Professorin Dr. Anne Schaefer (she/her)

Director

CV

Scientific Career

2021 - today    |    Director
Max Planck Institute for Biology of Ageing, Cologne, Germany
2020 - today    |    Full Professor with Tenure, Vice-Chair of Neuroscience
Co-Director, Center for Glial Biology, Departments of Neuroscience and Psychiatry, Friedman Brain Institute, Mount Sinai School of Medicine, New York, NY
2018 - 2019    |    Associate Professor with Tenure
Co-Director, Center for Glial Biology, Departments of Neuroscience and Psychiatry, Friedman Brain Institute, Mount Sinai School of Medicine, New York, NY
2016 - 2018    |    Associate Professor
Departments of Neuroscience and Psychiatry, Friedman Brain Institute, Mount Sinai School of Medicine, New York, NY
2011 - 2016    |    Assistant Professor
Departments of Neuroscience and Psychiatry, Friedman Brain Institute, Mount Sinai School of Medicine, New York, NY
2009 - 2011    |    Senior Research Associate
Lab. of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY
2007 - 2009    |    Research Associate
Lab. of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY
2004 - 2007    |    Postdoctoral Fellow
Lab. of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY
2001 - 2004    |    Visiting student USA-Scholarship of German National Academic Foundation
Research Advisors: Dr. Michel Nussenzweig (The Rockefeller University, NY), Dr. Ralf Ignatius (Charité, Berlin), The Rockefeller University, New York, NY

Education

1999 - 2004    |    Free University Berlin - Charité, Berlin, Germany
1996 - 1999    |    Johannes Gutenberg University - Mainz, Germany


Awards

2019                |    Max Planck Sabbatical Award      
2019                |    Vice Chair of Neuroscience - Mount Sinai, USA
2018                |    Inventor of the Year 2018 Award - Mount Sinai, USA
2018                |    Inaugural NINDS Landis Award for Outstanding Mentorship - NIH, USA
2017                |    Co-director, Center for Glial Biology - Mount Sinai School of Medicine, USA
2015                |    Harold and Golden Lamport Research Award - Mount Sinai School of Medicine, USA
2014                |    Kavli Frontiers in Science Fellow - The National Academy of Science, USA
2014                |    CURE Challenge Award - USA
2014                |    Technology Development Fund Award - Mount Sinai Innovation, USA
2012                |    NIH Director’s New Innovator Award - USA
2012                |    Seaver Autism Center Research Award - USA
2012                |    named “Chrissy Rossi Investigator”
2011 - 2013    |    NARSAD 2010 Young Investigator Award - USA
2006 - 2008    |    German Research Foundation DFG, Research Fellowship - Germany
2005                |    Hans-Hench Award 2005, German Society for Immunology - Germany
2004                |    Summa cum laude - Charité University Berlin, Germany
2001 - 2003    |    USA-Scholarship of The German National Academic Foundation, (Studienstiftung des deutschen Volkes)
1999 - 2001    |    The German National Academic Foundation (Studienstiftung des deutschen Volkes) Scholarship - Germany


Third-party funding

2021 - 2027    |    European Research Council (Schaefer, Brose, Triller, Oertner MPI) - ERC Synergy Grant,  Micro-'COPS' - Microglia-control of physiological brain states


Selected Publications

Negative feedback control of neuronal activity by microglia
Badimon, A., Strasburger, H. J., Ayata, P., Chen, X., Nair, A., Ikegami, A., Hwang, P., Chan, A. T., Graves, S. M., Uweru, J. O., Ledderose, C., Kutlu, M. G., Wheeler, M. A., Kahan, A., Ishikawa, M., Wang, Y. C., Loh, Y. E., Jiang, J. X., Surmeier, D. J., Robson, S. C., Junger, W. G., Sebra, R., Calipari, E. S., Kenny, P. J., Eyo, U. B., Colonna, M., Quintana, F. J., Wake, H., Gradinaru, V., Schaefer, A.
(2020) Nature, 586, 7829, 417-423

Sensory lesioning induces microglial synapse elimination via ADAM10 and fractalkine signaling
Gunner, G., Cheadle, L., Johnson, K. M., Ayata, P., Badimon, A., Mondo, E., Nagy, M. A., Liu, L., Bemiller, S. M., Kim, K. W., Lira, S. A., Lamb, B. T., Tapper, A. R., Ransohoff, R. M., Greenberg, M. E., Schaefer, A., Schafer, D. P.
(2019) Nat Neurosci, 22, 7, 1075-1088

Epigenetic regulation of brain region-specific microglia clearance activity
Ayata, P., Badimon, A., Strasburger, H. J., Duff, M. K., Montgomery, S. E., Loh, Y. E., Ebert, A., Pimenova, A. A., Ramirez, B. R., Chan, A. T., Sullivan, J. M., Purushothaman, I., Scarpa, J. R., Goate, A. M., Busslinger, M., Shen, L., Losic, B., Schaefer, A.
(2018) Nat Neurosci, 21, 8, 1049-1060

Polycomb repressive complex 2 (PRC2) silences genes responsible for neurodegeneration
von Schimmelmann, M., Feinberg, P. A., Sullivan, J. M., Ku, S. M., Badimon, A., Duff, M. K., Wang, Z., Lachmann, A., Dewell, S., Ma'ayan, A., Han, M. H., Tarakhovsky, A., Schaefer, A.
(2016) Nat Neurosci, 19, 10, 1321-30

MicroRNA-128 governs neuronal excitability and motor behavior in mice
Tan, C. L., Plotkin, J. L., Veno, M. T., von Schimmelmann, M., Feinberg, P., Mann, S., Handler, A., Kjems, J., Surmeier, D. J., O'Carroll, D., Greengard, P., Schaefer, A.
(2013) Science, 342, 6163, 1254-8


Full publication list; see https://www.age.mpg.de/schaefer/publications

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