Publications acknowledging the FACS & Imaging Core Facility

Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitor.
Nicastro R, Brohée L, Alba J, Nüchel J, Figlia G, Kipschull S, Gollwitzer P, Romero-Pozuelo J, Fernandes SA, Lamprakis A, Vanni S, Teleman AA, De Virgilio C, Demetriades C.
(2023) Nat Cell Biol. Aug 10.

Time-resolved proteomic analyses of senescence highlight metabolic rewiring of mitochondria.
Kim JY, Atanassov I, Dethloff F, Kroczek L, Langer T.
(2023) Life Sci Alliance. Jun 15;6(9):e202302127.

Toxicity of C9orf72-associated dipeptide repeat peptides is modified by commonly used protein tags.
Morón-Oset J, Fischer LK, Carcolé M, Giblin A, Zhang P, Isaacs AM, Grönke S, Partridge L.
(2023) Life Sci Alliance. Jun 12;6(9):e202201739.

Hyperspectral Confocal Imaging for High-Throughput Readout and Analysis of Bio-Integrated Laser Particles.
Titze VM, Caixeiro S, Dinh VS, König M, Rübsam M, Pathak N, Niessen CM, Schubert M, Gather MC.
(2023) Protocol Exchange

Functional characterisation of rare variants in genes encoding the MAPK/ERK signalling pathway identified in long-lived Leiden Longevity Study participants.
Hinterding H, Baghdadi M, Gehrmann T, Putter P, Lakenberg N, van den Akker EB, Slagboom PE, Deelen J, Partridge L.
(2023) bioRxiv 2023.06.01.541708

Unbiased evaluation of rapamycin's specificity as an mTOR inhibitor.
Artoni F, Grützmacher N, Demetriades C.
(2023) Aging Cell. Aug;22(8):e13888.

Artificial Hsp104- mediated systems for re-localizing protein aggregates.
Fischbach A, Johns A, Schneider KL, Hao X, Tessarz P, Nyström T.
(2023) Nat Commun. 2023 May 9;14(1):2663.

Parallel phospholipid transfer by Vps13 and Atg2 determines autophagosome biogenesis dynamics.
Dabrowski R, Tulli S, Graef M.
(2023) J Cell Biol. 2023 Jul 3;222(7):e202211039.

Modular antibodies reveal DNA damage- induced mono-ADP-ribosylation as a second wave of PARP1 signaling.
Longarini EJ, Dauben H, Locatelli C, Wondisford AR, Smith R, Muench C, Kolvenbach A, Lynskey ML, Pope A, Bonfiglio JJ, Jurado EP, Fajka-Boja R, Colby T, Schuller M, Ahel I, Timinszky G, O'Sullivan RJ, Huet S, Matic I.
(2023) Mol Cell. 2023 May 18;83(10):1743-1760.e11.

The mitochondrial protease OMA1 acts as a metabolic safeguard upon nuclear DNA damage.
Rivera-Mejías P, Narbona-Pérez ÁJ, Hasberg L, Kroczek L, Bahat A, Lawo S, Folz-Donahue K, Schumacher AL, Ahola S, Mayer FC, Giavalisco P, Nolte H, Lavandero S, Langer T.
(2023) Cell Rep. 2023 Mar 31;42(4):112332.

The dynamic nature of netrin-1 and the structural basis for glycosaminoglycan fragment-induced filament formation.
Meier M, Gupta M, Akgül S, McDougall M, Imhof T, Nikodemus D, Reuten R, Moya-Torres A, To V, Ferens F, Heide F, Padilla-Meier GP, Kukura P, Huang W, Gerisch B, Mörgelin M, Poole K, Antebi A, Koch M, Stetefeld J.
(2023) Nat Commun. 2023 Mar3;14(1):1226.

Cell lineage-specific mitochondrial resilience during mammalian organogenesis
Burr, S.P., Klimm, F., Glynos, A., Prater, M., Sendon, P., Nash, P., Powell, C.A., Simard, M.L., Bonekamp, N.A., Charl, J., Diaz, H., Bozhilova, L.V., Nie, Y., Zhang, H., Frison, M., Falkenberg, M., Jones, N., Minczuk, M., Stewart, J.B., Chinnery, P.F.
(2023) Cell. 2023 Feb 17:S0092-8674(23)00093-4.

Distinct Genetically Determined Origins of Myd88/BCL2-Driven Aggressive Lymphoma Rationalize Targeted Therapeutic Intervention Strategies
Flümann, R., Hansen, J., Pelzer, B.W., Nieper, P., Lohmann, T., Kisis, I., Riet, T., Kohlhas, V., Nguyen, P.H., Peifer, M., Abedpour, N., Bosco, G., Thomas, R.K., Kochanek, M., Knüfer, J., Jonigkeit, L., Beleggia, F., Holzem, A., Büttner, R., Lohneis, P., Meinel, J., Ortmann, M., Persigehl, T., Hallek, M., Calado, D.P., Chmielewski, M., Klein, S., Göthert, J.R., Chapuy, B., Zevnik, B., Wunderlich, F.T., von Tresckow, B., Jachimowicz, R.D., Melnick, A.M., Reinhardt, H.C., Knittel, G.
(2023) Blood Cancer Discov. 2023 Jan 6;4(1):78-97.

Refeeding-associated AMPKy1 complex activity is a hallmark of health and longevity
Ripa, R., Ballhysa, E., Steiner, J.D., Annibal, A., Hochhard, N., Latza, C., Dolfi, L., Calabrese, C., Meyer, A.M., Polidori, M.C., Müller, R.U., Antebi, A.
(2022) bioRxiv 2022.12.05.519139

A metabolite sensor subunit of the Atg1/ULK complex regulates selective autophagy
Gross, A.S., Ghillebert, R., Schuetter, M., Reinartz, E., Rowland, A., Graef, M.
(2022) bioRxiv 2022.12.13.520293

Comprehensive Evaluation of Rapamycin’s Specificity as an mTOR Inhibitor
Artoni, F., Grützmacher. N., Demetriades. C.
(2022) bioRxiv 2022.12.10.519872

Primary cilia suppress Ripk3-mediated necroptosis
Kieckhöfer, E., Slaats, G.G., Ebert, L.K., Albert, M.C., Dafinger, C., Kashkar, H., Benzing, T., Schermer, B.
(2022) Cell Death Discov. 2022 Dec 2;8(1):477.

Sexual identity of enterocytes regulates autophagy to determine intestinal health, lifespan and responses to rapamycin
Regan, J.C., Lu, Y.X., Ureña, E., Meilenbrock, R.L., Catterson, J.H., Kißler, D., Fröhlich, J., Funk, E., Partridge, L.
(2022) Nat Aging 2, 1145–1158

Malonyl-CoA is an ancient physiological ATP-competitive mTORC1 inhibitor
Nicastro, R., Brohée, L., Alba, J,, Nüchel, J,, Figlia, G,, Kipschull, S., Gollwitzer, P., Romero-Pozuelo, J., Fernandes, S.A., Lamprakis, A., Vanni, S., Teleman, A.A., De Virgilio, C., Demetriades, C.
(2022) bioRxiv 2022.11.06.515351

Parallel phospholipid transfer by Vps13 and Atg2 determines autophagosome biogenesis dynamics
Dabrowski, R., Tulli, S., Graef, M.
(2022) bioRxiv 2022.11.10.516013

Hypoxia promotes osteogenesis by facilitating acetyl-CoA-mediated mitochondrial-nuclear communication
Pouikli, A., Maleszewska. M., Parekh. S., Yang, M., Nikopoulou, C., Bonfiglio, J.J., Mylonas, C., Sandoval, T., Schumacher, A.L., Hinze, Y., Matic, I., Frezza, C., Tessarz, P.
(2022) EMBO J. 2022 Dec 1;41(23):e111239.

Go to Editor View