Neurobiology of Ageing

Neurobiology of Ageing


Applied Methods and model organisms

Model Organisms:

Transgenic mouse models, in vitro cell systems

Methods:

  • Cell type-specific ribosome-bound RNA profiling (TRAP) and single cell/nuclei RNA sequencing
  • Chromatin studies, Cut&Run, ATAC-seq, ChIP-sequencing analysis
  • Mouse genetics and behavioral analysis
  • Neuron Glia culture and activity assays (Axiom, Incucyte, Imaris)
  • Immunostaining, brain clearance, in-situ, imaging analysis
  • Molecular systems neuroscience, optogenetics, Ca-imaging in vivo.
  • High resolution microscopy

Neurobiology of Ageing


Applied Methods and model organisms

Model Organisms:

Transgenic mouse models, in vitro cell systems

Methods:

  • Cell type-specific ribosome-bound RNA profiling (TRAP) and single cell/nuclei RNA sequencing
  • Chromatin studies, Cut&Run, ATAC-seq, ChIP-sequencing analysis
  • Mouse genetics and behavioral analysis
  • Neuron Glia culture and activity assays (Axiom, Incucyte, Imaris)
  • Immunostaining, brain clearance, in-situ, imaging analysis
  • Molecular systems neuroscience, optogenetics, Ca-imaging in vivo.
  • High resolution microscopy

Neurobiology of Ageing


Applied Methods and model organisms

Model Organisms:

Transgenic mouse models, in vitro cell systems

Methods:

  • Cell type-specific ribosome-bound RNA profiling (TRAP) and single cell/nuclei RNA sequencing
  • Chromatin studies, Cut&Run, ATAC-seq, ChIP-sequencing analysis
  • Mouse genetics and behavioral analysis
  • Neuron Glia culture and activity assays (Axiom, Incucyte, Imaris)
  • Immunostaining, brain clearance, in-situ, imaging analysis
  • Molecular systems neuroscience, optogenetics, Ca-imaging in vivo.
  • High resolution microscopy

Neurobiology of Ageing


Applied Methods and model organisms

Model Organisms:

Transgenic mouse models, in vitro cell systems

Methods:

  • Cell type-specific ribosome-bound RNA profiling (TRAP) and single cell/nuclei RNA sequencing
  • Chromatin studies, Cut&Run, ATAC-seq, ChIP-sequencing analysis
  • Mouse genetics and behavioral analysis
  • Neuron Glia culture and activity assays (Axiom, Incucyte, Imaris)
  • Immunostaining, brain clearance, in-situ, imaging analysis
  • Molecular systems neuroscience, optogenetics, Ca-imaging in vivo.
  • High resolution microscopy

Applied Methods and model organisms

Model Organisms:

Transgenic mouse models, in vitro cell systems

Methods:

  • Cell type-specific ribosome-bound RNA profiling (TRAP) and single cell/nuclei RNA sequencing
  • Chromatin studies, Cut&Run, ATAC-seq, ChIP-sequencing analysis
  • Mouse genetics and behavioral analysis
  • Neuron Glia culture and activity assays (Axiom, Incucyte, Imaris)
  • Immunostaining, brain clearance, in-situ, imaging analysis
  • Molecular systems neuroscience, optogenetics, Ca-imaging in vivo.
  • High resolution microscopy

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