Publications of J. Nuechel

Fernandes, S. A.; Angelidaki, D.-D.; Nuechel, J.; Pan, J.; Gollwitzer, P.; Elkis, Y.; Artoni, F.; Wilhelm, S.; Kovacevic-Sarmiento, M.; Demetriades, C.: Spatial and functional separation of mTORC1 signalling in response to different amino acid sources. Nature Cell Biology (2024)

Nicastro , R.; Brohée, L.; Alba, J.; Nuechel, J.; Figlia, G.; Kipschull, S.; Gollwitzer, P.; Romero-Pozuelo, J.; Fernandes, S. A.; Lamprakis, A. et al.; Vanni, S.; Teleman, A. A.; De Virgilio, C.; Demetriades, C.: Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitor. Nature Cell Biology (2023)

Nicastro , R.; Brohée, L.; Alba, J.; Nuechel, J.; Figlia, G.; Kipschull , S.; Gollwitzer, P.; Romero-Pozuelo, J.; Fernandes, S. A.; Lamprakis, A. et al.; Vanni, S.; Teleman, A. A.; De Virgilio, C.; Demetriades, C.: Malonyl-CoA is an ancient physiological ATP-competitive mTORC1 inhibitor. bioRxiv, p. 2022.11.06.515351 (2022)

Demetriades, C.; Nuechel, J.; Plomann, M.: GRASPing the unconventional secretory machinery to bridge cellular stress signaling to the extracellular proteome. Cell Stress 5 (11), pp. 173 - 175 (2021)

Nuechel, J.; Tauber, M.; Nolte, J. L.; Morgelin, M.; Turk, C.; Eckes, B.; Demetriades, C.; Plomann, M.: An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress. Mol Cell 81 (16), pp. 3275 - 3293 (2021)

Nuechel, J.; Ghatak, S.; Zuk, A. V.; Illerhaus, A.; Morgelin, M.; Schonborn, K.; Blumbach, K.; Wickström, S. A.; Krieg, T.; Sengle, G. et al.; Plomann, M.; Eckes, B.: TGFB1 is secreted through an unconventional pathway dependent on the autophagic machinery and cytoskeletal regulators. Autophagy 14 (3), pp. 465 - 486 (2018)