Publications

Klaric, J. A.; Wüst, S.; Panier, S.: New Faces of old Friends: Emerging new Roles of RNA-Binding Proteins in the DNA Double-Strand Break Response. Front Mol Biosci 8, p. 668821 (2021)

Panier, S.; Maric, M.; Hewitt, G.; Mason-Osann, E.; Gali, H.; Dai, A.; Labadorf, A.; Guervilly, J. H.; Ruis, P.; Segura-Bayona, S. et al.; Belan, O.; Marzec, P.; Gaillard, P. H. L.; Flynn, R. L.; Boulton, S. J.: SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance. Mol Cell 76 (1), pp. 27 - 43 e11 (2019)

Leon-Ortiz, A. M.; Panier, S.; Sarek, G.; Vannier, J. B.; Patel, H.; Campbell, P. J.; Boulton, S. J.: A Distinct Class of Genome Rearrangements Driven by Heterologous Recombination. Mol Cell 69 (2), pp. 292 - 305 e6 (2018)

Margalef, P.; Kotsantis, P.; Borel, V.; Bellelli, R.; Panier, S.; Boulton, S. J.: Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe. Cell 172 (3), pp. 439 - 453 e14 (2018)

Kitevski-LeBlanc, J.; Fradet-Turcotte, A.; Kukic, P.; Wilson, M. D.; Portella, G.; Yuwen, T.; Panier, S.; Duan, S.; Canny, M. D.; van Ingen, H. et al.; Arrowsmith, C. H.; Rubinstein, J. L.; Vendruscolo, M.; Durocher, D.; Kay, L. E.: The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage. Elife 6 (2017)

Sarek, G.; Vannier, J. B.; Panier, S.; Petrini, J. H. J.; Boulton, S. J.: TRF2 Recruits RTEL1 to Telomeres in S Phase to Promote T-Loop Unwinding. Mol Cell 61 (5), pp. 788 - 789 (2016)

Sarek, G.; Vannier, J. B.; Panier, S.; Petrini, J. H. J.; Boulton, S. J.: TRF2 recruits RTEL1 to telomeres in S phase to promote t-loop unwinding. Mol Cell 57 (4), pp. 622 - 635 (2015)

Panier, S.; Boulton, S. J.: Double-strand break repair: 53BP1 comes into focus. Nat Rev Mol Cell Biol 15 (1), pp. 7 - 18 (2013)

Bohgaki, M.; Bohgaki, T.; El Ghamrasni, S.; Srikumar, T.; Maire, G.; Panier, S.; Fradet-Turcotte, A.; Stewart, G. S.; Raught, B.; Hakem, A. et al.; Hakem, R.: RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks. Proc Natl Acad Sci U S A 110 (52), pp. 20982 - 7 (2013)

Panier, S.; Durocher, D.: Push back to respond better: regulatory inhibition of the DNA double-strand break response. Nat Rev Mol Cell Biol 14 (10), pp. 661 - 72 (2013)

Panier, S.; Ichijima, Y.; Fradet-Turcotte, A.; Leung, C. C.; Kaustov, L.; Arrowsmith, C. H.; Durocher, D.: Tandem protein interaction modules organize the ubiquitin-dependent response to DNA double-strand breaks. Mol Cell 47 (3), pp. 383 - 95 (2012)

Bohgaki, T.; Bohgaki, M.; Cardoso, R.; Panier, S.; Zeegers, D.; Li, L.; Stewart, G. S.; Sanchez, O.; Hande, M. P.; Durocher, D. et al.; Hakem, A.; Hakem, R.: Genomic instability, defective spermatogenesis, immunodeficiency, and cancer in a mouse model of the RIDDLE syndrome. PLoS Genet 7 (4), p. e1001381 (2011)

Al-Hakim, A.; Escribano-Diaz, C.; Landry, M. C.; O'Donnell, L.; Panier, S.; Szilard, R. K.; Durocher, D.: The ubiquitous role of ubiquitin in the DNA damage response. DNA Repair (Amst) 9 (12), pp. 1229 - 40 (2010)

O'Donnell, L.; Panier, S.; Wildenhain, J.; Tkach, J. M.; Al-Hakim, A.; Landry, M. C.; Escribano-Diaz, C.; Szilard, R. K.; Young, J. T.; Munro, M. et al.; Canny, M. D.; Kolas, N. K.; Zhang, W.; Harding, S. M.; Ylanko, J.; Mendez, M.; Mullin, M.; Sun, T.; Habermann, B.; Datti, A.; Bristow, R. G.; Gingras, A. C.; Tyers, M. D.; Brown, G. W.; Durocher, D.: The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombination. Mol Cell 40 (4), pp. 619 - 31 (2010)

Nakada, S.; Tai, I.; Panier, S.; Al-Hakim, A.; Iemura, S.; Juang, Y. C.; O'Donnell, L.; Kumakubo, A.; Munro, M.; Sicheri, F. et al.; Gingras, A. C.; Natsume, T.; Suda, T.; Durocher, D.: Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1. Nature 466 (7309), pp. 941 - 6 (2010)

Ramachandran, S.; Chahwan, R.; Nepal, R. M.; Frieder, D.; Panier, S.; Roa, S.; Zaheen, A.; Durocher, D.; Scharff, M. D.; Martin, A.: The RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombination. Proc Natl Acad Sci U S A 107 (2), pp. 809 - 14 (2010)

Lilley, C. E.; Chaurushiya, M. S.; Boutell, C.; Landry, S.; Suh, J.; Panier, S.; Everett, R. D.; Stewart, G. S.; Durocher, D.; Weitzman, M. D.: A viral E3 ligase targets RNF8 and RNF168 to control histone ubiquitination and DNA damage responses. EMBO J 29 (5), pp. 943 - 55 (2010)

Panier, S.; Durocher, D.: Regulatory ubiquitylation in response to DNA double-strand breaks. DNA Repair (Amst) 8 (4), pp. 436 - 43 (2009)

Doil, C.; Mailand, N.; Bekker-Jensen, S.; Menard, P.; Larsen, D. H.; Pepperkok, R.; Ellenberg, J.; Panier, S.; Durocher, D.; Bartek, J. et al.; Lukas, J.; Lukas, C.: RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins. Cell 136 (3), pp. 435 - 46 (2009)

Stewart, G. S.; Panier, S.; Townsend, K.; Al-Hakim, A. K.; Kolas, N. K.; Miller, E. S.; Nakada, S.; Ylanko, J.; Olivarius, S.; Mendez, M. et al.; Oldreive, C.; Wildenhain, J.; Tagliaferro, A.; Pelletier, L.; Taubenheim, N.; Durandy, A.; Byrd, P. J.; Stankovic, T.; Taylor, A. M.; Durocher, D.: The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage. Cell 136 (3), pp. 420 - 34 (2009)