Publications acknowledging the FACS & Imaging Core Facility
Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitor.
Nicastro R, Brohée L, Alba J, Nüchel J, Figlia G, Kipschull S, Gollwitzer P, Romero-Pozuelo J, Fernandes SA, Lamprakis A, Vanni S, Teleman AA, De Virgilio C, Demetriades C.
(2023) Nat Cell Biol. Aug 10.
Time-resolved proteomic analyses of senescence highlight metabolic rewiring of mitochondria.
Kim JY, Atanassov I, Dethloff F, Kroczek L, Langer T.
(2023) Life Sci Alliance. Jun 15;6(9):e202302127.
Toxicity of C9orf72-associated dipeptide repeat peptides is modified by commonly used protein tags.
Morón-Oset J, Fischer LK, Carcolé M, Giblin A, Zhang P, Isaacs AM, Grönke S, Partridge L.
(2023) Life Sci Alliance. Jun 12;6(9):e202201739.
Hyperspectral Confocal Imaging for High-Throughput Readout and Analysis of Bio-Integrated Laser Particles.
Titze VM, Caixeiro S, Dinh VS, König M, Rübsam M, Pathak N, Niessen CM, Schubert M, Gather MC.
(2023) Protocol Exchange
Functional characterisation of rare variants in genes encoding the MAPK/ERK signalling pathway identified in long-lived Leiden Longevity Study participants.
Hinterding H, Baghdadi M, Gehrmann T, Putter P, Lakenberg N, van den Akker EB, Slagboom PE, Deelen J, Partridge L.
(2023) bioRxiv 2023.06.01.541708
Unbiased evaluation of rapamycin's specificity as an mTOR inhibitor.
Artoni F, Grützmacher N, Demetriades C.
(2023) Aging Cell. Aug;22(8):e13888.
Artificial Hsp104- mediated systems for re-localizing protein aggregates.
Fischbach A, Johns A, Schneider KL, Hao X, Tessarz P, Nyström T.
(2023) Nat Commun. 2023 May 9;14(1):2663.
Parallel phospholipid transfer by Vps13 and Atg2 determines autophagosome biogenesis dynamics.
Dabrowski R, Tulli S, Graef M.
(2023) J Cell Biol. 2023 Jul 3;222(7):e202211039.
Modular antibodies reveal DNA damage- induced mono-ADP-ribosylation as a second wave of PARP1 signaling.
Longarini EJ, Dauben H, Locatelli C, Wondisford AR, Smith R, Muench C, Kolvenbach A, Lynskey ML, Pope A, Bonfiglio JJ, Jurado EP, Fajka-Boja R, Colby T, Schuller M, Ahel I, Timinszky G, O'Sullivan RJ, Huet S, Matic I.
(2023) Mol Cell. 2023 May 18;83(10):1743-1760.e11.
The mitochondrial protease OMA1 acts as a metabolic safeguard upon nuclear DNA damage.
Rivera-Mejías P, Narbona-Pérez ÁJ, Hasberg L, Kroczek L, Bahat A, Lawo S, Folz-Donahue K, Schumacher AL, Ahola S, Mayer FC, Giavalisco P, Nolte H, Lavandero S, Langer T.
(2023) Cell Rep. 2023 Mar 31;42(4):112332.
The dynamic nature of netrin-1 and the structural basis for glycosaminoglycan fragment-induced filament formation.
Meier M, Gupta M, Akgül S, McDougall M, Imhof T, Nikodemus D, Reuten R, Moya-Torres A, To V, Ferens F, Heide F, Padilla-Meier GP, Kukura P, Huang W, Gerisch B, Mörgelin M, Poole K, Antebi A, Koch M, Stetefeld J.
(2023) Nat Commun. 2023 Mar3;14(1):1226.
Cell lineage-specific mitochondrial resilience during mammalian organogenesis
Burr, S.P., Klimm, F., Glynos, A., Prater, M., Sendon, P., Nash, P., Powell, C.A., Simard, M.L., Bonekamp, N.A., Charl, J., Diaz, H., Bozhilova, L.V., Nie, Y., Zhang, H., Frison, M., Falkenberg, M., Jones, N., Minczuk, M., Stewart, J.B., Chinnery, P.F.
(2023) Cell. 2023 Feb 17:S0092-8674(23)00093-4.
Distinct Genetically Determined Origins of Myd88/BCL2-Driven Aggressive Lymphoma Rationalize Targeted Therapeutic Intervention Strategies
Flümann, R., Hansen, J., Pelzer, B.W., Nieper, P., Lohmann, T., Kisis, I., Riet, T., Kohlhas, V., Nguyen, P.H., Peifer, M., Abedpour, N., Bosco, G., Thomas, R.K., Kochanek, M., Knüfer, J., Jonigkeit, L., Beleggia, F., Holzem, A., Büttner, R., Lohneis, P., Meinel, J., Ortmann, M., Persigehl, T., Hallek, M., Calado, D.P., Chmielewski, M., Klein, S., Göthert, J.R., Chapuy, B., Zevnik, B., Wunderlich, F.T., von Tresckow, B., Jachimowicz, R.D., Melnick, A.M., Reinhardt, H.C., Knittel, G.
(2023) Blood Cancer Discov. 2023 Jan 6;4(1):78-97.
Refeeding-associated AMPKy1 complex activity is a hallmark of health and longevity
Ripa, R., Ballhysa, E., Steiner, J.D., Annibal, A., Hochhard, N., Latza, C., Dolfi, L., Calabrese, C., Meyer, A.M., Polidori, M.C., Müller, R.U., Antebi, A.
(2022) bioRxiv 2022.12.05.519139
A metabolite sensor subunit of the Atg1/ULK complex regulates selective autophagy
Gross, A.S., Ghillebert, R., Schuetter, M., Reinartz, E., Rowland, A., Graef, M.
(2022) bioRxiv 2022.12.13.520293
Comprehensive Evaluation of Rapamycin’s Specificity as an mTOR Inhibitor
Artoni, F., Grützmacher. N., Demetriades. C.
(2022) bioRxiv 2022.12.10.519872
Primary cilia suppress Ripk3-mediated necroptosis
Kieckhöfer, E., Slaats, G.G., Ebert, L.K., Albert, M.C., Dafinger, C., Kashkar, H., Benzing, T., Schermer, B.
(2022) Cell Death Discov. 2022 Dec 2;8(1):477.
Sexual identity of enterocytes regulates autophagy to determine intestinal health, lifespan and responses to rapamycin
Regan, J.C., Lu, Y.X., Ureña, E., Meilenbrock, R.L., Catterson, J.H., Kißler, D., Fröhlich, J., Funk, E., Partridge, L.
(2022) Nat Aging 2, 1145–1158
Malonyl-CoA is an ancient physiological ATP-competitive mTORC1 inhibitor
Nicastro, R., Brohée, L., Alba, J,, Nüchel, J,, Figlia, G,, Kipschull, S., Gollwitzer, P., Romero-Pozuelo, J., Fernandes, S.A., Lamprakis, A., Vanni, S., Teleman, A.A., De Virgilio, C., Demetriades, C.
(2022) bioRxiv 2022.11.06.515351
Parallel phospholipid transfer by Vps13 and Atg2 determines autophagosome biogenesis dynamics
Dabrowski, R., Tulli, S., Graef, M.
(2022) bioRxiv 2022.11.10.516013
Hypoxia promotes osteogenesis by facilitating acetyl-CoA-mediated mitochondrial-nuclear communication
Pouikli, A., Maleszewska. M., Parekh. S., Yang, M., Nikopoulou, C., Bonfiglio, J.J., Mylonas, C., Sandoval, T., Schumacher, A.L., Hinze, Y., Matic, I., Frezza, C., Tessarz, P.
(2022) EMBO J. 2022 Dec 1;41(23):e111239.
Decreased spliceosome fidelity and egl-8 intron retention inhibit mTORC1 signaling to promote longevity
Huang, W., Kew, C., Fernandes, S.d.A., Löhrke, A., Han, L., Demetriades, C. and Antebi, A.
(2022) Nature Aging 2, 796-808
OMA1-mediated integrated stress response protects against ferroptosis in mitochondrial cardiomyopathy
Ahola, S., Rivera Mejias, P., Hermans, S., Chandragiri, S., Giavalisco, P., Nolte, H. and Langer, T.
(2022) Cell Metab
A Rag GTPase dimer code defines the regulation of mTORC1 by amino acids
Gollwitzer, P., Grutzmacher, N., Wilhelm, S., Kummel, D. and Demetriades, C.
(2022) Nat Cell Biol 24, 1394-1406
Aging is associated with increased chromatin accessibility and reduced polymerase pausing in liver
Bozukova, M., Nikopoulou, C., Kleinenkuhnen, N., Grbavac, D., Goetsch, K. and Tessarz, P.
(2022) Molecular Systems Biology 18, e11002
Long-lasting geroprotection from brief rapamycin treatment in early adulthood by persistently increased intestinal autophagy
Juricic, P., Lu, Y.-X., Leech, T., Drews, L. F., Paulitz, J., Lu, J., Nespital, T., Azami, S., Regan, J.C., Funk, E., Fröhlich, J., Grönke, S. and Partridge, L.
(2022) Nature Aging 2, 824-836
Inhibition of S6K lowers age-related inflammation and immunosenescence and increases lifespan through the endolysosomal system
Zhang, P., Catterson, J.H., Grönke, S. and Partridge, L.
(2022) bioRxiv, 2022.2008.2025.505264
Regulation of mitochondrial proteostasis by the proton gradient
Patron, M., Tarasenko, D., Nolte, H., Kroczek, L., Ghosh, M., Ohba, Y., Lasarzewski, Y., Ahmadi, Z.A., Cabrera-Orefice, A., Eyiama, A., Kellermann, T., Rugarli, E.I., Brandt, U., Meinecke, M. and Langer, T.
(2022) EMBO J 41, e110476
RNA-sequencing of single cholangiocyte-derived organoids reveals high organoid-to organoid variability
Gehling, K., Parekh, S., Schneider, F., Kirchner, M., Kondylis, V., Nikopoulou, C. and Tessarz, P.
(2022) Life Sci Alliance 5
Combined inhibition of EZH2 and ATM is synthetic lethal in BRCA1-deficient breast cancer
Ratz, L., Brambillasca, C., Bartke, L., Huetzen, M.A., Goergens, J., Leidecker, O., Jachimowicz, R.D., van de Ven, M., Proost, N., Siteur, B., de Korte-Grimmerink, R., Bouwman, P., Pulver, E.M., de Bruijn, R., Isensee, J., Hucho, T,. Pandey. G., van Lohuizen, M., Mallmann, P., Reinhardt, H.C., Jonkers, J., Puppe, J.
(2022) Breast Cancer Res. 2022 Jun 17;24(1):41
Mice lacking the mitochondrial exonuclease MGME1 develop inflammatory kidney disease with glomerular dysfunction
Milenkovic, .D, Sanz-Moreno, A., Calzada-Wack, J., Rathkolb, B., Veronica Amarie, O., Gerlini, R., Aguilar-Pimentel, A., Misic, J., Simard, M.L., Wolf, E., Fuchs, H., Gailus-Durner, V., de Angelis, M.H., Larsson, N.G.
(2022) PLoS Genet. 2022 May 9;18(5):e1010190
Full geroprotection from brief rapamycin treatment by persistently increased intestinal autophagy
Juricic, P., Lu, Y.-X., Leech, T., Drews, L.F., Paulitz, J., Lu, J., Nespital, T., Azami, S., Regan, J.C., Funk, E., Fröhlich, J., Grönke, S. and Partridge, L.
(2022) . bioRxiv: 2022.2004.2020.488884
Hypoxia promotes osteogenesis via regulation of the mito-nuclear communication
Pouikli, A., Maleszewska, M., Parekh, S., Nikopoulou, C., Bonfiglio, J.-J., Mylonas, C., Sandoval, T., Schumacher, A.-L., Hinze, Y., Matic, I., Tessarz, P.
(2022) bioRxiv: 2022.2002.2026.482117
GFPT2/GFAT2 and AMDHD2 act in tandem to control the hexosamine pathway
Kroef, V., Ruegenberg, S., Horn, M., Allmeroth, K., Ebert, L., Bozkus, S., Miethe, S., Elling, U., Schermer, B., Baumann, U., Denzel, M.S.
(2022) Elife. 2022 Mar 1;11:e69223
Autophagy regulates neuronal excitability by controlling cAMP/Protein Kinase A signaling
Overhoff, M., Tellkamp, F., Hess, S., Tutas, J., Tolve, M., Faerfers, M., Ickert, L., Mohammadi, M., De Bruyckere, E., Kallergi, E., Dell Vedove, A., Nikoletopoulou, V., Wirth, B., Isensee, J., Hucho, T., Puchkov, D., Isbrandt, D., Krüger, M., Kloppenburg, P., Kononenko, N.L.
(2022) bioRxiv 2022.02.11.480034
Mitochondria shed their outer membrane in response to infection-induced stress
Li, X., Straub, J., Medeiros, T.C., Mehra, C., Brave, F.d., Peker, E., Atanassov, I., Stillger, K., Michaelis, J.B., Burbridge, E., Adrain, C., Münch, C., Riemer, J., Becker, T., Pernas, L.F.
(2022) Science 375(6577):eabi4343
Single-cell resolution unravels spatial alterations in metabolism, transcriptome and epigenome of ageing liver
Nikopoulou, C., Kleinenkuhnen, N., Parekh, S,, Sandoval, T., Schneider, F., Giavalisco, P., Bozukova, M., Vesting, A.J., Altmüller, J., Wunderlich, T., Kondylis, V., Tresch, A., Tessarz, P.
(2021) bioRxiv: 2021.2012.2014.472593
Regulation of mitochondrial proteostasis by the proton gradient
Patron, M., Tarasenko, D., Nolte, H., Ghosh, M., Ohba, Y., Lasarzewski, Y., Ahmadi, Z.A., Cabrera-Orefice, A., Eyiama, A., Kellermann, T., Rugarli, E.I., Brandt, U., Meinecke, M., Langer, T.
(2021) bioRxiv, 2021.2012.2012.470907
Single organoid RNA-sequencing reveals high organoid-to-organoid variability
Gehling, K., Parekh, S., Schneider, S., Kirchner, M., Kondylis, V., Nikopoulou, C., Tessarz, P.
(2021) bioRxiv 2021.11.22.469588
Lengefeld, J., Cheng, C.W., Maretich, P., Blair, M., Hagen, H., McReynolds, M.R., Sullivan, E., Majors, K., Roberts, C., Kang, J.H., Steiner, J.D., Miettinen, T.P., Manalis, S.R., Antebi, A., Morrison, S.J., Lees, J.A., Boyer, L.A., Yilmaz, Ö.H., Amon, A. (2021) Cell size is a determinant of stem cell potential during aging.Sci Adv. 2021 Nov 12;7(46):eabk0271
Gasdermin D mediates host cell death but not interleukin-1β secretion in Mycobacterium tuberculosis-infected macrophages
Theobald, S.J., Gräb, J,, Fritsch, M., Suárez, I., Eisfeld, H.S., Winter, S,, Koch, M., Hölscher, C., Pasparakis, M., Kashkar, H., Rybniker, J.
(2021) Cell Death Discov. 2021 Oct 30;7(1):327
Sexual identity of enterocytes regulates rapamycin-mediated intestinal homeostasis and lifespan extension
Regan, J.C., Lu, Y.X., Ureña, E., Meilenbrock, R., Catterson, J.H., Kißler, D., Partridge, L.
(2021) bioRxiv 2021.10.22.465415
JADE family proteins regulate proteasome abundance and activity
Ebert, L.K., Bargfrede, S., Bohl, K., Müller, R.U., Benzing, T., Schermer, B.
(2021) bioRxiv 2021.10.01.462752
Chromatin remodeling due to degradation of citrate carrier impairs osteogenesis of aged mesenchymal stem cells
Pouikli, A., Parekh, S., Maleszewska, M., Nikopoulou, C., Baghdadi, M., Tripodi, I., Folz-Donahue, K., Hinze, Y., Mesaros, A., Hoey, D., Giavalisco, P., Dowell, R., Partridge, L., Tessarz, P.
(2021) Nat Aging 1, 810–825 (2021)
High levels of TFAM repress mammalian mitochondrial DNA transcription in vivo
Bonekamp, N.A., Jiang, M., Motori, E., Garcia Villegas, R., Koolmeister, C., Atanassov, I., Mesaros, A., Park, C.B., Larsson, N.G.
(2021) Life Sci Alliance. 2021 Aug 30;4(11):e202101034
Sperm cryopreservation and in vitro fertilization techniques for the African turquoise killifish Nothobranchius furzeri
Dolfi, L., Suen, T.K., Ripa, R., Antebi, A.
(2021) Sci Rep. 2021 Aug 25;11(1):17145
NHR-8 and P-glycoproteins uncouple xenobiotic resistance from longevity in chemosensory C. elegans mutants
Guerrero, G.A., Derisbourg, M.J., Mayr, F.A., Wester, L.E., Giorda, M., Dinort, J.E., Hartman, M.D., Schilling, K., Alonso-De Gennaro, M.J., Lu, R.J., Benayoun, B.A., Denzel, M.S.
(2021) Elife. 2021 Aug 27;10:e53174
The anti-apoptotic Bcl-2 protein regulates hair follicle stem cell function
Geueke, A., Mantellato, G., Kuester, F., Schettina, P., Nelles, M., Seeger, J.M., Kashkar, H., Niemann, C.
(2021) EMBO Rep. 2021 Oct 5;22(10):e52301
miR-1 coordinately regulates lysosomal v-ATPase and biogenesis to impact proteotoxicity and muscle function during aging
Schiffer, I., Gerisch, B., Kawamura, K., Laboy, R., Hewitt, J., Denzel, M.S., Mori, M.A., Vanapalli, S., Shen, Y., Symmons, O., Antebi, A.
(2021) Elife. 2021 Jul 27;10:e66768
The RNA-binding protein Puf5 contributes to buffering of mRNA upon chromatin-mediated changes in nascent transcription
Kochan, D.Z., Mawer, J.S.P., Massen, J., Tishinov, K., Parekh, S., Graef, M., Spang, A., Tessarz, P.
(2021) J Cell Sci. 2021 Jul 14:jcs.259051
Niche stiffening compromises hair follicle stem cell potential during ageing by reducing bivalent promoter accessibility
Koester, J., Miroshnikova, Y.A., Ghatak, S., Chacón-Martínez, C.A., Morgner, J., Li, X., Atanassov, I., Altmüller, J., Birk, D.E., Koch, M., Bloch, W., Bartusel, M., Niessen, C.M., Rada-Iglesias, A., Wickström, S.A.
(2021) Nat Cell Biol. 2021 Jul 8
The mitochondrial single-stranded DNA binding protein is essential for initiation of mtDNA replication
Jiang, M., Xie, X., Zhu, X., Jiang, S., Milenkovic, D., Misic, J., Shi, Y., Tandukar, N., Li, X., Atanassov, I., Jenninger, L., Hoberg, E,. Albarran-Gutierrez, S., Szilagyi, Z., Macao, B., Siira, S.J., Carelli, V., Griffith, J.D., Gustafsson, C.M., Nicholls, T.J., Filipovska, A., Larsson, N.G., Falkenberg, M.
(2021) Sci Adv. 2021 Jul 2;7(27):eabf8631
Calcium signaling mediates a biphasic mechanoadaptive response of endothelial cells to cyclic mechanical stretch
Miroshnikova, Y.A., Manet, S., Li, X., Wickström, S.A., Faurobert, E., Albiges-Rizo, C.
(2021) Mol Biol Cell. 2021 Jun 3
A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageing
Lu, Y.X., Regan, J.C., Eßer, J., Drews, L.F., Weinseis, T., Stinn, J., Hahn, O., Miller, R.A., Grönke, S., Partridge, L.
(2021) Elife. 2021 May 14
Innovative robust basophil activation test using a novel gating strategy reliably diagnosing allergy with full automation
Behrends, J., Schwager, C., Hein, M., Scholzen, T., Kull, S., Jappe, U.
(2021) Allergy. 2021 May 11
N1-acetylspermidine is a determinant of hair follicle stem cell fate
Allmeroth, K., Kim, C.S., Annibal, A., Pouikli, A., Koester, J., Derisbourg, M.J., Andrés Chacón-Martínez, C., Latza, C., Antebi, A., Tessarz. P., Wickström, S.A., Denzel, M.S.
(2021) J Cell Sci. 2021 May 1;134(9)
Cellular pyrimidine imbalance triggers mitochondrial DNA-dependent innate immunity
Sprenger, H.G., MacVicar, T., Bahat. A., Fiedler, F.U,, Hermans, S,, Ehrentraut, D., Ried, K., Milenkovic, D., Bonekamp, N., Larsson, N.G., Nolte, H., Giavalisco, P., Langer, T.
(2021) Nat Metab. 2021 Apr 26
GFAT2 and AMDHD2 act in tandem to control the hexosamine biosynthetic pathway
Kroef, V., Ruegenberg, S., Horn, M., Allmeroth, K., Ebert, L., Bozkus, S., Miethe, S., Schermer, B., Baumann, U., Denzel, M.S.
(2021) bioRxiv 2021.04.23.441115
Tissue-specific modulation of gene expression in response to lowered insulin signalling in Drosophila
Tain, L.S., Sehlke, R., Meilenbrock, R.L., Leech, T., Paulitz, J., Chokkalingam, M., Nagaraj, N., Grönke, S., Fröhlich, J., Atanassov, I., Mann, M., Beyer, A., Partridge, L.
(2021) Elife. 2021 Apr 21;10:e67275
Sperm cryopreservation and in vitro fertilization techniques for the African turquoise killifish Nothobranchius furzeri
Dolfi, L., Suen, T.K.,Ripa, R-, Antebi, S.
(2021) Research Square
miR-1 coordinately regulates lysosomal v-ATPase and biogenesis to affect muscle contractility upon proteotoxic challenge during ageing
Schiffer, I., Gerisch, B., Kawamura, K., Laboy, R., Hewitt, J., Denzel, M.S., Mori, M.A., Vanapalli, S., Shen, Y., Symmons, O., Antebi, A.
(2021) bioRxiv 2021.01.21.427623
Sestrin is a key regulator of stem cell function and lifespan in response to dietary amino acids
Lu, J., Temp, U., Müller-Hartmann, A., Esser, J., Grönke, S., Partridge, L.
(2021) Nature Aging 1, 60–72 (2021)
An HPF1/PARP1-Based Chemical Biology Strategy for Exploring ADP-Ribosylation
Bonfiglio, J.J., Leidecker, O., Dauben, H., Longarini, E.J., Colby, T., San Segundo-Acosta, P., Perez, K.A., Matic, I.
(2020) Cell. 2020 Nov 12;183(4):1086-1102.e23
Neuronal metabolic rewiring promotes resilience to neurodegeneration caused by mitochondrial dysfunction
Motori, E., Atanassov, I., Kochan, S.M.V., Folz-Donahue, K., Sakthivelu, V., Giavalisco, P., Toni, N., Puyal, J., Larsson, N.G.
(2020) .Sci Adv. 2020 Aug 28;6(35):eaba8271
Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle
Kim, C.S., Ding, X., Allmeroth, K., Biggs, L.C., Kolenc, O.I., L'Hoest, N., Chacón-Martínez, C.A., Edlich-Muth, C., Giavalisco, P., Quinn, K.P., Denzel, M.S., Eming, S.A., Wickström, S.A.
(2020) Cell Metab. 2020 Oct 6;32(4):629-642.e8
Dnmt3a2/Dnmt3L Overexpression in the Dopaminergic System of Mice Increases Exercise Behavior through Signaling Changes in the Hypothalamus
Cui, D., Mesaros, A., Burdeos, G., Voigt, I., Giavalisco, P., Hinze, Y., Purrio, M., Neumaier, B., Drzezga, A., Obata, Y., Endepols, H., Xu, X.
(2020) .Int J Mol Sci. 2020 Aug 31;21(17):6297
Disease-Specific Expression of Conjunctiva Associated Lymphoid Tissue (CALT) in Mouse Models of Dry Eye Disease and Ocular Allergy
Steven, P., Schwab, S., Kiesewetter, A., Saban, D.R., Stern, M.E., Gehlsen, U.
(2020) Int J Mol Sci. 2020 Oct 12;21(20):E7514
The RNA-binding protein Puf5 buffers mRNA levels against chromatin-mediated changes in nascent transcription
Kochan, D.Z., Mawer, J.S.P., Tishinov, K., Parekh, S., Massen, J., Graef, M., Spang, A., Tessarz, P.
(2020) bioRxiv 10.1101/2020.08.13.249912
Optimization of cryopreservation and in vitro fertilization techniques for the African turquoise killifish Nothobranchius furzeri
Dolfi, L., Suen, T.K., Ripa, R., Antebi, A.
(2020) bioRxiv 10.1101/2020.04.14.040824
Bortezomib resistance mutations in PSMB5 determine response to second-generation proteasome inhibitors in multiple myeloma
Allmeroth, K., Horn, M., Kroef, V., Miethe, S., Müller, R.U., Denzel, M.S.
(2020) Leukemia. 2020 Jul 20
Epidermal stratification is uncoupled from centrosome-dependent cell division orientation of the basal progenitors
Damen, M., Soroka, E., Khatif, H., Kukat, C., Simons, B.D., Bazzi, H.
(2020) bioRxiv 10.1101/2020.07.24.219493
FBXL4 deficiency increases mitochondrial removal by autophagy
Alsina, D., Lytovchenko, O., Schab, A., Atanassov, I., Schober, F.A., Jiang, M., Koolmeister, C., Wedell, A., Taylor, R.W., Wredenberg, A., Larsson, N.G.
(2020) EMBO Mol Med. 2020 Jul 7;12(7):e11659
NFYB-1 regulates mitochondrial function and longevity via lysosomal prosaposin
Tharyan, R.G., Annibal, A., Schiffer, I., Laboy, R., Atanassov, I., Weber, A.L., Gerisch, B., Antebi, A.
(2020) Nat Metab. 2020 May;2(5):387-396
HLH-30/TFEB Is a Master Regulator of Reproductive Quiescence
Gerisch, B., Tharyan, R. G., Mak, J., Denzel, S. I., Popkes-van Oepen, T., Henn, N. and Antebi, A.
(2020) Developmental cell, 53(3), 316–329.e5
Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage
Nava, M.M., Miroshnikova, Y.A., Biggs, L.C., Whitefield, D.B., Metge, F., Boucas, J., Vihinen, H., Jokitalo, E., Li, X., García Arcos, J.M., Hoffmann, B., Merkel, R., Niessen, C.M., Dahl, K.N. and Wickström, S.A. (2020) Cell, 181(4), 800–817.e22
Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis
Ruegenberg, S., Horn, M., Pichlo, C., Allmeroth, K., Baumann, U. and Denzel, M. S.
(2020) Nature communications, 11(1), 687
Local Fatty Acid Channeling into Phospholipid Synthesis Drives Phagophore Expansion during Autophagy
Schütter, M., Giavalisco, P., Brodesser, S. and Graef, M.
(2020) Cell, 180(1), 135–149.e14
Glycine-alanine dipeptide repeats spread rapidly in a repeat length- and age-dependent manner in the fly brain
Morón-Oset, J., Supèr, T., Esser, J., Isaacs, A. M., Grönke, S. and Partridge, L.
(2019) Acta neuropathologica communications, 7(1), 209
Cell cycle dynamics during diapause entry and exit in an annual killifish revealed by FUCCI technology
Dolfi, L., Ripa, R., Antebi, A., Valenzano, D. R. and Cellerino, A.
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