Dr. Stephanie Panier (she/her)

Max Planck Research Group Leader


Scientific Career

2020 - today    |    Max Planck Research Group Leader
Max Planck Institute for Biology of Ageing, Cologne, Germany
2020 - heute    |    Principal Investigator
Institute for Genome Stability in Aging and Disease, Medical Faculty, University of Cologne
2013 - 2019    |    Postdoctoral Research Fellow
with Prof. Dr. Simon Boulton at the Francis Crick Institut, London, UK
2008 - 2013    |    PhD student
with Prof. Dr. Daniel Durocher at the Lunenfeld-Tanenbaum Research Institute and at the Department of Molecular Genetics, University of Toronto, Canada
2001 - 2006    |    Student of Biology
at the Department for Biology, Ruprecht-Karls-Universität Heidelberg, Germany


2008 - 2013    |    Graduate studies
Department of Molecular Genetics, University of Toronto, Canada
2001 - 2006    |    Undergraduate studies
Ruprecht-Karls-Universität Heidelberg, Germany


2013    |    Vivash Award for the best PhD thesis
at the Department of Molecular Genetics University of Toronto, Canada

Third-party funding

2023 - 2026    |   DFG Research Unit FOR5504
2023                |   FEBS Excellence Award
2013 - 2014    |   EMBO Long-Term Fellowship
2010 - 2013    |   Vanier Canada Graduate Scholarship
2008 - 2010    |   PhD Fellowship of the Boehringer Ingelheim Fonds
2023                |   EIRR21st Fellowship - Excellence in Radiation Research for the 21st Century of the Canadian Institutes of Health Research

Scientific Activities / Memberships

Since 2021    |    Member - German-Israeli research network "Minerva Center for Biological Mechanisms of Healthy Aging"
Since 2020    |    German Association of Ageing Research (minute keeper since 2021)
Since 2020    |    German Society for Research on DNA Repair (advisory board since 2022)
Since 2020    |    Principal Investigator - Cologne Excellence Cluster “Cellular Stress Responses in Aging-Associated Diseases” (CECAD), University of Cologne, Germany

Service to Scientific Community
2023 - 2026    |   Vice coordinator
Research Group FOR5504 of the German Research Council, Physiological causes and consequences of genome instability, University of Cologne and Max Planck Insitute for Biology of Ageing, Cologne, Germany
Since 2022       |   MPI-Age institute representative
Biology and Medicine Section (BMS) of the Max Planck Society’s scientific council
2021 - 2022    |   Deputy Gender Equality Officer
Max Planck Institute for Biology of Ageing, Cologne, Germany

Selected Publications

SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance
Panier, S., Maric, M., Hewitt, G., Mason-Osann, E., Gali, H., Dai, A., Labadorf, A., Guervilly, J. H., Ruis, P., Segura-Bayona, S., Belan, O., Marzec, P., Gaillard, P. H. L., Flynn, R. L., Boulton, S. J.
(2019) Mol Cell, 76, 1, 27-43 e11

Double-strand break repair: 53BP1 comes into focus
Panier, S., Boulton, S. J.
(2014) Nat Rev Mol Cell Biol, 15, 1, 7-18

Tandem protein interaction modules organize the ubiquitin-dependent response to DNA double-strand breaks
Panier, S., Ichijima, Y., Fradet-Turcotte, A., Leung, C. C., Kaustov, L., Arrowsmith, C. H., Durocher, D.
(2012) Mol Cell, 47, 3, 383-95

The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombination
O'Donnell, L., Panier, S., Wildenhain, J., Tkach, J. M., Al-Hakim, A., Landry, M. C., Escribano-Diaz, C., Szilard, R. K., Young, J. T., Munro, M., Canny, M. D., Kolas, N. K., Zhang, W., Harding, S. M., Ylanko, J., Mendez, M., Mullin, M., Sun, T., Habermann, B., Datti, A., Bristow, R. G., Gingras, A. C., Tyers, M. D., Brown, G. W., Durocher, D.
(2010) Mol Cell, 40, 4, 619-31

The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage
Stewart, G. S., Panier, S., Townsend, K., Al-Hakim, A. K., Kolas, N. K., Miller, E. S., Nakada, S., Ylanko, J., Olivarius, S., Mendez, M., Oldreive, C., Wildenhain, J., Tagliaferro, A., Pelletier, L., Taubenheim, N., Durandy, A., Byrd, P. J., Stankovic, T., Taylor, A. M., Durocher, D.
(2009) Cell, 136, 3, 420-34

Full publication list; see https://www.age.mpg.de/panier/publications

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