MAX PLANCK RESEARCH GROUP TESSARZ

Chromatin and Ageing

Chromatin is the complex of DNA and proteins that can be found in the nucleus of a cell. We are very interested in understanding how the architecture of chromatin can regulate gene expression. In particular, we aim to elucidate how age-related changes in the epigenome influence transcriptional outputs and ultimately, cellular fate decisions. Over the recent years, we became fascinated by the connection of other cellular pathways with epigenetic mechanisms and have expanded our research to address the connection between metabolism and inter-organellar communication on chromatin architecture. To this end we combine mechanistic approaches in S. cerevisiae and established cell culture systems with analysis of primary cells and tissues using biochemistry, cell biology and a variety of state-of-the art deep sequencing technologies. [more]

Contact

Max Planck Research Group Leader

Dr. Peter Tessarz

 Email

Third-party funding

  • 2019-2025 Max Planck Society BOOST! program
    (to Chrysa Nikopoulou)

  • 2019-2020 CECAD Seed Funding
    Single-cell epigenomics in the ageing liver

  • 2017-2020 | DFG Research Grant
    H2AQ105 methylation, molecular mechanism of a novel histone modification

  • 2016-2017 | Alexander-von-Humboldt Foundation Postdoctoral Fellowship
    (to Monika Maleszewska)

  • 2013-2016 | BBSRC project grant
    Glutamine methylation and its role in regulating FACT binding to chromatin

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