Publications

Timofeev, O.; Giron, P.; Lawo, S.; Pichler, M.; Noeparast, M.: ERK pathway agonism for cancer therapy: evidence, insights, and a target discovery framework. npj Precision Oncology 8, 70 (2024)

Zhang, P.; Catterson, J. H.; Grönke, S.; Partridge, L.: Inhibition of S6K lowers age-related inflammation and increases lifespan through the endolysosomal system. Nature Aging (2024)

De Solis, A. J.; Del Río-Martín, A.; Radermacher, J.; Chen, W.; Steuernagel, L.; Bauder, C. A.; Eggersmann, F. R.; Morgan, D. A.; Cremer, A.-L.; Sué, M. et al.; Germer, M.; Kukat, C.; Vollmar, S.; Backes, H.; Rahmouni, K.; Kloppenburg, P.; Brüning, J. C.: Reciprocal activity of AgRP and POMC neurons governs coordinated control of feeding and metabolism. Nature Metabolism (2024)

Almannai, M.; Marafi, D.; Zaki, M. S.; Maroofian, R.; Efthymiou, S.; Saadi, N. W.; Filimban, B.; Dafsari, H. S.; Rahman, F.; Maqbool, S. et al.; Faqeih, E.; Al Mutairi, F.; Alsharhan, H.; Abdelaty, O.; Bin‐Hasan, S.; Duan, R.; Noureldeen, M. M.; Alqattan, A.; Houlden, H.; Hunter, J. V.; Posey, J. E.; Lupski, J. R.; El‐Hattab, A. W.: Expanding the phenotype ofPPP1R21‐related neurodevelopmental disorder. Clinical Genetics (2024)

Baum, E.; Huang, W.; Vincent-Delorme, C.; Brunelle, P.; Antebi, A.; Dafsari, H. S.: Novel Genetic and Phenotypic Expansion in Ameliorated PUF60-Related Disorders. International Journal of Molecular Sciences 25, p. 2053 (2024)

Gross, A.; Ghillebert, R.; Schuetter, M.; Reinartz, E.; Rowland, A.; Bishop, B. C.; Stumpe, M.; Dengjel, J.; Graef, M.: A metabolite sensor subunit of the Atg1/ULK complex regulates selective autophagy. Nature Cell Biology (2024)

Wang, X.; Jiang, Q.; Zhang, H.; He, Z.; Song, Y.; Chen, Y.; Tang, N.; Zhou, Y.; Li, Y.; Antebi, A. et al.; Wu, L.; Han, J.-D. J.; Shen, Y.: Tissue-specific profiling of age-dependent miRNAomic changes in Caenorhabditis elegans. Nature Communications 15, 955 (2024)

Calabrese, C.; Nolte, H.; Pitman, M. R.; Ganesan, R.; Lampe, P.; Laboy, R.; Ripa, R.; Fischer, J.; Polara, R.; Panda, S. K. et al.; Chipurupalli, S.; Gutierrez, S.; Thomas, D.; Pitson, S. M.; Antebi, A.; Robinson, N.: Mitochondrial translocation of TFEB regulates complex I and inflammation. EMBO Reports (2024)

Titze, V. M.; Caixeiro, S.; Dinh, V. S.; König, M.; Rübsam, M.; Pathak, N.; Schumacher, A. L.; Germer, M.; Kukat, C.; Niessen, C. M. et al.; Schubert, M.; Gather, M. C.: Hyperspectral confocal imaging for high-throughput readout and analysis of bio-integrated microlasers. Nature Protocols (2024)

Vossen, C.; Schmidt, P.; Wunderlich, C. M.; Mittenbühler, M. J.; Tapken, C.; Wienand, P.; Mirabella, P. N.; Cabot, L.; Schumacher, A. L.; Folz-Donahue, K. et al.; Kukat, C.; Voigt, I.; Brüning, J. C.; Fenselau, H.; Wunderlich, F. T.: An Approach to Intersectionally Target Mature Enteroendocrine Cells in the Small Intestine of Mice. Cells 13, p. 102 (2024)

Ahola, S.; Langer, T.: Ferroptosis in mitochondrial cardiomyopathy. Trends in Cell Biology 34, pp. 150 - 160 (2024)

Baghdadi, M.; Nespital, T.; Monzó, C.; Deelen, J.; Grönke, S.; Partridge, L.: Intermittent rapamycin feeding recapitulates some effects of continuous treatment while maintaining lifespan extension. Molecular Metabolism 81, 101902, p. 101902 (2024)

Baker, M. J.; Blau, K. U.; Anderson, A. J.; Palmer, C. S.; Fielden, L. F.; Crameri, J. J.; Milenkovic, D.; Thorburn, D. R.; Frazier, A. E.; Langer, T. et al.; Stojanovski, D.: CLPB disaggregase dysfunction impacts the functional integrity of the proteolytic SPY complex. Journal of Cell Biology 223 (2024)

Burger, N.; Mittenbühler, M. J.; Xiao, H.; Shin, S.; Bozi, L. H.M.; Wei, S.; Sprenger, H.-G.; Sun, Y.; Zhu, Y.; Darabedian, N. et al.; Petrocelli, J. J.; Muro, P. L.-; Che, J.; Chouchani, E. T.: A comprehensive landscape of the zinc-regulated human proteome. bioRxiv, p. 2024.01.04.574225 (2024)

Flümann, R.; Hansen, J.; Meinel, J.; Pfeiffer, P.; Goldfarb Wittkopf, H.; Lütz, A.; Wirtz, J.; Möllmann, M.; Zhou, T.; Tabatabai, A. et al.; Lohmann, T.; Jauch, M.; Beleggia, F.; Pelzer, B.; Ullrich, F.; Höfmann, S.; Arora, A.; Persigehl, T.; Büttner, R.; von Tresckow, B.; Klein, S.; Jachimowicz, R. D.; Reinhardt, H. C.; Knittel, G.: An inducibleCd79bmutation confers ibrutinib sensitivity in mouse models ofMyd88-driven diffuse large B-cell lymphoma. Blood Advances 8, pp. 1063 - 1074 (2024)

Hu, Q.; Xu, Y.; Song, M.; Dai, Y.; Antebi, A.; Shen, Y.: BLMP-1 is a critical temporal regulator of dietary-restriction-induced response in Caenorhabditis elegans. Cell Reports 43, 113959, p. 113959 (2024)

Huppertz, I.: Free ribosomal proteins as culprits for nucleolar stress. Molecular Cell 84, pp. 1400 - 1402 (2024)

Khetarpal, S. A.; Li, H.; Vitale, T.; Rhee, J.; Grauvogel, L.; Castro, C.; Mittenbühler, M. J.; Houstis, N. E.; Vargas-Castillo, A.; Smythers, A. L. et al.; Liu, J.; Curtin, C.; Sprenger, H.-G.; Blackmore, K. A.; Kuznetsov, A.; Freeman, R.; Bogoslavski, D.; Ellinor, P. T.; Asnani, A.; Dumesic, P. A.; Puigserver, P.; Roh, J. D.; Spiegelman, B. M.; Rosenzweig, A.: Cardiomyocyte PGC-1α enables physiological adaptations to endurance exercise through suppression of GDF15 and cardiac atrophy. bioRxiv, p. 2024.01.30.578093 (2024)

Panier, S.; Wang, S.; Schumacher, B.: Genome Instability and DNA Repair in Somatic and Reproductive Aging. Annual Review of Pathology: Mechanisms of Disease 19 (2024)

Šetinc, M.; Celinšćak, Ž.; Bočkor, L.; Petranović, M. Z.; Marković, A. S.; Salihović, M. P.; Deelen, J.; Škarić-Jurić, T.: The role of longevity-related genetic variant interactions as predictors of survival after 85 years of age. Mechanisms of Ageing and Development, 111926, p. 111926 (2024)