Publications

Konig, T.; Nolte, H.; Aaltonen, M. J.; Tatsuta, T.; Krols, M.; Stroh, T.; Langer, T.; McBride, H. M.: MIROs and DRP1 drive mitochondrial-derived vesicle biogenesis and promote quality control. Nat Cell Biol 23 (12), pp. 1271 - 1286 (2021)

Geremia, A.; Sartori, R.; Baraldo, M.; Nogara, L.; Balmaceda, V.; Dumitras, G. A.; Ciciliot, S.; Scalabrin, M.; Nolte, H.; Blaauw, B.: Activation of Akt-mTORC1 signalling reverts cancer-dependent muscle wasting. J Cachexia Sarcopenia Muscle 13 (1), pp. 648 - 661 (2021)

Willenborg, S.; Sanin, D. E.; Jais, A.; Ding, X.; Ulas, T.; Nuechel, J.; Popovic, M.; MacVicar, T.; Langer, T.; Schultze, J. L. et al.; Gerbaulet, A.; Roers, A.; Pearce, E. J.; Bruning, J. C.; Trifunovic, A.; Eming, S. A.: Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing. Cell Metab 33 (12), pp. 2398 - 2414.e9 (2021)

Li, J.; Wu, X.; Schiffmann, L.; MacVicar, T.; Zhou, C.; Wang, Z.; Li, D.; Camacho, O. V.; Heuchel, R.; Odenthal, M. et al.; Hillmer, A.; Quaas, A.; Zhao, Y.; Bruns, C. J.; Popp, F. C.: IL-17B/RB Activation in Pancreatic Stellate Cells Promotes Pancreatic Cancer Metabolism and Growth. Cancers (Basel) 13 (21) (2021)

Škerlová, J.; Berndtsson, J.; Nolte, H.; Ott, M.; Stenmark, P.: Structure of the native pyruvate dehydrogenase complex reveals the mechanism of substrate insertion. Nat Commun 12 (1), p. 5277 (2021)

Bahat, A.; MacVicar, T.; Langer, T.: Metabolism and Innate Immunity Meet at the Mitochondria. Front Cell Dev Biol 9, p. 720490 (2021)

Murschall, L. M.; Peker, E.; MacVicar, T.; Langer, T.; Riemer, J.: Protein Import Assay into Mitochondria Isolated from Human Cells. Bio Protoc 11 (12), p. e4057 (2021)

Cretin, E.; Lopes, P.; Vimont, E.; Tatsuta, T.; Langer, T.; Gazi, A.; Sachse, M.; Yu-Wai-Man, P.; Reynier, P.; Wai, T.: High-throughput screening identifies suppressors of mitochondrial fragmentation in OPA1 fibroblasts. EMBO Mol Med 13 (6), p. e13579 (2021)

Nolte, H.; Langer, T.: ComplexFinder: A software package for the analysis of native protein complex fractionation experiments. Biochim Biophys Acta Bioenerg 1862 (8), p. 148444 (2021)

Laborenz, J.; Bykov, Y. S.; Knoringer, K.; Raschle, M.; Filker, S.; Prescianotto-Baschong, C.; Spang, A.; Tatsuta, T.; Langer, T.; Storchova, Z. et al.; Schuldiner, M.; Herrmann, J. M.: The ER protein Ema19 facilitates the degradation of non-imported mitochondrial precursor proteins. Mol Biol Cell 32 (8), pp. 664 - 674 (2021)

Aravamudhan, S.; Turk, C.; Bock, T.; Keufgens, L.; Nolte, H.; Lang, F.; Krishnan, R. K.; Konig, T.; Hammerschmidt, P.; Schindler, N. et al.; Brodesser, S.; Rozsivalova, D. H.; Rugarli, E.; Trifunovic, A.; Bruning, J.; Langer, T.; Braun, T.; Kruger, M.: Phosphoproteomics of the developing heart identifies PERM1 - An outer mitochondrial membrane protein. J Mol Cell Cardiol 154, pp. 41 - 59 (2021)

Eiyama, A.; Aaltonen, M. J.; Nolte, H.; Tatsuta, T.; Langer, T.: Disturbed intramitochondrial phosphatidic acid transport impairs cellular stress signaling. J Biol Chem 296, p. 100335 (2021)

Dennerlein, S.; Poerschke, S.; Oeljeklaus, S.; Wang, C.; Richter-Dennerlein, R.; Sattmann, J.; Bauermeister, D.; Hanitsch, E.; Stoldt, S.; Langer, T. et al.; Jakobs, S.; Warscheid, B.; Rehling, P.: Defining the interactome of the human mitochondrial ribosome identifies SMIM4 and TMEM223 as respiratory chain assembly factors. eLife 10, p. e68213 (2021)

MacVicar, T.; Langer, T.: Mechanometabolism: Mitochondria promote resilience under pressure. Curr Biol 31 (13), pp. R859 - R861 (2021)

Sprenger, H.-G.; MacVicar, T.; Bahat, A.; Fiedler, K. U.; Hermans, S.; Ehrentraut, D.; Ried, K.; Milenkovic, D.; Bonekamp, N.; Larsson, N.G. et al.; Nolte, H.; Giavalisco, P.; Langer, T.: Cellular pyrimidine imbalance triggers mitochondrial DNA–dependent innate immunity. Nature Metabolism 3 (5), pp. 636 - 650 (2021)