D.
  • Adomako-Ankomah, Y.
  • Pernas, L. F.
  • Workman, S. D.
  • Boothroyd, J. C.
  • Boulanger, M. J.
  • Boyle, J. P.
(2018) Mol Microbiol, 108, 5, 519-535

Mitochondria Restrict Growth of the Intracellular Parasite Toxoplasma gondii by Limiting Its Uptake of Fatty Acids

  • Pernas, L.
  • Bean, C.
  • Boothroyd, J. C.
  • Scorrano, L.
(2018) Cell Metab, 27, 4, 886-897 e4

RevAMPing Mitochondrial Shape to Live Longer

  • Pernas, L.
  • Scorrano, L.
(2017) Cell Metab, 26, 6, 805-806

Mito-Morphosis: Mitochondrial Fusion, Fission, and Cristae Remodeling as Key Mediators of Cellular Function

  • Pernas, L.
  • Scorrano, L.
(2016) Annu Rev Physiol, 78, 505-31

Host Mitochondrial Association Evolved in the Human Parasite Toxoplasma gondii via Neofunctionalization of a Gene Duplicate

  • Adomako-Ankomah, Y.
  • English, E. D.
  • Danielson, J. J.
  • Pernas, L. F.
  • Parker, M. L.
  • Boulanger, M. J.
  • Dubey, J. P.
  • Boyle, J. P.
(2016) Genetics, 203, 1, 283-98

Immune profiling of pregnant Toxoplasma-infected US and Colombia patients reveals surprising impacts of infection on peripheral blood cytokines

  • Pernas, L.
  • Ramirez, R.
  • Holmes, T. H.
  • Montoya, J. G.
  • Boothroyd, J. C.
(2014) J Infect Dis, 210, 6, 923-31

Toxoplasma effector MAF1 mediates recruitment of host mitochondria and impacts the host response

  • Pernas, L.
  • Adomako-Ankomah, Y.
  • Shastri, A. J.
  • Ewald, S. E.
  • Treeck, M.
  • Boyle, J. P.
  • Boothroyd, J. C.
(2014) PLoS Biol, 12, 4, e1001845

Association of host mitochondria with the parasitophorous vacuole during Toxoplasma infection is not dependent on rhoptry proteins ROP2/8

  • Pernas, L.
  • Boothroyd, J. C.
(2010) Int J Parasitol, 40, 12, 1367-71