Publications of M. Graef

Gross, A.; Ghillebert, R.; Schuetter, M.; Reinartz, E.; Rowland, A.; Bishop, B. C.; Stumpe, M.; Dengjel, J.; Graef, M.: A metabolite sensor subunit of the Atg1/ULK complex regulates selective autophagy. Nature Cell Biology (2024)

Dabrowski, R.; Tulli, S.; Graef, M.: Parallel phospholipid transfer by Vps13 and Atg2 determines autophagosome biogenesis dynamics. Journal of Cell Biology 222 (2023)

Grossbach, J.; Gillet, L.; Clement-Ziza, M.; Schmalohr, C. L.; Schubert, O. T.; Schütter, M.; Mawer, J. S. P.; Barnes, C. A.; Bludau, I.; Weith, M. et al.; Tessarz, P.; Graef, M.; Aebersold, R.; Beyer, A.: The impact of genomic variation on protein phosphorylation states and regulatory networks. Mol Syst Biol 18 (5), p. e10712 (2022)

Kochan, D. Z.; Mawer, J. S. P.; Massen, J.; Tishinov, K.; Parekh, S.; Graef, M.; Spang, A.; Tessarz, P.: The RNA-binding protein Puf5 contributes to buffering of mRNA upon chromatin-mediated changes in nascent transcription. J Cell Sci 15 (134), p. jcs259051 (2021)

Sawa-Makarska, J.; Baumann, V.; Coudevylle, N.; von Bulow, S.; Nogellova, V.; Abert, C.; Schuschnig, M.; Graef, M.; Hummer, G.; Martens, S.: Reconstitution of autophagosome nucleation defines Atg9 vesicles as seeds for membrane formation. Science 369 (6508), p. eaaz7714 (2020)

Gross, A.; Graef, M.: Stress eating: Autophagy targets nuclear pore complexes. J Cell Biol 219 (7) (2020)

Graef, M.: Recent advances in the understanding of autophagosome biogenesis. F1000Res 9 (2020)

Schütter, M.; Graef, M.: Localized de novo phospholipid synthesis drives autophagosome biogenesis. Autophagy 16 (4), pp. 770 - 771 (2020)

Schütter, M.; Giavalisco, P.; Brodesser, S.; Graef, M.: Local Fatty Acid Channeling into Phospholipid Synthesis Drives Phagophore Expansion during Autophagy. Cell (180), pp. 135 - 149 (2019)

Gross, A.; Graef, M.: Mechanisms of Autophagy in Metabolic Stress Response. J Mol Biol S0022-2836(19), pp. 30559 - 5 (2019)

Cui, R.; Medeiros, T. C.; Willemsen, D.; Iasi, L.N.M.; Collier, G. E.; Graef, M.; Reichard, M.; Valenzano, D. R.: Relaxed Selection Limits Lifespan by Increasing Mutation Load. Cell 178 (2), pp. 385 - 399 e20 (2019)

Medeiros, T. C.; Graef, M.: Autophagy determines mtDNA copy number dynamics during starvation. Autophagy 15 (1), pp. 178 - 179 (2019)

Graef, M.: Lipid droplet-mediated lipid and protein homeostasis in budding yeast. FEBS Lett (592(8)), pp. 1291 - 1303 (2018)

Graef, M.: A dividing matter: Drp1/Dnm1-independent mitophagy. J Cell Biol 215 (5), pp. 599 - 601 (2016)

Klionsky, D. J.; Graef, M.: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12 (1), pp. 1 - 222 (2016)

Velazquez, A.; Graef, M.: Autophagy regulation depends on ER homeostasis controlled by lipid droplets. Autophagy 12 (8), pp. 1409 - 10 (2016)

Velazquez, A.; Tatsuta, T.; Ghillebert, R.; Drescher, I.; Graef, M.: Lipid droplet-mediated ER homeostasis regulates autophagy and cell survival during starvation. J Cell Biol 212 (6), pp. 621 - 31 (2016)

Vlahakis, A.; Graef, M.; Nunnari, J.; Powers, T.: TOR complex 2-Ypk1 signaling is an essential positive regulator of the general amino acid control response and autophagy. Proc Natl Acad Sci U S A 111 (29), pp. 10586 - 91 (2014)

Graef, M.; Seewald, G.; Langer, T.: Substrate recognition by AAA+ ATPases: distinct substrate binding modes in ATP-dependent protease Yme1 of the mitochondrial intermembrane space. Mol Cell Biol 27 (7), pp. 2476 - 85 (2007)

Graef, M.; Langer, T.: Substrate specific consequences of central pore mutations in the i-AAA protease Yme1 on substrate engagement. J Struct Biol 156 (1), pp. 101 - 8 (2006)