Publications

Poláchová, E.; Bach, K.; Heuten, E.; Stanchev, S.; Tichá, A.; Lampe, P.; Majer, P.; Langer, T.; Lemberg, M. K.; Stříšovský, K.: Chemical Blockage of the Mitochondrial Rhomboid Protease PARL by Novel Ketoamide Inhibitors Reveals Its Role in PINK1/Parkin-Dependent Mitophagy. Journal of Medicinal Chemistry (2022)

Jauch, A. S.; Wohlfeil, S. A.; Weller, C.; Dietsch, B.; Häfele, V.; Stojanovic, A.; Kittel, M.; Nolte, H.; Cerwenka, A.; Neumaier, M. et al.; Schledzewski, K.; Sticht, C.; Reiners-Koch, P.-S.; Goerdt, S.; Géraud, C.: Lyve-1 deficiency enhances the hepatic immune microenvironment entailing altered susceptibility to melanoma liver metastasis. Cancer Cell International 22, 398 (2022)

Miliara, X.; Tatsuta, T.; Eiyama, A.; Langer, T.; Rouse, S. L.; Matthews, S.: An intermolecular hydrogen bonded network in the PRELID-TRIAP protein family plays a role in lipid sensing. Biochim Biophys Acta Proteins Proteom 1871 (1), p. 140867 (2022)

Ahola, S.; Rivera Mejias, P.; Hermans, S.; Chandragiri, S.; Giavalisco, P.; Nolte, H.; Langer, T.: OMA1-mediated integrated stress response protects against ferroptosis in mitochondrial cardiomyopathy. Cell Metab 34 (11), pp. 1875 - 1891 e7 (2022)

Mehmedovic, M.; Martucci, M.; Spahr, H.; Ishak, L.; Mishra, A.; Sanchez-Sandoval, M. E.; Pardo-Hernandez, C.; Peter, B.; van den Wildenberg, S. M.; Falkenberg, M. et al.; Farge, G.: Disease causing mutation (P178L) in mitochondrial transcription factor A results in impaired mitochondrial transcription initiation. Biochim Biophys Acta Mol Basis Dis, p. 166467 (2022)

Schatton, D.; Di Pietro, G.; Szczepanowska, K.; Veronese, M.; Marx, M. C.; Braunohler, K.; Barth, E.; Muller, S.; Giavalisco, P.; Langer, T. et al.; Trifunovic, A.; Rugarli, E. I.: CLUH controls astrin-1 expression to couple mitochondrial metabolism to cell cycle progression. Elife 11 (2022)

Croon, M.; Szczepanowska, K.; Popovic, M.; Lienkamp, C.; Senft, K.; Brandscheid, C. P.; Bock, T.; Gnatzy-Feik, L.; Ashurov, A.; Acton, R. J. et al.; Kaul, H.; Pujol, C.; Rosenkranz, S.; Kruger, M.; Trifunovic, A.: FGF21 modulates mitochondrial stress response in cardiomyocytes only under mild mitochondrial dysfunction. Sci Adv 8 (14), p. eabn7105 (2022)

Bette, M.; Cors, E.; Kresse, C.; Schutz, B.: Therapeutic Treatment of Superoxide Dismutase 1 (G93A) Amyotrophic Lateral Sclerosis Model Mice with Medical Ozone Decelerates Trigeminal Motor Neuron Degeneration, …. Int J Mol Sci 23 (6) (2022)

Külshammer, E.; Kilinc, M.; Csordás, G.; Bresser, T.; Nolte, H.; Uhlirova, M.: The mechanosensor Filamin A/Cheerio promotes tumourigenesis via specific interactions with components of the cell cortex. The FEBS Journal 289, pp. 4497 - 4517 (2022)

Manta, C.-P.; Leibing, T.; Friedrich, M.; Nolte, H.; Adrian, M.; Schledzewski, K.; Krzistetzko, J.; Kirkamm, C.; David Schmid, C.; Xi, Y. et al.; Stojanovic, A.; Tonack, S.; de la Torre, C.; Hammad, S.; Offermanns, S.; Krüger, M.; Cerwenka, A.; Platten, M.; Goerdt, S.; Géraud, C.: Targeting of Scavenger Receptors Stabilin-1 and Stabilin-2 Ameliorates Atherosclerosis by a Plasma Proteome Switch Mediating Monocyte/Macrophage Suppression. Circulation 146, pp. 1783 - 1799 (2022)

Vesting, A. J.; Jais, A.; Klemm, P.; Steuernagel, L.; Wienand, P.; Fog-Tonnesen, M.; Hvid, H.; Schumacher, A. L.; Kukat, C.; Nolte, H. et al.; Georgomanolis, T.; Altmüller, J.; Pasparakis, M.; Schmidt, A.; Krüger, M.; Supprian, M. S.; Waisman, A.; Straub, B. K.; Raschzok, N.; Bernier, M.; Birkenfeld, A. L.; Hövelmeyer, N.; Brüning, J. C.; Wunderlich, F. T.: NIK/MAP3K14 in hepatocytes orchestrates NASH to hepatocellular carcinoma progression via JAK2/STAT5 inhibition. Molecular Metabolism 66, 101626, p. 101626 (2022)

Wani, G. A.; Sprenger, H.-G.; Ndoci, K.; Chandragiri, S.; Acton, R. J.; Schatton, D.; Kochan, S. M. V.; Sakthivelu, V.; Jevtic, M.; Seeger, J. M. et al.; Muller, S.; Giavalisco, P.; Rugarli, E. I.; Motori, E.; Langer, T.; Bergami, M.: Metabolic control of adult neural stem cell self-renewal by the mitochondrial protease YME1L. Cell Rep 38 (7), p. 110370 (2022)