Research Group Deelen
Journal Article (98)
2014
Journal Article
23 (16), pp. 4420 - 32 (2014)
Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age. Hum Mol Genet
Journal Article
43 (3), pp. 878 - 86 (2014)
Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers. Int J Epidemiol 2013
Journal Article
16 (6), pp. 1026 - 32 (2013)
Aging as accelerated accumulation of somatic variants: whole-genome sequencing of centenarian and middle-aged monozygotic twin pairs. Twin Res Hum Genet
Journal Article
62 (9), pp. 3275 - 81 (2013)
The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway. Diabetes
Journal Article
45 (4), pp. 422/7, 427e1 - 2 (2013)
Identification of seven loci affecting mean telomere length and their association with disease. Nat Genet
Journal Article
8 (2), p. e56262 (2013)
Non-homologous end-joining pathway associated with occurrence of myocardial infarction: gene set analysis of genome-wide association study data. PLoS One
Journal Article
35 (4), pp. 386 - 96 (2013)
Identifying the genomic determinants of aging and longevity in human population studies: progress and challenges. Bioessays
Journal Article
9 (2), p. e1003266 (2013)
A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function. PLoS Genet
Journal Article
21 (10), pp. 1163 - 8 (2013)
Meta-analysis of telomere length in 19,713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect. Eur J Hum Genet
Journal Article
12 (2), pp. 184 - 93 (2013)
Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study. Aging Cell 2012
Journal Article
12 (1), pp. 24 - 31 (2012)
Gene expression analysis of mTOR pathway: association with human longevity. Aging Cell
Journal Article
67 (11), pp. 1153 - 60 (2012)
Distinguishing between longevity and buffered-deleterious genotypes for exceptional human longevity: the case of the MTP gene. J Gerontol A Biol Sci Med Sci
Journal Article
7 (1), p. e27759 (2012)
Transcriptional profiling of human familial longevity indicates a role for ASF1A and IL7R. PLoS One 2011
Journal Article
20 (5), pp. 572 - 6 (2011)
How to deal with the early GWAS data when imputing and combining different arrays is necessary. Eur J Hum Genet
Journal Article
35 (1), pp. 235 - 49 (2011)
Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways. Age (Dordr)
Journal Article
20 (23), pp. 4748 - 57 (2011)
A genome-wide association study identifies a region at chromosome 12 as a potential susceptibility locus for restenosis after percutaneous coronary intervention. Hum Mol Genet
Journal Article
10 (4), pp. 686 - 98 (2011)
Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited. Aging Cell 2010
Journal Article
366 (1561), pp. 35 - 42 (2010)
Genomics of human longevity. Philos Trans R Soc Lond B Biol Sci