CV
Scientific Career
2023 - today | Managing Director
Max Planck Institute for Biology of Ageing, Cologne, Germany
2018 - 2023 | Director
Max Planck Institute for Biology of Ageing, Cologne, Germany
2001 - 2017 | Professor (C4/W3)
Institute for Genetics, University of Cologne, Germany
1993 - 2001 | Group leader
Adolf Butenandt Institute for Physiological Chemistry, Ludwig-Maximilians-University of Munich. Chair: Prof. Dr. Dr. Walter Neupert, Germany
1992 - 1993 | Visiting scientist
Memorial Sloan-Kettering Cancer Institute, New York, USA
Education
1999 | Habilitation in Biochemistry
1989 - 1993 | Ph.D.
Ludwig-Maximilians-University of Munich. Mentor: Dr. Franz-Ulrich Hartl. Research topic: Chaperone-mediated protein folding
1984 - 1989 | Study of Biology
University of Regensburg, Germany
Preise/Auszeichnungen
2017 | Max-Delbrück-Preis
- University of Cologne
2017 | EMBO Global Exchange Lecture Series
- China
2016 | Wilhelm Feldberg Prize
- UK
2012 | Elected member
- Leopoldina (German National Akademy of Sciences)
2011 | Elected member
- Nordrhein-Westfälische Akademie der Wissenschaften und Künste
2008 - 2014 | Max Planck Fellow
- Max-Planck-Institut für Biologie des Alterns, Köln
2007 | Elected EMBO member
Drittmittel-Projekte
2021 - 2024 | German Research Council
Collaborative Research Center 1218: Mitochondrial Regulation of Cellular Function
2020 - 2023 | German Research Council
Collaborative Research Center 1403: Cell Death in Immunity, Inflammation and Disease
2020 - 2023 | German-Israel-Project MitoBalance
| Postdoctoral fellowships Humboldt Foundation, EMBO
- Japanese Science Foundation
2015 - 2020 | Reinhart Koselleck-Grant
- German Research Council
2015 - 2020 | Advanced Career Grant
- European Research Council
Scientific Activities / Memberships
Editorial Boards
2002 - 2009 | Biological Chemistry
2010 - today | Journal of Cell Biology, EMBO Reports, Journal of Biochemistry
2012 - 2020 | Board of Reviewing Editors Wissenschaft
Service to Scientific Community
2019 - 2021 | Managing Director
- Max Planck Institute for Biology of Ageing, Cologne
2017 | Pro-Dean for Personnel and Finances
- Faculty of Mathematics and Natures Sciences, University of Cologne
2016 - 2018 | Senator for Cell and Developmental Biology
- German Research Council
2016 - 2018 | Coordinator
- Collaborative Research Center 1218 of
the German Research Council, Mitochondrial regulation of cellular
function, University of Cologne
2013 - 2015 | Vice-President
for Research and Junior Scholars of the University of Cologne
...
Full CV; see https://www.age.mpg.de/langer/biography
Selected publications
Mitochondria regulate intracellular coenzyme Q transport and ferroptotic resistance via STARD7
Deshwal, S., Onishi, M., Tatsuta, T., Bartsch, T., Cors, E., Ried, K., Lemke, K., Nolte, H., Giavalisco, P., Langer, T.
(2023) Nature Cell Biology
OMA1-mediated integrated stress response protects against ferroptosis in mitochondrial cardiomyopathy
Ahola, S., Rivera Mejías, P., Hermans, S., Chandragiri, S., Giavalisco, P., Nolte, H., Langer, T.
(2022) Cell Metabolism, 34, 11, 1875-1891
Regulation of mitochondrial proteostasis by the proton gradient
Patron, M., Tarasenko, D., Nolte. H., Kroczek, L., Ghosh, M.,
Ohba, Y., Lasarzewski, Y., Ahmadi, ZA., Cabrera-Orefice, A., Eyiama, A.,
Kellermann,T., Rugarli, EI., Brandt, U., Meinecke, M., Langer, T.
(2022) EMBO J. 41, 16, e110476
Cellular pyrimidine imbalance triggers mitochondrial DNA–dependent innate immunity
Sprenger, H.-G., MacVicar, T., Bahat, A., Fiedler, K. U.,
Hermans, S., Ehrentraut, D., Ried, K., Milenkovic, D., Bonekamp, N.,
Larsson, N.-G., Nolte, H., Giavalisco, P., Langer, T.
(2021) Nature Metabolism, 3, 5, 636-650
Lipid signalling drives proteolytic rewiring of mitochondria by YME1L
MacVicar, T., Ohba, Y., Nolte, H., Fiona, C. M., Tatsuta, T.,
Sprenger, H. G., Lindner, B., Zhao, Y., Li, J., Bruns, C., Krüger, M.
Habich, M., Riemer, J., Schwarzer, R., Pasparakis, M., Henschke, S.,
Brüning, J. C., Zamboni, N., Langer, T.
(2019) Nature 575, 7782, 361–365
Full publication list; see https://www.age.mpg.de/langer/publications