Publications of J. H. K. Kauppila

Nicholls, T. J.; Spahr, H.; Jiang, S.; Siira, S. J.; Koolmeister, C.; Sharma, S.; Kauppila, J. H. K.; Jiang, M.; Kaever, V.; Rackham, O. et al.; Chabes, A.; Falkenberg, M.; Filipovska, A.; Larsson, N.G.; Gustafsson, C. M.: Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria. Mol Cell 76 (5), pp. 784 - 796 e6 (2019)

Ramos, E.S.; Motori, E.; Bruser, C.; Kuhl, I.; Yeroslaviz, A.; Ruzzenente, B.; Kauppila, J. H. K.; Busch, J.; Hultenby, K.; Habermann, B. H. et al.; Jakobs, S.; Larsson, N.G.; Mourier, A.: Mitochondrial fusion is required for regulation of mitochondrial DNA replication. PLoS Genet 15 (6), p. e1008085 (2019)

Bacman, S. R.; Kauppila, J. H. K.; Pereira, C. V.; Nissanka, N.; Miranda, M.; Pinto, M.; Williams, S. L.; Larsson, N.G.; Stewart, J.; Moraes, C. T.: Author Correction: MitoTALEN reduces mutant mtDNA load and restores tRNA(Ala) levels in a mouse model of heteroplasmic mtDNA mutation. Nat Med 24 (12), p. 1940 (2018)

Bacman, S. R.; Kauppila, J. H. K.; Pereira, C. V.; Nissanka, N.; Miranda, M.; Pinto, M.; Williams , S. L.; Larsson, N.G.; Stewart, J.; Moraes, C. T.: MitoTALEN reduces mutant mtDNA load and restores tRNA(Ala) levels in a mouse model of heteroplasmic mtDNA mutation. Nat Med 24 (11), pp. 1696 - 1700 (2018)

Kauppila, J. H. K.; Bonekamp, N.; Mourier, A.; Isokallio, M.; Just, A.; Kauppila, T.; Stewart, J.; Larsson, N.G.: Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice. Nucleic Acids Res 46 (13), pp. 6642 - 6669 (2018)

Kauppila, J. H. K.; Baines, H. L.; Bratic, A.; Simard, M.-L.; Freyer, C.; Mourier, A.; Stamp, C.; Filograna, R.; Larsson, N.G.; Greaves, L. C. et al.; Stewart, J. B.: A Phenotype-Driven Approach to Generate Mouse Models with Pathogenic mtDNA Mutations Causing Mitochondrial Disease. Cell Rep 16 (11), pp. 2980 - 90 (2016)

Kauppila, J. H. K.; Baines, H. L.; Bratic, A.; Simard, M.-L.; Freyer, C.; Mourier, A.; Stamp, C.; Filograna, R.; Larsson, N.G.; Greaves, L. C. et al.; Stewart, J. B.: A Phenotype-Driven Approach to Generate Mouse Models with Pathogenic mtDNA Mutations Causing Mitochondrial Disease. Cell reports 16 (11), pp. 2980 - 2990 (2016)

Kauppila, J. H. K.; Stewart, J. B.: Mitochondrial DNA: Radically free of free-radical driven mutations. Biochim Biophys Acta 1847 (11), pp. 1354 - 61 (2015)