Publications

Yamada, T.; Ikeda, A.; Murata, D.; Wang, H.; Zhang, C.; Khare, P.; Adachi, Y.; Ito, F.; Quirós, P. M.; Blackshaw, S. et al.; López-Otín, C.; Langer, T.; Chan, D. C.; Le, A.; Dawson, V. L.; Dawson, T. M.; Iijima, M.; Sesaki, H.: Dual regulation of mitochondrial fusion by Parkin–PINK1 and OMA1. Nature (2025)

Pedrera, L.; Prieto Clemente, L.; Dahlhaus, A.; Lotfipour Nasudivar, S.; Tishina, S.; Olmo González, D.; Stroh, J.; Yapici, F. I.; Singh, R. P.; Grotehans, N. et al.; Langer, T.; García-Sáez, A. J.; von Karstedt, S.: Ferroptosis triggers mitochondrial fragmentation via Drp1 activation. Cell Death & Disease 16, 40 (2025)

Tiku, V.; Fakih, Z.; Tatsuta, T.; Jung, M.; Rapaport, D.; Dimmer, K. S.: Characterization of the putative yeast mitochondrial triacylglycerol lipase Tgl2. Journal of Biological Chemistry 301, 108217, p. 108217 (2025)

Martins Garcia, B.; Philipp, M.; Medeiros, T. C.; Hendrix, S.; Prabhu , K.; Corrado, M.; Kingma, J.; Gorbatenko, A.; Deshwal, S.; Veronese, M. et al.; Scorrano, L.; Pearce, E.; Giavalisco, P.; Zelcer, N.; Pernas, L.: Glutamine sensing licenses cholesterol synthesis. The EMBO Journal (2024)

Sawczyc, H.; Tatsuta, T.; Öster, C.; Kosteletos, S.; Lange, S.; Bohg, C.; Langer, T.; Lange, A.: Lipid-polymer nanoparticles to probe the native-like environment of intramembrane rhomboid protease GlpG and its activity. Nature Communications 15, 7533 (2024)

Calabrese, C.; Nolte, H.; Pitman, M. R.; Ganesan, R.; Lampe, P.; Laboy, R.; Ripa, R.; Fischer, J.; Polara, R.; Panda, S. K. et al.; Chipurupalli, S.; Gutierrez, S.; Thomas, D.; Pitson, S. M.; Antebi, A.; Robinson, N.: Mitochondrial translocation of TFEB regulates complex I and inflammation. EMBO Reports (2024)

Ahola, S.; Langer, T.: Ferroptosis in mitochondrial cardiomyopathy. Trends in Cell Biology 34, pp. 150 - 160 (2024)

Ahola, S.; Pazurek, L. A.; Mayer, F. C.; Lampe, P.; Hermans, S.; Becker, L.; Amarie, O. V.; Fuchs, H.; Gailus-Durner, V.; de Angelis, M. H. et al.; Riedel, D.; Nolte, H.; Langer, T.: Opa1 processing is dispensable in mouse development but is protective in mitochondrial cardiomyopathy. Science Advances 10 (2024)

Baker, M. J.; Blau, K. U.; Anderson, A. J.; Palmer, C. S.; Fielden, L. F.; Crameri, J. J.; Milenkovic, D.; Thorburn, D. R.; Frazier, A. E.; Langer, T. et al.; Stojanovski, D.: CLPB disaggregase dysfunction impacts the functional integrity of the proteolytic SPY complex. Journal of Cell Biology 223 (2024)

Henschke, S.; Nolte, H.; Magoley, J.; Kleele, T.; Brandt, C.; Hausen, A. C.; Wunderlich, C. M.; Bauder, C. A.; Aschauer, P.; Manley, S. et al.; Langer, T.; Wunderlich, F. T.; Brüning, J. C.: Food perception promotes phosphorylation of MFFS131 and mitochondrial fragmentation in liver. Science 384, pp. 438 - 446 (2024)

Zaninello, M.; Schlegel, T.; Nolte, H.; Pirzada, M.; Savino, E.; Barth, E.; Klein, I.; Wüstenberg, H.; Uddin, T.; Wolff, L. et al.; Wirth, B.; Lehmann, H. C.; Cioni, J.-M.; Langer, T.; Rugarli, E. I.: CLUH maintains functional mitochondria and translation in motoneuronal axons and prevents peripheral neuropathy. Science Advances 10 (2024)

Grotehans, N.; McGarry, L.; Nolte, H.; Xavier, V.; Kroker, M.; Narbona-Pérez, Á. J.; Deshwal, S.; Giavalisco, P.; Langer, T.; MacVicar, T.: Ribonucleotide synthesis byNME6fuels mitochondrial gene expression. The EMBO Journal (2023)

Kim, J. Y.; Atanassov, I.; Dethloff, F.; Kroczek, L.; Langer, T.: Time-resolved proteomic analyses of senescence highlight metabolic rewiring of mitochondria. Life science alliance 6 (9), e202302127 (2023)

Montoro-Gámez, C.; Nolte, H.; Molinié, T.; Evangelista, G.; Tröder, S.; Barth, E.; Popovic, M.; Trifunovic, A.; Zevnik, B.; Langer, T. et al.; Rugarli, E. I.: SARM1 deletion delays cerebellar but not spinal cord degeneration in an enhanced mouse model ofSPG7deficiency. Brain (2023)

Adriaenssens, E.; Asselbergh, B.; Rivera-Mejías, P.; Bervoets, S.; Vendredy, L.; De Winter, V.; Spaas, K.; de Rycke, R.; van Isterdael, G.; Impens, F. et al.; Langer, T.; Timmerman, V.: Small heat shock proteins operate as molecular chaperones in the mitochondrial intermembrane space. Nature Cell Biology (2023)

Di Sante, M.; Antonucci, S.; Pontarollo, L.; Cappellaro, I.; Segat, F.; Deshwal, S.; Greotti, E.; Grilo, L. F.; Menabò, R.; Di Lisa, F. et al.; Kaludercic, N.: Monoamine oxidase A-dependent ROS formation modulates human cardiomyocyte differentiation through AKT and WNT activation. Basic Research in Cardiology 118, 4 (2023)

Deshwal, S.; Onishi, M.; Tatsuta, T.; Bartsch, T.; Cors, E.; Ried, K.; Lemke, K.; Nolte, H.; Giavalisco, P.; Langer, T.: Mitochondria regulate intracellular coenzyme Q transport and ferroptotic resistance via STARD7. Nature Cell Biology (2023)

Ahola, S.; Langer, T.: Ferroptosis in mitochondrial cardiomyopathy. Trends in Cell Biology (2023)

Chen, W.; Mehlkop, O.; Scharn, A.; Nolte, H.; Klemm, P.; Henschke, S.; Steuernagel, L.; Sotelo-Hitschfeld, T.; Kaya, E.; Wunderlich, C. M. et al.; Langer, T.; Kononenko, N. L.; Giavalisco, P.; Brüning, J. C.: Nutrient-sensing AgRP neurons relay control of liver autophagy during energy deprivation. Cell Metabolism 35, pp. 786 - 806.e13 (2023)

Kohler, A.; Carlström, A.; Nolte, H.; Kohler, V.; Jung, S.-j.; Sridhara, S.; Tatsuta, T.; Berndtsson, J.; Langer, T.; Ott, M.: Early fate decision for mitochondrially encoded proteins by a molecular triage. Molecular Cell (2023)