Publications

Deshwal, S.; Onishi, M.; Tatsuta, T.; Bartsch, T.; Cors, E.; Ried, K.; Lemke, K.; Nolte, H.; Giavalisco, P.; Langer, T.: Mitochondria regulate intracellular coenzyme Q transport and ferroptotic resistance via STARD7. Nature Cell Biology (2023)

Dalmasso, M. C.; Arán, M.; Galeano, P.; Perin, S.; Giavalisco, P.; Martino Adami, P. V.; Novack, G. V.; Castaño, E. M.; Cuello, A. C.; Scherer, M. et al.; Maier, W.; Wagner, M.; Riedel-Heller, S.; Ramirez, A.; Morelli, L.: Nicotinamide as potential biomarker for Alzheimer’s disease: A translational study based on metabolomics. Frontiers in Molecular Biosciences 9 (2023)

Chen, W.; Mehlkop, O.; Scharn, A.; Nolte, H.; Klemm, P.; Henschke, S.; Steuernagel, L.; Sotelo-Hitschfeld, T.; Kaya, E.; Wunderlich, C. M. et al.; Langer, T.; Kononenko, N. L.; Giavalisco, P.; Brüning, J. C.: Nutrient-sensing AgRP neurons relay control of liver autophagy during energy deprivation. Cell Metabolism 35, pp. 786 - 806.e13 (2023)

Hanssen, R.; Rigoux, L.; Albus, K.; Kretschmer, A. C.; Edwin Thanarajah, S.; Chen, W.; Hinze, Y.; Giavalisco, P.; Steculorum, S. M.; Cornely, O. A. et al.; Brüning, J. C.; Tittgemeyer, M.: Circulating uridine dynamically and adaptively regulates food intake in humans. Cell Reports Medicine 4, 100897, p. 100897 (2023)

Park, S.; Belfoul, A. M.; Rastelli, M.; Jang, A.; Monnoye, M.; Bae, H.; Kamitakahara, A.; Giavalisco, P.; Sun, S.; Barelle, P.-Y. et al.; Plows, J.; Jang, C.; Fodor, A.; Goran, M. I.; Bouret, S. G.: Maternal low-calorie sweetener consumption rewires hypothalamic melanocortin circuits via a gut microbial co-metabolite pathway. JCI Insight 8 (2023)

Rivera Mejias, P.; Narbona-Pérez, Á. J.; Hasberg, L.; Kroczek, L.; Bahat, A.; Lawo, S.; Folz-Donahue, K.; Schumacher, A. L.; Ahola, S.; Mayer, F. C. et al.; Giavalisco, P.; Nolte, H.; Lavandero, S.; Langer, T.: The mitochondrial protease OMA1 acts as a metabolic safeguard upon nuclear DNA damage. Cell Reports 42, 112332, p. 112332 (2023)

Pouikli, A.; Maleszewska, M.; Parekh, S.; Yang, M.; Nikopoulou, C.; Bonfiglio, J. J.; Mylonas, C.; Sandoval, T.; Schumacher, A. L.; Hinze, Y. et al.; Matić, I.; Frezza, C.; Tessarz, P.: Hypoxia promotes osteogenesis by facilitating acetyl-CoA-mediated mitochondrial-nuclear communication. EMBO J, p. e111239 (2022)

Dai, L.; Wang, B.; Wang, T.; Meyer, E. H.; Kettel, V.; Hoffmann, N.; McFarlane, H. E.; Li, S.; Wu, X.; Picard, K. L. et al.; Giavalisco, P.; Persson, S.; Zhang, Y.: The TOR complex controls ATP levels to regulate actin cytoskeleton dynamics in Arabidopsis. Proc Natl Acad Sci U S A 119 (38), p. e2122969119 (2022)

Ahola, S.; Rivera Mejias, P.; Hermans, S.; Chandragiri, S.; Giavalisco, P.; Nolte, H.; Langer, T.: OMA1-mediated integrated stress response protects against ferroptosis in mitochondrial cardiomyopathy. Cell Metab 34 (11), pp. 1875 - 1891 e7 (2022)

Schatton, D.; Di Pietro, G.; Szczepanowska, K.; Veronese, M.; Marx, M. C.; Braunohler, K.; Barth, E.; Muller, S.; Giavalisco, P.; Langer, T. et al.; Trifunovic, A.; Rugarli, E. I.: CLUH controls astrin-1 expression to couple mitochondrial metabolism to cell cycle progression. Elife 11 (2022)

Hausl, A. S.; Bajaj, T.; Brix, L. M.; Pohlmann, M. L.; Hafner, K.; De Angelis, M.; Nagler, J.; Dethloff, F.; Balsevich, G.; Schramm, K. W. et al.; Giavalisco, P.; Chen, A.; Schmidt, M. V.; Gassen, N. C.: Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabolism. Sci Adv 8 (10), p. eabi4797 (2022)

Pouikli, A.; Maleszewska, M.; Parekh, S.; Nikopoulou, C.; Bonfiglio, J. J.; Mylonas, C.; Sandoval, T.; Hinze, Y.; Matić, I.; Tessarz, P.: Hypoxia promotes osteogenesis via regulation of the mito-nuclear communication. bioRxiv 2022.2002.2026.482117 (2022)

Mennuni, M.; Filograna, R.; Felser, A.; Bonekamp, N. A.; Giavalisco, P.; Lytovchenko, O.; Larsson, N.G.: Metabolic resistance to the inhibition of mitochondrial transcription revealed by CRISPR-Cas9 screen. EMBO Rep 23 (1), p. e53054 (2022)

Siemiatkowska, B.; Chiara, M.; Badiger, B. G.; Riboni, M.; D'Avila, F.; Braga, D.; Salem, M. A. A.; Martignago, D.; Colanero, S.; Galbiati, M. et al.; Giavalisco, P.; Tonelli, C.; Juenger, T. E.; Conti, L.: GIGANTEA Is a Negative Regulator of Abscisic Acid Transcriptional Responses and Sensitivity in Arabidopsis. Plant Cell Physiol 63 (9), pp. 1285 - 1297 (2022)

Stepan, J.; Heinz, D. E.; Dethloff, F.; Bajaj, T.; Zellner, A.; Hafner, K.; Wiechmann, S.; Mackert, S.; Mecdad, Y.; Rabenstein, M. et al.; Ebert, T.; Martinelli, S.; Häusl, A. S.; Pöhlmann, M. L.; Hermann, A.; Ma, X.; Pavenstädt, H.; Schmidt, M. V.; Philipsen, A.; Turck, C. W.; Deussing, J. M.; Kuster, B.; Wehr, M. C.; Stein, V.; Kremerskothen, J.; Wotjak, C. T.; Gassen, N. C.: Hippo-released WWC1 facilitates AMPA receptor regulatory complexes for hippocampal learning. Cell Reports 41, 111766, p. 111766 (2022)

Wani, G. A.; Sprenger, H.-G.; Ndoci, K.; Chandragiri, S.; Acton, R. J.; Schatton, D.; Kochan, S. M. V.; Sakthivelu, V.; Jevtic, M.; Seeger, J. M. et al.; Muller, S.; Giavalisco, P.; Rugarli, E. I.; Motori, E.; Langer, T.; Bergami, M.: Metabolic control of adult neural stem cell self-renewal by the mitochondrial protease YME1L. Cell Rep 38 (7), p. 110370 (2022)

Pujol, C.; Legrand, A.; Parodi, L.; Thomas, P.; Mochel, F.; Saracino, D.; Coarelli, G.; Croon, M.; Popovic, M.; Valet, M. et al.; Villain, N.; Elshafie, S.; Issa, M.; Zuily, S.; Renaud, M.; Marelli-Tosi, C.; Legendre, M.; Trimouille, A.; Kemlin, I.; Mathieu, S.; Gleeson, J. G.; Lamari, F.; Galatolo, D.; Alkouri, R.; Tse, C.; Rodriguez, D.; Ewenczyk, C.; Fellmann, F.; Kuntzer, T.; Blond, E.; El Hachimi, K. H.; Darios, F.; Seyer, A.; Gazi, A. D.; Giavalisco, P.; Perin, S.; Boucher, J. L.; Le Corre, L.; Santorelli, F. M.; Goizet, C.; Zaki, M. S.; Picaud, S.; Mourier, A.; Steculorum, S. M.; Mignot, C.; Durr, A.; Trifunovic, A.; Stevanin, G.: Implication of folate deficiency in CYP2U1 loss of function. J Exp Med 218 (11) (2021)

Alseekh, S.; Aharoni, A.; Brotman, Y.; Contrepois, K.; D'Auria, J.; Ewald, J.; J, C. E.; Fraser, P. D.; Giavalisco, P.; Hall, R. D. et al.; Heinemann, M.; Link, H.; Luo, J.; Neumann, S.; Nielsen, J.; Perez de Souza, L.; Saito, K.; Sauer, U.; Schroeder, F. C.; Schuster, S.; Siuzdak, G.; Skirycz, A.; Sumner, L. W.; Snyder, M. P.; Tang, H.; Tohge, T.; Wang, Y.; Wen, W.; Wu, S.; Xu, G.; Zamboni, N.; Fernie, A. R.: Mass spectrometry-based metabolomics: a guide for annotation, quantification and best reporting practices. Nat Methods 18 (7), pp. 747 - 756 (2021)

Sieben, A.; Hausen, A. C.; Klemm, P.; Jais, A.; Heilinger, C.; Alber, J.; Folz-Donahue, K.; Schumacher, L.; Altmüller, J.; Franitza, M. et al.; Giavalisco, P.; Hinze, Y.; Brodesser, S.; Kukat, C.; Theurich, S.; Brüning, J. C.: P2Y6 receptor signaling in natural killer cells impairs insulin sensitivity in obesity. bioRxiv, p. 2021.06.23.449596 (2021)

Gassen, N. C.; Papies, J.; Bajaj, T.; Emanuel, J.; Dethloff, F.; Chua, R. L.; Trimpert, J.; Heinemann, N.; Niemeyer, C.; Weege, F. et al.; Honzke, K.; Aschman, T.; Heinz, D. E.; Weckmann, K.; Ebert, T.; Zellner, A.; Lennarz, M.; Wyler, E.; Schroeder, S.; Richter, A.; Niemeyer, D.; Hoffmann, K.; Meyer, T. F.; Heppner, F. L.; Corman, V. M.; Landthaler, M.; Hocke, A. C.; Morkel, M.; Osterrieder, N.; Conrad, C.; Eils, R.; Radbruch, H.; Giavalisco, P.; Drosten, C.; Muller, M. A.: SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals. Nat Commun 12 (1), p. 3818 (2021)